Detailed information for compound 974489

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 245.317 | Formula: C15H19NO2
  • H donors: 1 H acceptors: 2 LogP: 3.3 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCNC(=O)C(=O)/C=C/c1ccccc1
  • InChi: 1S/C15H19NO2/c1-2-3-7-12-16-15(18)14(17)11-10-13-8-5-4-6-9-13/h4-6,8-11H,2-3,7,12H2,1H3,(H,16,18)/b11-10+
  • InChiKey: QZONCGFMFKIWAD-ZHACJKMWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis fmrfamide receptor 0.0486 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0486 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.011 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Loa Loa (eye worm) steroid hormone receptor 0.001 0.011 0.011
Echinococcus granulosus peptide allatostatin:somatostatin 0.0486 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.011 0.011
Trypanosoma cruzi hexokinase, putative 0.0257 0.5238 0.5
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0486 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0486 1 1
Brugia malayi putative neuropeptide receptor 0.0486 1 1
Schistosoma mansoni neuropeptide receptor 0.0486 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0486 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0486 1 1
Schistosoma mansoni biogenic amine receptor 0.0486 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.011 0.011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.011 0.011
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0486 1 1
Echinococcus multilocularis hexokinase 0.0257 0.5238 0.5238
Onchocerca volvulus 0.0486 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0486 1 1
Echinococcus multilocularis orexin receptor type 2 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.1598 0.1598
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Trypanosoma brucei hexokinase, putative 0.0257 0.5238 0.5
Echinococcus multilocularis g protein coupled receptor 0.0486 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Schistosoma mansoni opsin-like receptor 0.0486 1 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.011 0.011
Onchocerca volvulus 0.0486 1 1
Brugia malayi neuropeptide F receptor 0.0486 1 1
Echinococcus granulosus cpg binding protein 0.003 0.0529 0.0529
Trypanosoma brucei hexokinase 0.0257 0.5238 0.5
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis g protein coupled receptor 0.0486 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0486 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0486 1 1
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Onchocerca volvulus 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus dnaJ subfamily B 0.0407 0.8361 0.8361
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.011 0.011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.011 0.011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0486 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0486 1 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0486 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.011 0.011
Echinococcus granulosus neuropeptide s receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Brugia malayi AKH receptor 0.0486 1 1
Brugia malayi Serotonin receptor 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.011 0.011
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Schistosoma mansoni hypothetical protein 0.0486 1 1
Brugia malayi Hexokinase family protein 0.0079 0.1553 0.1553
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0486 1 1
Echinococcus granulosus FTZ F1 alpha 0.001 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Echinococcus multilocularis hexokinase 0.0257 0.5238 0.5238
Echinococcus multilocularis neuropeptide FF receptor 2 0.0486 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.011 0.011
Echinococcus granulosus g protein coupled receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0049 0.0049
Brugia malayi putative neuropeptide receptor NPR1 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis FTZ F1 alpha 0.001 0.011 0.011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Brugia malayi Hexokinase family protein 0.0257 0.5238 0.5238
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0036 0.5
Schistosoma mansoni thyroid hormone receptor 0.001 0.011 0.011
Brugia malayi Dopamine receptor protein 2 0.0486 1 1
Brugia malayi steroid hormone receptor 0.001 0.011 0.011
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.011 0.011
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Onchocerca volvulus 0.0029 0.0495 0.0495
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0036 0.5
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.011 0.011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0486 1 1
Brugia malayi neuropeptide F receptor 0.0486 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.011 0.011
Echinococcus multilocularis somatostatin receptor 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Loa Loa (eye worm) hexokinase 0.0161 0.3249 0.3249
Echinococcus granulosus tm gpcr rhodopsin 0.0486 1 1
Schistosoma mansoni cpg binding protein 0.003 0.0529 0.0529
Echinococcus multilocularis hexokinase 0.0257 0.5238 0.5238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Brugia malayi hexokinase 0.0257 0.5238 0.5238
Onchocerca volvulus 0.0486 1 1
Echinococcus multilocularis cpg binding protein 0.003 0.0529 0.0529
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0085 0.0085
Brugia malayi Dopamine receptor protein 1 0.0486 1 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0486 1 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0012 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus serotonin receptor 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.011 0.011
Brugia malayi Dopamine receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.011 0.011
Echinococcus granulosus sex peptide receptor 0.0486 1 1
Echinococcus granulosus hexokinase 0.0257 0.5238 0.5238
Brugia malayi G protein-coupled receptor 0.0486 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.011 0.011
Leishmania major hexokinase, putative 0.0257 0.5238 0.5
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0083 0.0083
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus g-protein coupled receptor 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.011 0.011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Echinococcus multilocularis neuropeptide receptor 0.0486 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.011 0.011
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Onchocerca volvulus Bile acid receptor homolog 0.001 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.011 0.011
Brugia malayi nuclear receptor RXR 0.0005 0.0012 0.0012
Schistosoma mansoni cpg binding protein 0.003 0.0529 0.0529
Trichomonas vaginalis helicase, putative 0.0006 0.0036 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Trypanosoma cruzi hexokinase, putative 0.0257 0.5238 0.5
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.011 0.011
Echinococcus multilocularis dro:myosuppressin receptor 0.0486 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0486 1 1
Loa Loa (eye worm) hexokinase 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Brugia malayi ORL1-like opioid receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Schistosoma mansoni nuclear hormone receptor 0.001 0.011 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0486 1 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0012 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0486 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0486 1 1
Brugia malayi Melatonin receptor type 1A 0.0486 1 1
Brugia malayi hypothetical protein 0.0005 0.0012 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.011 0.011
Echinococcus multilocularis neuropeptide receptor 0.0486 1 1
Echinococcus multilocularis allatostatin A receptor 0.0486 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0085 0.0085
Schistosoma mansoni biogenic amine receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0012 0.0012
Trypanosoma brucei hexokinase 0.0257 0.5238 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.011 0.011
Echinococcus multilocularis serotonin receptor 0.0486 1 1
Schistosoma mansoni amine GPCR 0.0486 1 1
Treponema pallidum hexokinase (hxk) 0.0257 0.5238 0.5
Onchocerca volvulus 0.0486 1 1
Brugia malayi RE15519p 0.0486 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0486 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0486 1 1
Schistosoma mansoni amine GPCR 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0486 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.011 0.011
Brugia malayi hypothetical protein 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0486 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0012 0.0012
Echinococcus multilocularis fmrfamide receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.011 0.011
Brugia malayi Tachykinin-like peptides receptor 99D 0.0486 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0486 1 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0486 1 1
Schistosoma mansoni opsin-like receptor 0.0486 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0049 0.0049
Echinococcus granulosus neuropeptide FF receptor 2 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Onchocerca volvulus Hexokinase homolog 0.0161 0.3249 0.3249
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Onchocerca volvulus 0.001 0.011 0.011
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0486 1 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0486 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0486 1 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0012 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Entamoeba histolytica hexokinase 2 0.0257 0.5238 0.5
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis g protein coupled receptor 0.0486 1 1
Schistosoma mansoni myosin xvIII 0.0486 1 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0049 0.0049
Onchocerca volvulus 0.0257 0.5238 0.5238
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.011 0.011
Onchocerca volvulus 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Schistosoma mansoni thyroid hormone receptor 0.001 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0486 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0486 1 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0486 1 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Brugia malayi G-protein coupled receptor 0.0486 1 1
Leishmania major hexokinase, putative 0.0257 0.5238 0.5
Brugia malayi Steroid receptor seven-up type 2 0.001 0.011 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Echinococcus granulosus hexokinase type 2 0.0257 0.5238 0.5238
Brugia malayi larval opioid receptor 0.0486 1 1
Entamoeba histolytica hexokinase 1 0.0257 0.5238 0.5
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) TYRA-2 protein 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0012 0.0012
Schistosoma mansoni amine GPCR 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus neuropeptide receptor 0.0486 1 1
Echinococcus multilocularis serotonin receptor 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0486 1 1
Schistosoma mansoni opsin-like receptor 0.0486 1 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.011 0.011
Echinococcus multilocularis neuropeptide receptor A26 0.0486 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.011 0.011
Brugia malayi Serotonin receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Echinococcus multilocularis neuropeptide s receptor 0.0486 1 1
Brugia malayi Hexokinase family protein 0.0161 0.3249 0.3249
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0012 0.0012
Schistosoma mansoni cpg binding protein 0.0029 0.0495 0.0495
Plasmodium falciparum hexokinase 0.0257 0.5238 0.5
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Toxoplasma gondii hexokinase 0.0257 0.5238 1
Schistosoma mansoni coup transcription factor 0.001 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Schistosoma mansoni amine GPCR 0.0486 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0486 1 1
Loa Loa (eye worm) hexokinase 0.0079 0.1553 0.1553
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.011 0.011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0486 1 1
Schistosoma mansoni hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hexokinase type II 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis g-protein coupled receptor 0.0486 1 1
Brugia malayi GnHR receptor homolog 0.0486 1 1
Echinococcus granulosus somatostatin receptor 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0486 1 1
Onchocerca volvulus 0.0257 0.5238 0.5238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0486 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0486 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0486 1 1
Echinococcus granulosus allatostatin A receptor 0.0486 1 1
Schistosoma mansoni hypothetical protein 0.0486 1 1
Echinococcus granulosus g protein coupled receptor 0.0486 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0036 0.5
Echinococcus granulosus tachykinin peptides receptor 99D 0.0486 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.011 0.011
Brugia malayi CXXC zinc finger family protein 0.0029 0.0495 0.0495
Echinococcus granulosus neuropeptide receptor A26 0.0486 1 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0486 1 1
Brugia malayi G-protein coupled receptor 0.0486 1 1
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.8361 0.8361
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Schistosoma mansoni neuropeptide receptor 0.0486 1 1
Schistosoma mansoni histamine h1 receptor 0.0486 1 1
Schistosoma mansoni neuropeptide receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Brugia malayi nuclear receptor NHR-88 0.001 0.011 0.011
Brugia malayi ecdysteroid receptor 0.001 0.011 0.011
Echinococcus granulosus neuropeptide receptor 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.011 0.011
Onchocerca volvulus 0.0161 0.3249 0.3249
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Brugia malayi hypothetical protein 0.0005 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Brugia malayi nuclear hormone receptor 0.001 0.011 0.011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0486 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0486 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus fmrfamide receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0486 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0486 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.011 0.011
Brugia malayi hexokinase type II 0.0082 0.1598 0.1598
Onchocerca volvulus 0.0486 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus hypothetical protein 0.0486 1 1
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0085 0.0085
Echinococcus granulosus 7tm_1 domain containing protein 0.0486 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0486 1 1
Schistosoma mansoni neuropeptide receptor 0.0486 1 1
Echinococcus granulosus g protein coupled receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Brugia malayi follicle stimulating hormone receptor 0.0486 1 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0486 1 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0486 1 1
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.011 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.011 0.011
Schistosoma mansoni amine GPCR 0.0486 1 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0486 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.011 0.011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0495 0.0495
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.011 0.011
Echinococcus multilocularis neuropeptide Y receptor 0.0486 1 1
Loa Loa (eye worm) hexokinase 0.0257 0.5238 0.5238
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.011 0.011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0486 1 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0486 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0486 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0175 0.3541 0.3541
Echinococcus granulosus orexin receptor type 2 0.0486 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0486 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0486 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0486 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0486 1 1
Echinococcus granulosus hexokinase 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Echinococcus multilocularis sex peptide receptor 0.0486 1 1
Onchocerca volvulus 0.0486 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus hexokinase 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus multilocularis hexokinase type 2 0.0257 0.5238 0.5238
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0486 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Brugia malayi hypothetical protein 0.0486 1 1
Plasmodium vivax hexokinase, putative 0.0257 0.5238 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0486 1 1
Brugia malayi sulfakinin receptor protein 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0486 1 1
Schistosoma mansoni hypothetical protein 0.0407 0.8361 0.8361
Schistosoma mansoni biogenic amine receptor 0.0486 1 1
Schistosoma mansoni hexokinase 0.0257 0.5238 0.5238
Loa Loa (eye worm) hypothetical protein 0.0486 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0036 0.5
Onchocerca volvulus 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.1598 0.1598
Echinococcus granulosus rhodopsin orphan GPCR 0.0486 1 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0486 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Onchocerca volvulus 0.0486 1 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.011 0.011
Schistosoma mansoni neuropeptide F-like receptor 0.0486 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0486 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0486 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0486 1 1
Schistosoma mansoni adenoreceptor 0.0486 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.1161 0.1161

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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