Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chromobox protein | 0.0189 | 0.2047 | 0.2047 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0369 | 0.4308 | 0.4308 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0089 | 0.0795 | 0.0795 |
Plasmodium vivax | JmjC domain containing protein | 0.0028 | 0.0025 | 0.5 |
Echinococcus granulosus | tumor suppressor p53 binding protein 1 | 0.0314 | 0.3615 | 0.5923 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0092 | 0.0828 | 0.1358 |
Brugia malayi | mbt repeat family protein | 0.0265 | 0.3004 | 0.58 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0702 | 0.1356 |
Brugia malayi | jmjC domain containing protein | 0.0131 | 0.1324 | 0.2556 |
Loa Loa (eye worm) | hypothetical protein | 0.0359 | 0.4186 | 0.8083 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0109 | 0.1049 | 0.1718 |
Echinococcus multilocularis | histone acetyltransferase myst3 | 0.0039 | 0.0165 | 0.0271 |
Loa Loa (eye worm) | MBCTL1 | 0.0092 | 0.0828 | 0.16 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0702 | 0.1356 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0255 | 0.2874 | 0.4709 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.5179 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0109 | 0.1049 | 0.1718 |
Echinococcus multilocularis | tumor suppressor p53 binding protein 1 | 0.0314 | 0.3615 | 0.5923 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0074 | 0.0608 | 0.0996 |
Toxoplasma gondii | PLU-1 family protein | 0.0042 | 0.0204 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0359 | 0.4186 | 0.5 |
Echinococcus granulosus | chromobox protein 2 | 0.0189 | 0.2047 | 0.3355 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0631 | 0.1219 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0359 | 0.4186 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0359 | 0.4186 | 0.5 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0369 | 0.4308 | 0.7059 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0028 | 0.0025 | 0.5 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0092 | 0.0828 | 0.0828 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.198 | 0.3824 |
Schistosoma mansoni | hypothetical protein | 0.0314 | 0.3615 | 0.3615 |
Brugia malayi | mbt repeat family protein | 0.0438 | 0.5179 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0499 | 0.5951 | 0.9751 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0369 | 0.4308 | 0.7059 |
Schistosoma mansoni | phd finger protein | 0.0039 | 0.0165 | 0.0165 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0511 | 0.6103 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0131 | 0.1324 | 0.2556 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0092 | 0.0828 | 0.16 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0511 | 0.6103 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0255 | 0.2874 | 0.2874 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0089 | 0.0795 | 0.0795 |
Echinococcus multilocularis | chromobox protein 2 | 0.0189 | 0.2047 | 0.3355 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0265 | 0.3004 | 0.58 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0089 | 0.0795 | 0.1303 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0092 | 0.0828 | 0.1358 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0499 | 0.5951 | 0.9751 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0092 | 0.0828 | 0.1358 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0255 | 0.2874 | 0.4709 |
Echinococcus granulosus | histone acetyltransferase myst3 | 0.0039 | 0.0165 | 0.0271 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0438 | 0.5179 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0828 | 0.16 |
Brugia malayi | Cation transporter family protein | 0.0082 | 0.0702 | 0.1356 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0082 | 0.0702 | 0.0702 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0092 | 0.0828 | 0.1358 |
Onchocerca volvulus | 0.0289 | 0.3307 | 0.582 | |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0082 | 0.0702 | 0.0702 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0359 | 0.4186 | 0.8083 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0255 | 0.2874 | 0.2874 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.