Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0623 | 0.4528 | 0.5588 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0644 | 0.481 | 0.481 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0663 | 0.5066 | 0.457 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0497 | 0.2815 | 0.2244 |
Brugia malayi | Protein kinase c protein 2 | 0.0824 | 0.7261 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1026 | 1 | 1 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0497 | 0.2815 | 0.5 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0497 | 0.2815 | 0.5 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0497 | 0.2815 | 0.2815 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0497 | 0.2815 | 0.5 |
Giardia lamblia | Kinase, CMGC GSK | 0.0497 | 0.2815 | 0.5 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0497 | 0.2815 | 0.2093 |
Brugia malayi | protein kinase C II. | 0.0663 | 0.5066 | 0.5062 |
Trypanosoma brucei | protein kinase, putative | 0.0497 | 0.2815 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.079 | 0.6789 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0357 | 0.0913 | 0.0913 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0663 | 0.5066 | 0.5066 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0491 | 0.2739 | 0.2009 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0644 | 0.481 | 0.4288 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0497 | 0.2815 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0558 | 0.3644 | 0.3863 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0663 | 0.5066 | 0.6637 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0663 | 0.5066 | 0.457 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.1026 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0497 | 0.2815 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1026 | 1 | 1 |
Echinococcus multilocularis | protein kinase shaggy | 0.0497 | 0.2815 | 0.2093 |
Giardia lamblia | Kinase, CMGC GSK | 0.0497 | 0.2815 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0497 | 0.2815 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.088 | 0.8021 | 0.8021 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0497 | 0.2815 | 0.2244 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0679 | 0.5282 | 0.7059 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0497 | 0.2815 | 0.5 |
Onchocerca volvulus | 0.0497 | 0.2815 | 1 | |
Echinococcus multilocularis | serine threonine protein kinase | 0.088 | 0.8021 | 0.7822 |
Loa Loa (eye worm) | hypothetical protein | 0.0644 | 0.481 | 0.6137 |
Echinococcus granulosus | protein kinase shaggy | 0.0497 | 0.2815 | 0.2815 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0497 | 0.2815 | 1 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0497 | 0.2815 | 0.5 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0644 | 0.481 | 0.4288 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0497 | 0.2815 | 1 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0497 | 0.2815 | 0.2093 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.