Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0461 | 1 | 1 |
Echinococcus granulosus | glycogen debranching enzyme | 0.0128 | 0.0966 | 0.0713 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0103 | 0.0273 | 0.5 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0128 | 0.0966 | 0.3764 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0389 | 0.8036 | 0.9312 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0171 | 0.2115 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0461 | 1 | 1 |
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.0128 | 0.0966 | 1 |
Echinococcus multilocularis | glycogen debranching enzyme | 0.0128 | 0.0966 | 0.0713 |
Schistosoma mansoni | alpha-glucosidase | 0.0411 | 0.863 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0103 | 0.0273 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0103 | 0.0273 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0461 | 1 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0103 | 0.0273 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0389 | 0.8036 | 0.7981 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0128 | 0.0966 | 0.3764 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0389 | 0.8036 | 0.7981 |
Toxoplasma gondii | Amylo-alpha-1,6-glucosidase | 0.0128 | 0.0966 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0389 | 0.8036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0966 | 0.0713 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0389 | 0.8036 | 0.7981 |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.0128 | 0.0966 | 0.0713 |
Onchocerca volvulus | 0.0365 | 0.7395 | 0.5 | |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0461 | 1 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0171 | 0.2115 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0411 | 0.863 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.196 | 0.2271 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0389 | 0.8036 | 0.7981 |
Giardia lamblia | 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase | 0.0128 | 0.0966 | 0.5 |
Schistosoma mansoni | alpha glucosidase | 0.0103 | 0.0273 | 0.0316 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.