Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
993 records found | Showing page 2 of 40 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0085 | OG5_147565 | Possible hydrogenase HycP |
| M. tuberculosis | Rv0086 | OG5_134238 | Possible hydrogenase HycQ |
| M. tuberculosis | Rv0091 | OG5_130719 | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ... |
| M. tuberculosis | Rv0092 | OG5_126855 | Cation transporter P-type ATPase a CtpA |
| M. tuberculosis | Rv0097 | OG5_129515 | Possible oxidoreductase |
| M. tuberculosis | Rv0099 | OG5_163246 | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0112 | OG5_149659 | Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) |
| M. tuberculosis | Rv0114 | OG5_134734 | Possible D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-D-ma ... |
| M. tuberculosis | Rv0115 | OG5_131787 | Possible D-alpha-D-heptose-7-phosphate kinase HddA |
| M. tuberculosis | Rv0118c | OG5_126899 | Probable oxalyl-CoA decarboxylase OxcA |
| M. tuberculosis | Rv0125 | OG5_171368 | Probable serine protease PepA (serine proteinase) (MTB32A) |
| M. tuberculosis | Rv0126 | OG5_126827 | Trehalose synthase TreS |
| M. tuberculosis | Rv0129c | OG5_237839 | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ... |
| M. tuberculosis | Rv0130 | OG5_142681 | Probable 3-hydroxyl-thioester dehydratase |
| M. tuberculosis | Rv0131c | OG5_239106 | Probable acyl-CoA dehydrogenase FadE1 |
| M. tuberculosis | Rv0132c | OG5_146706 | Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. tuberculosis | Rv0133 | OG5_141414 | GCN5-related N-acetyltransferase |
| M. tuberculosis | Rv0134 | OG5_142324 | Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv0136 | OG5_135997 | Probable cytochrome P450 138 Cyp138 |
| M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
| M. tuberculosis | Rv0139 | OG5_136762 | Possible oxidoreductase |
| M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
| M. tuberculosis | Rv0148 | OG5_129142 | Probable short-chain type dehydrogenase/reductase |
| M. tuberculosis | Rv0149 | OG5_130824 | Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) |
| M. tuberculosis | Rv0153c | OG5_132308 | Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) |