Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0946 | 0.2658 | 0.2658 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0138 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0082 | 0.0082 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0946 | 0.2658 | 1 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0946 | 0.2658 | 0.5 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0138 | 0.0032 | 0.0032 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0946 | 0.2658 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.3204 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0946 | 0.2658 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.3204 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0946 | 0.2658 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0138 | 0.0032 | 0.0032 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0291 | 0.0531 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0138 | 0.0032 | 0.0032 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.3204 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0291 | 0.0531 | 0.1998 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0138 | 0.0032 | 0.0032 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0138 | 0.0032 | 0.0032 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0291 | 0.0531 | 0.1998 |
Onchocerca volvulus | 0.0163 | 0.0114 | 0.043 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0138 | 0.0032 | 0.0032 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.3204 | 1 | 1 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0141 | 0.0042 | 0.0042 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0291 | 0.0531 | 1 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0138 | 0.0032 | 0.0032 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0946 | 0.2658 | 1 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0292 | 0.0531 | 0.0531 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0138 | 0.0032 | 0.0032 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0138 | 0.0032 | 0.0032 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0138 | 0.0032 | 0.0032 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0138 | 0.0032 | 0.0032 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0946 | 0.2658 | 0.2658 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0654 | 0.171 | 0.5 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0138 | 0.0032 | 0.0032 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0946 | 0.2658 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0082 | 0.0082 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0138 | 0.0032 | 0.0032 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0291 | 0.0531 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0138 | 0.0032 | 0.0032 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0138 | 0.0032 | 0.0032 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0141 | 0.0042 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.0042 | 0.0042 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0946 | 0.2658 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.0499 | 0.0499 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0946 | 0.2658 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0138 | 0.0032 | 0.0032 |
Onchocerca volvulus | 0.0946 | 0.2658 | 1 | |
Onchocerca volvulus | 0.0141 | 0.0042 | 0.0159 | |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0946 | 0.2658 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0291 | 0.0531 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.