Detailed information for compound 951939

Basic information

Technical information
  • TDR Targets ID: 951939
  • Name: (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-e thyl-6-methylhept-6-en-2-yl]-7-hydroperoxy-10 ,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-do decahydro-1H-cyclopenta[a]phenanthren-3-ol
  • MW: 444.69 | Formula: C29H48O3
  • H donors: 2 H acceptors: 2 LogP: 8.21 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@H](C(=C)C)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2[C@H](OO)C=C2[C@]1(C)CC[C@@H](C2)O)C
  • InChi: 1S/C29H48O3/c1-7-20(18(2)3)9-8-19(4)23-10-11-24-27-25(13-15-29(23,24)6)28(5)14-12-22(30)16-21(28)17-26(27)32-31/h17,19-20,22-27,30-31H,2,7-16H2,1,3-6H3/t19-,20+,22+,23-,24+,25+,26-,27+,28+,29-/m1/s1
  • InChiKey: IVFIIMONFJXEHP-MBUAVKJGSA-N  

Network

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Synonyms

  • (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-ethyl-1,5-dimethyl-hex-5-enyl]-7-hydroperoxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-ethyl-1,5-dimethylhex-5-enyl]-7-hydroperoxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methyl-hept-6-en-2-yl]-7-hydroperoxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0081 0.0717 0.4849
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0341 0.0352
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0096 0.0626
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.002 0.01
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0183 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0183 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0081 0.0717 0.0677
Echinococcus multilocularis geminin 0.0796 0.8801 0.8793
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0341 0.0279
Schistosoma mansoni hypothetical protein 0.0343 0.367 0.374
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0183 1
Brugia malayi Niemann-Pick C1 protein precursor 0.011 0.1036 0.1068
Loa Loa (eye worm) transcription factor SMAD2 0.0108 0.1015 0.1027
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0143 0.1411 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.1225 1
Echinococcus multilocularis expressed conserved protein 0.0103 0.0961 0.0902
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0096 0.0232
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.016 0.0826
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.1225 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0183 1
Brugia malayi hypothetical protein 0.0081 0.0717 0.0739
Plasmodium vivax importin-beta 2, putative 0.0032 0.016 0.8601
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0111 0.0401
Loa Loa (eye worm) hypothetical protein 0.0058 0.0449 0.0442
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0278 0.0222
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Onchocerca volvulus Galectin homolog 0.0877 0.9706 1
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.1225 0.1203
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0159 0.0098
Loa Loa (eye worm) hypothetical protein 0.0493 0.537 0.5524
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0628 0.4186
Loa Loa (eye worm) hypothetical protein 0.0877 0.9706 1
Echinococcus multilocularis Galectin, carbohydrate recognition domain 0.0877 0.9706 0.9704
Loa Loa (eye worm) hypothetical protein 0.0047 0.0329 0.0319
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0628 0.4858
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0278 0.0215
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0096 0.0232
Onchocerca volvulus 0.0264 0.2778 0.2791
Schistosoma mansoni transcription factor LCR-F1 0.0081 0.0717 0.0677
Echinococcus granulosus Galectin carbohydrate recognition domain 0.0877 0.9706 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0065 0.0067
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0329 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0173 0.0113
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0628 0.0584
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0877 0.9706 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0628 0.0584
Loa Loa (eye worm) phosphofructokinase 0.0126 0.1225 0.1243
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0183 1
Plasmodium falciparum importin beta, putative 0.0032 0.016 0.8601
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0092 0.01
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.1225 1
Loa Loa (eye worm) hypothetical protein 0.0877 0.9706 1
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1225 0.8617
Schistosoma mansoni hypothetical protein 0.0045 0.031 0.0255
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0341 0.0287
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1225 0.8617
Echinococcus multilocularis Niemann Pick C1 protein 0.0157 0.1568 0.1513
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0078
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0092 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0173 0.0113
Schistosoma mansoni galectin 0.0877 0.9706 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0173 0.0109
Brugia malayi Galactoside-binding lectin family protein 0.0877 0.9706 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0096 0.072
Loa Loa (eye worm) hypothetical protein 0.0493 0.537 0.5524
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0096 0.0626
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0329 0.0266
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0341 0.0287
Echinococcus multilocularis Protein lozenge 0.0062 0.0497 0.0435
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0096 0.0099
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0092 0.01
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.016 0.0826
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Brugia malayi hypothetical protein 0.0028 0.0111 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1225 0.4275
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0341 0.0287
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0094
Loa Loa (eye worm) MH2 domain-containing protein 0.0108 0.1015 0.1027
Onchocerca volvulus Galectin homolog 0.0877 0.9706 1
Schistosoma mansoni hypothetical protein 0.0796 0.8801 0.9061
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1225 0.4275
Loa Loa (eye worm) hypothetical protein 0.011 0.1036 0.1049
Loa Loa (eye worm) galectin 0.0877 0.9706 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0078
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0183 0.0881
Brugia malayi Galactoside-binding lectin family protein 0.0877 0.9706 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0096 0.072
Echinococcus multilocularis Niemann Pick C1 protein 0.011 0.1036 0.0978
Echinococcus granulosus expressed conserved protein 0.0103 0.0961 0.093
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0173 0.0109
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0065 0.0046
Schistosoma mansoni hypothetical protein 0.0796 0.8801 0.9061
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0877 0.9706 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.1225 0.1243
Brugia malayi Galactoside-binding lectin family protein 0.0877 0.9706 1
Brugia malayi phosphofructokinase 0.0126 0.1225 0.1262
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1225 0.8617
Plasmodium vivax SET domain protein, putative 0.0033 0.0173 0.9388
Loa Loa (eye worm) hypothetical protein 0.0143 0.1411 0.1435
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0628 0.4858
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0111 0.5572
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0078
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0183 1
Brugia malayi hypothetical protein 0.0129 0.1254 0.1292
Echinococcus multilocularis importin subunit beta 1 0.0032 0.016 0.0096
Brugia malayi 6-phosphofructokinase 0.0126 0.1225 0.1262
Entamoeba histolytica hypothetical protein 0.0081 0.0717 0.4849
Echinococcus multilocularis protein patched 0.0047 0.0329 0.0266
Schistosoma mansoni hypothetical protein 0.0081 0.0717 0.0677
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0065 0.2713
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0096 0.027
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0096 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0173 0.0113
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.011 0.1036 0.7218
Echinococcus granulosus snurportin 1 0.0343 0.367 0.374
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.1225 0.1203
Brugia malayi 6-phosphofructokinase 0.0126 0.1225 0.1262
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1225 0.4275
Brugia malayi CHE-14 protein 0.0047 0.0329 0.0339
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.1225 0.1168
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0111 0.5572
Schistosoma mansoni hypothetical protein 0.0045 0.031 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0096 0.0626
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.1055 0.1028
Entamoeba histolytica hypothetical protein 0.0026 0.0092 0.0202
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0183 1
Schistosoma mansoni hypothetical protein 0.0045 0.031 0.0255
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0877 0.9706 1
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.016 0.8081
Loa Loa (eye worm) galectin 0.0877 0.9706 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0096 0.0626
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0111 0.0401
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.1225 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0341 0.0331
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0096 0.027
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0096 0.0232
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0341 0.0279
Onchocerca volvulus 0.0493 0.537 0.5488
Trichomonas vaginalis set domain proteins, putative 0.0264 0.2778 1
Leishmania major importin beta-1 subunit, putative 0.0026 0.0092 0.0234
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0096 0.027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0628 0.4858
Brugia malayi galectin 0.0877 0.9706 1
Brugia malayi galectin 0.0877 0.9706 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0628 0.0627
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0096 0.0626
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0329 0.0274
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0111 0.0401
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0096 0.0626
Echinococcus multilocularis microtubule associated protein 2 0.0768 0.848 0.847
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0183 0.0437
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.1225 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0329 0.0319
Echinococcus multilocularis snurportin 1 0.0343 0.367 0.3629
Brugia malayi RNA, U transporter 1 0.0091 0.0829 0.0854
Onchocerca volvulus 0.0033 0.0173 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Brugia malayi Pre-SET motif family protein 0.0232 0.2416 0.2489
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0329 0.0975
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1225 0.4275
Onchocerca volvulus Huntingtin homolog 0.0129 0.1254 0.1205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0341 0.0287
Loa Loa (eye worm) hypothetical protein 0.0032 0.016 0.0144
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0158
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0628 0.4858
Echinococcus granulosus microtubule associated protein 2 0.0768 0.848 0.8728
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.1225 0.1243
Onchocerca volvulus Huntingtin homolog 0.0129 0.1254 0.1205
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0096 0.0626
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0183 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0065 0.2713
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.1225 1
Echinococcus granulosus Niemann Pick C1 protein 0.011 0.1036 0.1008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0343 0.367 0.3769
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0092 0.0234
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.1225 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0628 0.0647
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0143 0.1411 1
Entamoeba histolytica hypothetical protein 0.0081 0.0717 0.4849
Echinococcus granulosus geminin 0.0796 0.8801 0.9061
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0111 0.3923
Schistosoma mansoni importin beta-1 0.0032 0.016 0.0099
Loa Loa (eye worm) hypothetical protein 0.0129 0.1254 0.1274
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0183 1
Loa Loa (eye worm) hypothetical protein 0.0877 0.9706 1
Loa Loa (eye worm) runx1 0.0062 0.0497 0.0492
Leishmania major hypothetical protein, conserved 0.0028 0.0111 0.0401
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0183 1
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0096 0.0099
Echinococcus granulosus importin subunit beta 1 0.0032 0.016 0.0099
Schistosoma mansoni hypothetical protein 0.0045 0.031 0.0255
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0173 0.0113
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0341 0.0287
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0628 0.0567
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0081 0.0717 0.0657
Loa Loa (eye worm) hypothetical protein 0.0129 0.1254 0.1274
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0183 0.0437
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.2416 0.2473
Mycobacterium ulcerans hypothetical protein 0.0026 0.0096 0.0626
Brugia malayi Galactoside-binding lectin family protein 0.0877 0.9706 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0111 0.5572
Echinococcus multilocularis protein dispatched 1 0.0054 0.0404 0.0342
Echinococcus granulosus Niemann Pick C1 protein 0.0157 0.1568 0.1559
Schistosoma mansoni patched 1 0.0047 0.0329 0.0274
Schistosoma mansoni microtubule-associated protein tau 0.0768 0.848 0.8728
Schistosoma mansoni lozenge 0.0062 0.0497 0.0448
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0173 0.0113
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0173 0.916
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.1225 0.1203
Brugia malayi hypothetical protein 0.0493 0.537 0.5533
Brugia malayi Importin beta-1 subunit 0.0032 0.016 0.0165
Brugia malayi Pre-SET motif family protein 0.0033 0.0173 0.0178
Brugia malayi MH2 domain containing protein 0.0108 0.1015 0.1046
Entamoeba histolytica hypothetical protein 0.0081 0.0717 0.4849

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 0.4 ug ml-1 Cytotoxicity against mouse P388 cells after 3 days by MTT assay ChEMBL. No reference
ED50 (functional) = 0.5 ug ml-1 Cytotoxicity against human A549 cells after 6 days by MTT assay ChEMBL. No reference
ED50 (functional) = 1 ug ml-1 Cytotoxicity against human KB cells after 3 days by MTT assay ChEMBL. No reference
ED50 (functional) = 1 ug ml-1 Cytotoxicity against human HT-29 cells after 6 days by MTT assay ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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