Target list

Search results for query: Union of (#1, #2, #3, #4, #5, #6, #9)

  • Score for genes in query #1 (plasmodium peptidase): 100
  • Score for genes in query #3 (not in mammals): 50
  • Score for genes in query #9 (plasmodium protease): 100
  • Score for genes in query #4 (essential somewhere): 30
  • Score for genes in query #5 (druggability >0.3): 50
  • Score for genes in query #6 (literature): 30
  • Score for genes in query #2 (has structure): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4737 records found | Showing page 3 of 190 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1470500   OG5_155418   phosphodiesterase delta, putative 180
P. falciparum   PF3D7_0201900   OG5_132376   erythrocyte membrane protein 3 180
P. falciparum   PF3D7_0215000   OG5_129177   acyl-CoA synthetase 180
P. falciparum   PF3D7_0311200   OG5_167026   valine--tRNA ligase, putative 180
P. falciparum   PF3D7_0317200   OG5_147470   cdc2-related protein kinase 4 180
P. falciparum   PF3D7_0410300   OG5_149969   protein phosphatase PPM1, putative 180
P. falciparum   PF3D7_0523100   OG5_127941   mitochondrial-processing peptidase subunit alpha, putative 180
P. falciparum   PF3D7_0615500   OG5_150603   cdc2-related protein kinase 5 180
P. falciparum   PF3D7_0623200   OG5_133183   ferredoxin--NADP reductase 180
P. falciparum   PF3D7_0625300   OG5_160659   DNA polymerase 1, putative 180
P. falciparum   PF3D7_0922400   OG5_131264   para-aminobenzoic acid synthetase 180
P. falciparum   PF3D7_0933600   OG5_127023   mitochondrial-processing peptidase subunit beta, putative 180
P. falciparum   PF3D7_1201600   OG5_173806   NIMA related kinase 3 180
P. falciparum   PF3D7_1205700   OG5_162972   targeted glyoxalase II 180
P. falciparum   PF3D7_1214400   OG5_129667   ER membrane protein complex subunit 6, putative 180
P. falciparum   PF3D7_1238900   OG5_139549   protein kinase 2 180
P. falciparum   PF3D7_1344800   OG5_128535   aspartate carbamoyltransferase 160
P. falciparum   PF3D7_1368800   OG5_127977   DNA repair endonuclease, putative 160
P. falciparum   PF3D7_1008900   OG5_126762   adenylate kinase 160
P. falciparum   PF3D7_1012600   OG5_127152   GMP synthase [glutamine-hydrolyzing] 160
P. falciparum   PF3D7_1017000   OG5_127429   DNA polymerase delta catalytic subunit 160
P. falciparum   PF3D7_1029600   OG5_127245   adenosine deaminase 160
P. falciparum   PF3D7_1034400   OG5_126927   flavoprotein subunit of succinate dehydrogenase 160
P. falciparum   PF3D7_1134700   OG5_127929   DNA-directed RNA polymerase I subunit RPA2, putative 160
P. falciparum   PF3D7_1147500   OG5_128081   protein farnesyltransferase subunit beta 160