Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.0052 | 0.0099 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0013 | 0.0005 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0472 | 0.0516 | 0.3911 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0091 | 0.0043 | 0.0076 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.1064 | 0.1253 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 0.0894 | 0.0891 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0091 | 0.0043 | 0.0076 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.0139 | 0.0101 | 0.0485 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0139 | 0.0101 | 0.0094 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0178 | 0.0151 | 0.0143 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0356 | 0.0372 | 0.1687 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.0139 | 0.0101 | 0.0224 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0087 | 0.0037 | 0.0029 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0087 | 0.0037 | 0.0061 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | ACC-1 protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.0808 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.1064 | 0.1253 | 1 |
Onchocerca volvulus | 0.0091 | 0.0043 | 0.0405 | |
Loa Loa (eye worm) | LGC-31 protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0178 | 0.0151 | 0.0143 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.0222 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Brugia malayi | Sodium/calcium exchanger protein | 0.3235 | 0.3957 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0178 | 0.0151 | 0.0147 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0356 | 0.0372 | 0.1687 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0048 | 0.0044 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0204 | 0.0183 | 0.0176 |
Schistosoma mansoni | sodium/calcium exchanger | 0.8087 | 1 | 1 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0731 | 0.0839 | 0.4597 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0087 | 0.0037 | 0.0029 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0007 | 0.0054 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0356 | 0.0372 | 0.0365 |
Echinococcus granulosus | nAChR subunit | 0.0091 | 0.0043 | 0.0035 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.0139 | 0.0101 | 0.0094 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0087 | 0.0037 | 0.0029 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0178 | 0.0151 | 0.0349 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0091 | 0.0043 | 0.0076 |
Onchocerca volvulus | Sodium\/potassium\/calcium exchanger | 0.0204 | 0.0183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 0.2719 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0087 | 0.0037 | 0.0033 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0356 | 0.0372 | 0.2967 |
Loa Loa (eye worm) | solute carrier family 8 | 0.8087 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0139 | 0.0101 | 0.0094 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.0222 | 0.0215 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.1064 | 0.1253 | 0.1247 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.2589 |
Echinococcus multilocularis | sodium calcium exchanger | 0.8087 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0096 | 0.0048 | 0.004 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.0633 | 0.063 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0087 | 0.0037 | 0.0061 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger 6 | 0.0204 | 0.0183 | 0.0176 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0847 | 0.0983 | 0.7765 |
Loa Loa (eye worm) | hypothetical protein | 0.0689 | 0.0787 | 0.0784 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0092 | 0.0044 | 0.0036 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.1064 | 0.1253 | 0.7184 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0356 | 0.0372 | 0.2719 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Schistosoma mansoni | na/ca exchanger | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0087 | 0.0037 | 0.0033 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0087 | 0.0037 | 0.0061 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0087 | 0.0037 | 0.0029 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0513 | 0.0568 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.0139 | 0.0101 | 0.0094 |
Loa Loa (eye worm) | Na/Ca eXchangers family member | 0.0204 | 0.0183 | 0.018 |
Brugia malayi | Na/Ca eXchangers family member (ncx-4) | 0.0204 | 0.0183 | 0.0431 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 0.0808 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0087 | 0.0037 | 0.0029 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Echinococcus granulosus | sodium:potassium:calcium exchanger | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.3235 | 0.3957 | 0.3955 |
Mycobacterium leprae | Probable ionic transporter integral membrane protein ChaA | 0.0204 | 0.0183 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0052 | 0.0048 |
Onchocerca volvulus | 0.0091 | 0.0043 | 0.0405 | |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0324 | 0.0333 | 0.0329 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.0139 | 0.0101 | 1 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0007 | 0.0054 |
Toxoplasma gondii | manganese resistance 1 protein, putative | 0.0204 | 0.0183 | 1 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0652 | 0.0741 | 0.1845 |
Loa Loa (eye worm) | hypothetical protein | 0.0375 | 0.0395 | 0.0392 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger | 0.0204 | 0.0183 | 0.0176 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.0052 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.1064 | 0.1253 | 0.7184 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Plasmodium vivax | cation/H+ antiporter, putative | 0.0204 | 0.0183 | 0.1693 |
Onchocerca volvulus | 0.0178 | 0.0151 | 0.7789 | |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.1064 | 0.1253 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0178 | 0.0151 | 0.0143 |
Treponema pallidum | hypothetical protein | 0.0204 | 0.0183 | 0.5 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.0139 | 0.0101 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.1064 | 0.1253 | 0.7184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.0183 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0183 | 0.018 |
Onchocerca volvulus | Putative nachr subunit | 0.0178 | 0.0151 | 0.7789 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.0139 | 0.0101 | 0.0098 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.1064 | 0.1253 | 0.3145 |
Brugia malayi | K+-dependent Na+/Ca+ exchanger related-protein | 0.0204 | 0.0183 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.0222 | 0.0215 |
Mycobacterium tuberculosis | Probable ionic transporter integral membrane protein ChaA | 0.0204 | 0.0183 | 0.5 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | nAChR subunit | 0.0087 | 0.0037 | 0.0029 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0731 | 0.0839 | 0.4597 |
Entamoeba histolytica | sodium/calcium exchanger protein, putative | 0.0204 | 0.0183 | 0.1159 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | ACC-1 protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0087 | 0.0037 | 0.0029 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1427 | 0.1705 | 1 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0087 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.0052 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0013 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | Cation transporter family protein | 0.0178 | 0.0151 | 0.0349 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0324 | 0.0333 | 0.2654 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0091 | 0.0043 | 0.0076 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.1064 | 0.1253 | 0.1247 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0689 | 0.0787 | 0.078 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0689 | 0.0787 | 0.1962 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0847 | 0.0983 | 0.098 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0091 | 0.0043 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0178 | 0.0151 | 0.0349 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.0526 | 0.0584 | 1 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0689 | 0.0787 | 0.078 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0178 | 0.0151 | 0.0349 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0091 | 0.0043 | 0.0039 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0037 | 0.0033 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0356 | 0.0372 | 0.1687 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0178 | 0.0151 | 0.0349 |
Schistosoma mansoni | nAChR subunit | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | transient receptor potential channel | 0.0096 | 0.0048 | 0.004 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.0139 | 0.0101 | 0.0094 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.1032 | 0.1214 | 0.9676 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.0139 | 0.0101 | 0.0485 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0091 | 0.0043 | 0.0035 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0092 | 0.0044 | 0.0036 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0178 | 0.0151 | 0.0143 |
Echinococcus granulosus | sodium:potassium:calcium exchanger 6 | 0.0204 | 0.0183 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0043 | 0.0039 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0096 | 0.0048 | 0.004 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0178 | 0.0151 | 0.0147 |
Echinococcus multilocularis | nAChR subunit | 0.0091 | 0.0043 | 0.0035 |
Schistosoma mansoni | nAChR subunit | 0.0087 | 0.0037 | 0.0029 |
Plasmodium falciparum | cation/H+ antiporter | 0.0204 | 0.0183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0652 | 0.0741 | 0.0738 |
Entamoeba histolytica | hypothetical protein | 0.0847 | 0.0983 | 0.7765 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1427 | 0.1705 | 1 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0139 | 0.0101 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0178 | 0.0151 | 0.0349 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0178 | 0.0151 | 0.0143 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0096 | 0.0048 | 0.004 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.1064 | 0.1253 | 1 |
Brugia malayi | hypothetical protein | 0.0236 | 0.0222 | 0.0531 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0178 | 0.0151 | 0.0147 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0178 | 0.0151 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0178 | 0.0151 | 0.0143 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0178 | 0.0151 | 0.0349 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0356 | 0.0372 | 0.091 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0091 | 0.0043 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0204 | 0.0183 | 0.0176 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Mus musculus | ChEMBL23 | 3560161 | |
Homo sapiens | ChEMBL23 | 3560161 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.