Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0717 | 0.4849 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0341 | 0.0352 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0096 | 0.0626 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.002 | 0.01 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0034 | 0.0183 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0034 | 0.0183 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0081 | 0.0717 | 0.0677 |
Echinococcus multilocularis | geminin | 0.0796 | 0.8801 | 0.8793 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0341 | 0.0279 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.367 | 0.374 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0034 | 0.0183 | 1 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.011 | 0.1036 | 0.1068 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0108 | 0.1015 | 0.1027 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0143 | 0.1411 | 1 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0126 | 0.1225 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.0103 | 0.0961 | 0.0902 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0096 | 0.0232 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.016 | 0.0826 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0126 | 0.1225 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0034 | 0.0183 | 1 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0717 | 0.0739 |
Plasmodium vivax | importin-beta 2, putative | 0.0032 | 0.016 | 0.8601 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0111 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0449 | 0.0442 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0043 | 0.0278 | 0.0222 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Onchocerca volvulus | Galectin homolog | 0.0877 | 0.9706 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1203 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0159 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.537 | 0.5524 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0073 | 0.0628 | 0.4186 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.9706 | 1 |
Echinococcus multilocularis | Galectin, carbohydrate recognition domain | 0.0877 | 0.9706 | 0.9704 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0329 | 0.0319 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0628 | 0.4858 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0043 | 0.0278 | 0.0215 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0096 | 0.0232 |
Onchocerca volvulus | 0.0264 | 0.2778 | 0.2791 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0081 | 0.0717 | 0.0677 |
Echinococcus granulosus | Galectin carbohydrate recognition domain | 0.0877 | 0.9706 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0065 | 0.0067 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0047 | 0.0329 | 0.0274 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0173 | 0.0113 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0628 | 0.0584 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0628 | 0.0584 |
Loa Loa (eye worm) | phosphofructokinase | 0.0126 | 0.1225 | 0.1243 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0034 | 0.0183 | 1 |
Plasmodium falciparum | importin beta, putative | 0.0032 | 0.016 | 0.8601 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0092 | 0.01 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0126 | 0.1225 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.9706 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.8617 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.031 | 0.0255 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0341 | 0.0287 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.8617 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0157 | 0.1568 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0096 | 0.0078 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0092 | 0.01 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0173 | 0.0113 |
Schistosoma mansoni | galectin | 0.0877 | 0.9706 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0173 | 0.0109 |
Brugia malayi | Galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0096 | 0.072 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.537 | 0.5524 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0096 | 0.0626 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0047 | 0.0329 | 0.0266 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0341 | 0.0287 |
Echinococcus multilocularis | Protein lozenge | 0.0062 | 0.0497 | 0.0435 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0096 | 0.0099 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0092 | 0.01 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.016 | 0.0826 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0111 | 0.0114 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.4275 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0341 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0111 | 0.0094 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0108 | 0.1015 | 0.1027 |
Onchocerca volvulus | Galectin homolog | 0.0877 | 0.9706 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0796 | 0.8801 | 0.9061 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.4275 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.1036 | 0.1049 |
Loa Loa (eye worm) | galectin | 0.0877 | 0.9706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0096 | 0.0078 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0034 | 0.0183 | 0.0881 |
Brugia malayi | Galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0096 | 0.072 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.011 | 0.1036 | 0.0978 |
Echinococcus granulosus | expressed conserved protein | 0.0103 | 0.0961 | 0.093 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0173 | 0.0109 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0065 | 0.0046 |
Schistosoma mansoni | hypothetical protein | 0.0796 | 0.8801 | 0.9061 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1243 |
Brugia malayi | Galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Brugia malayi | phosphofructokinase | 0.0126 | 0.1225 | 0.1262 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.8617 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0173 | 0.9388 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.1411 | 0.1435 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0073 | 0.0628 | 0.4858 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0111 | 0.5572 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0096 | 0.0078 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0034 | 0.0183 | 1 |
Brugia malayi | hypothetical protein | 0.0129 | 0.1254 | 0.1292 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0032 | 0.016 | 0.0096 |
Brugia malayi | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1262 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0717 | 0.4849 |
Echinococcus multilocularis | protein patched | 0.0047 | 0.0329 | 0.0266 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0717 | 0.0677 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0065 | 0.2713 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0096 | 0.027 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0096 | 0.0099 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0173 | 0.0113 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.011 | 0.1036 | 0.7218 |
Echinococcus granulosus | snurportin 1 | 0.0343 | 0.367 | 0.374 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0126 | 0.1225 | 0.1203 |
Brugia malayi | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1262 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.4275 |
Brugia malayi | CHE-14 protein | 0.0047 | 0.0329 | 0.0339 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0126 | 0.1225 | 0.1168 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0111 | 0.5572 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.031 | 0.0255 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0096 | 0.0626 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0111 | 0.1055 | 0.1028 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0092 | 0.0202 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0034 | 0.0183 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.031 | 0.0255 |
Loa Loa (eye worm) | galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0032 | 0.016 | 0.8081 |
Loa Loa (eye worm) | galectin | 0.0877 | 0.9706 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0096 | 0.0626 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0111 | 0.0401 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0126 | 0.1225 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0341 | 0.0331 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0096 | 0.027 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0096 | 0.0232 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0341 | 0.0279 |
Onchocerca volvulus | 0.0493 | 0.537 | 0.5488 | |
Trichomonas vaginalis | set domain proteins, putative | 0.0264 | 0.2778 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0092 | 0.0234 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0096 | 0.027 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0628 | 0.4858 |
Brugia malayi | galectin | 0.0877 | 0.9706 | 1 |
Brugia malayi | galectin | 0.0877 | 0.9706 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0628 | 0.0627 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0096 | 0.0626 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0047 | 0.0329 | 0.0274 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0111 | 0.0401 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0096 | 0.0626 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0768 | 0.848 | 0.847 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0126 | 0.1225 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0047 | 0.0329 | 0.0319 |
Echinococcus multilocularis | snurportin 1 | 0.0343 | 0.367 | 0.3629 |
Brugia malayi | RNA, U transporter 1 | 0.0091 | 0.0829 | 0.0854 |
Onchocerca volvulus | 0.0033 | 0.0173 | 0.008 | |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Brugia malayi | Pre-SET motif family protein | 0.0232 | 0.2416 | 0.2489 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0329 | 0.0975 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.1225 | 0.4275 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.1254 | 0.1205 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0341 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.016 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0173 | 0.0158 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0628 | 0.4858 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0768 | 0.848 | 0.8728 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1243 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.1254 | 0.1205 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0096 | 0.0626 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0034 | 0.0183 | 1 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0065 | 0.2713 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0126 | 0.1225 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.011 | 0.1036 | 0.1008 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0343 | 0.367 | 0.3769 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0092 | 0.0234 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0126 | 0.1225 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0073 | 0.0628 | 0.0647 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0143 | 0.1411 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0717 | 0.4849 |
Echinococcus granulosus | geminin | 0.0796 | 0.8801 | 0.9061 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0111 | 0.3923 |
Schistosoma mansoni | importin beta-1 | 0.0032 | 0.016 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.1254 | 0.1274 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0034 | 0.0183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.9706 | 1 |
Loa Loa (eye worm) | runx1 | 0.0062 | 0.0497 | 0.0492 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0111 | 0.0401 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0034 | 0.0183 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0096 | 0.0099 |
Echinococcus granulosus | importin subunit beta 1 | 0.0032 | 0.016 | 0.0099 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.031 | 0.0255 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0173 | 0.0113 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0341 | 0.0287 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0628 | 0.0567 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0081 | 0.0717 | 0.0657 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.1254 | 0.1274 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0183 | 0.0437 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0232 | 0.2416 | 0.2473 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0096 | 0.0626 |
Brugia malayi | Galactoside-binding lectin family protein | 0.0877 | 0.9706 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0111 | 0.5572 |
Echinococcus multilocularis | protein dispatched 1 | 0.0054 | 0.0404 | 0.0342 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0157 | 0.1568 | 0.1559 |
Schistosoma mansoni | patched 1 | 0.0047 | 0.0329 | 0.0274 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0768 | 0.848 | 0.8728 |
Schistosoma mansoni | lozenge | 0.0062 | 0.0497 | 0.0448 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0173 | 0.0113 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0173 | 0.916 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0126 | 0.1225 | 0.1203 |
Brugia malayi | hypothetical protein | 0.0493 | 0.537 | 0.5533 |
Brugia malayi | Importin beta-1 subunit | 0.0032 | 0.016 | 0.0165 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0173 | 0.0178 |
Brugia malayi | MH2 domain containing protein | 0.0108 | 0.1015 | 0.1046 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0717 | 0.4849 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.4 ug ml-1 | Cytotoxicity against mouse P388 cells after 3 days by MTT assay | ChEMBL. | No reference |
ED50 (functional) | = 0.5 ug ml-1 | Cytotoxicity against human A549 cells after 6 days by MTT assay | ChEMBL. | No reference |
ED50 (functional) | = 1 ug ml-1 | Cytotoxicity against human KB cells after 3 days by MTT assay | ChEMBL. | No reference |
ED50 (functional) | = 1 ug ml-1 | Cytotoxicity against human HT-29 cells after 6 days by MTT assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.