Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0334 | 0.3623 | 1 |
Echinococcus granulosus | glycogen debranching enzyme | 0.0126 | 0.0523 | 0.0381 |
Schistosoma mansoni | alpha-glucosidase | 0.0404 | 0.4672 | 0.4672 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0761 | 1 | 0.5 |
Toxoplasma gondii | Amylo-alpha-1,6-glucosidase | 0.0126 | 0.0523 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0101 | 0.0148 | 0.0148 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.1061 | 0.1061 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0761 | 1 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0454 | 0.5414 | 0.5345 |
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.0126 | 0.0523 | 1 |
Onchocerca volvulus | 0.0359 | 0.4003 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0523 | 0.0381 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0761 | 1 | 1 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0761 | 1 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0334 | 0.3623 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0454 | 0.5414 | 0.5345 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0101 | 0.0148 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0101 | 0.0148 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0454 | 0.5414 | 0.5345 |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.0126 | 0.0523 | 0.0381 |
Schistosoma mansoni | alpha-glucosidase | 0.0404 | 0.4672 | 0.4672 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0101 | 0.0148 | 0.5 |
Echinococcus multilocularis | glycogen debranching enzyme | 0.0126 | 0.0523 | 0.0381 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0454 | 0.5414 | 0.5345 |
Giardia lamblia | 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase | 0.0126 | 0.0523 | 0.5 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0126 | 0.0523 | 0.108 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0454 | 0.5414 | 0.5345 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0126 | 0.0523 | 0.108 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0101 | 0.0148 | 0.5 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0761 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.