Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | RAR-like nuclear receptor | 0.0054 | 0.2998 | 0.291 |
Schistosoma mansoni | lamin | 0.0031 | 0.1174 | 0.1062 |
Leishmania major | trypanothione reductase | 0.0044 | 0.2191 | 0.5 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0699 | 0.2106 |
Echinococcus granulosus | lamin | 0.0031 | 0.1174 | 0.3651 |
Brugia malayi | nuclear receptor NHR-67 | 0.0025 | 0.0699 | 0.2106 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0025 | 0.0699 | 0.1999 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0045 | 0.2239 | 0.7359 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0054 | 0.2998 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0054 | 0.2998 | 0.291 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.2998 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0025 | 0.0699 | 0.1999 |
Brugia malayi | tailless protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | nuclear hormone receptor | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0044 | 0.2191 | 0.6604 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0025 | 0.0699 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0054 | 0.2998 | 0.9034 |
Onchocerca volvulus | 0.0031 | 0.1174 | 0.2065 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Brugia malayi | ecdysone receptor | 0.0025 | 0.0699 | 0.2106 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0054 | 0.2998 | 0.291 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0054 | 0.2998 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0699 | 0.1999 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.184 | 0.5545 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0111 | 0.7636 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | nuclear receptor RXR | 0.0028 | 0.0945 | 0.2848 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0054 | 0.2998 | 0.9034 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0044 | 0.2191 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | glutathione reductase | 0.0044 | 0.2191 | 0.6604 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0945 | 0.2848 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.3318 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0044 | 0.2191 | 0.6604 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0025 | 0.0699 | 0.2106 |
Echinococcus granulosus | FTZ F1 alpha | 0.0054 | 0.2998 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0028 | 0.0945 | 0.2856 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1174 | 0.3537 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0025 | 0.0699 | 0.1999 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0054 | 0.2998 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.3318 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0054 | 0.2998 | 0.9034 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0054 | 0.2998 | 1 |
Echinococcus multilocularis | lamin | 0.0031 | 0.1174 | 0.3651 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0124 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0699 | 0.2106 |
Schistosoma mansoni | thyroid hormone receptor | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0025 | 0.0699 | 0.2106 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.01 | 0.6733 | 0.8342 |
Echinococcus multilocularis | musashi | 0.0031 | 0.1174 | 0.3651 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.1174 | 0.3537 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.0699 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Loa Loa (eye worm) | DR-78 | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1127 | 0.3397 |
Brugia malayi | ecdysteroid receptor | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0699 | 0.0582 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.2998 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.3318 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0111 | 0.7636 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.01 | 0.6733 | 0.8342 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.0699 | 0.1999 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0699 | 0.1999 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0054 | 0.2998 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0054 | 0.2998 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.01 | 0.6733 | 0.8342 |
Mycobacterium tuberculosis | Probable reductase | 0.01 | 0.6733 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0124 | 0.0375 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | steroid hormone receptor | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0025 | 0.0699 | 0.0582 |
Plasmodium vivax | glutathione reductase, putative | 0.0044 | 0.2191 | 0.5 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Schistosoma mansoni | thyroid hormone receptor | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0699 | 0.0582 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0025 | 0.0699 | 0.0582 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0044 | 0.2191 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.1174 | 0.3651 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0054 | 0.2998 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Onchocerca volvulus | 0.0054 | 0.2998 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0054 | 0.2998 | 0.9034 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0054 | 0.2998 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.2998 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0025 | 0.0699 | 0.1999 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.01 | 0.6733 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.01 | 0.6733 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0945 | 0.2848 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.2998 | 0.291 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.1174 | 0.3651 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0124 | 0.0375 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0054 | 0.2998 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.1174 | 0.1062 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0111 | 0.7636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | glutathione reductase | 0.0044 | 0.2191 | 0.6604 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0028 | 0.0945 | 0.2848 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0699 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.184 | 0.5545 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0054 | 0.2998 | 0.9034 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0054 | 0.2998 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0054 | 0.2998 | 0.9034 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0025 | 0.0699 | 0.1999 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0945 | 0.2848 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0054 | 0.2998 | 1 |
Schistosoma mansoni | lamin | 0.0031 | 0.1174 | 0.1062 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.1174 | 0.3651 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0699 | 0.1999 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0025 | 0.0699 | 0.0582 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0028 | 0.0945 | 0.2856 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.2998 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0054 | 0.2998 | 0.9034 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0054 | 0.2998 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0044 | 0.2191 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0124 | 0.0375 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0054 | 0.2998 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0044 | 0.2191 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0054 | 0.2998 | 0.291 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0699 | 0.0582 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0054 | 0.2998 | 0.9034 |
Brugia malayi | conserved hypotetical protein | 0.0025 | 0.0699 | 0.2106 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0045 | 0.2239 | 0.7359 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0054 | 0.2998 | 0.291 |
Brugia malayi | nuclear receptor RXR | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.3318 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Onchocerca volvulus | 0.0031 | 0.1174 | 0.2065 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0025 | 0.0699 | 0.2106 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0054 | 0.2998 | 0.9034 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.184 | 0.1737 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0699 | 0.1999 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0028 | 0.0945 | 0.0831 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.1174 | 0.3537 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.1174 | 0.3537 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0945 | 0.0831 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0054 | 0.2998 | 0.9034 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0054 | 0.2998 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.1174 | 0.3537 |
Toxoplasma gondii | thioredoxin reductase | 0.0044 | 0.2191 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.0699 | 0.2106 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0054 | 0.2998 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0111 | 0.7636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.2998 | 0.9034 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0054 | 0.2998 | 0.291 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0699 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0025 | 0.0699 | 0.2106 |
Schistosoma mansoni | coup transcription factor | 0.0054 | 0.2998 | 0.291 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0699 | 0.2106 |
Trypanosoma brucei | trypanothione reductase | 0.0044 | 0.2191 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0054 | 0.2998 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.