Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 3 of 32 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0889c | OG5_208928 | Probable citrate synthase II CitA |
| M. tuberculosis | Rv2498c | OG5_130136 | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citri ... |
| M. tuberculosis | Rv3596c | OG5_126636 | Probable ATP-dependent protease ATP-binding subunit ClpC1 |
| M. tuberculosis | Rv2667 | No group | Possible ATP-dependent protease ATP-binding subunit ClpC2 |
| M. tuberculosis | Rv2457c | OG5_128011 | Probable ATP-dependent CLP protease ATP-binding subunit ClpX |
| M. tuberculosis | Rv3392c | OG5_127897 | Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid s ... |
| M. tuberculosis | Rv0503c | OG5_212436 | Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid s ... |
| M. tuberculosis | Rv1092c | OG5_141174 | Probable pantothenate kinase CoaA (pantothenic acid kinase) |
| M. tuberculosis | Rv1631 | OG5_127254 | Probable dephospho-CoA kinase CoaE (dephosphocoenzyme a kinase) |
| M. tuberculosis | Rv2848c | OG5_132745 | Probable cobyrinic acid A,C-diamide synthase CobB |
| M. tuberculosis | Rv2066 | OG5_135738 | Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine ... |
| M. tuberculosis | Rv2072c | OG5_135539 | Precorrin-6Y C(5,15)-methyltransferase (decarboxylating) CobL |
| M. tuberculosis | Rv2071c | OG5_135370 | Precorrin-3 methylase CobM (precorrin-4 C11-methyltransferase) |
| M. tuberculosis | Rv0806c | OG5_135833 | Possible UDP-glucose-4-epimerase CpsY (galactowaldenase) (UDP-galactose-4-epimer ... |
| M. tuberculosis | Rv0092 | OG5_126855 | Cation transporter P-type ATPase a CtpA |
| M. tuberculosis | Rv1469 | OG5_178624 | Probable cation transporter P-type ATPase D CtpD |
| M. tuberculosis | Rv0908 | OG5_176708 | Probable metal cation transporter ATPase P-type CtpE |
| M. tuberculosis | Rv0425c | OG5_215400 | Possible metal cation transporting P-type ATPase CtpH |
| M. tuberculosis | Rv0969 | OG5_126855 | Probable metal cation transporter P-type ATPase CtpV |
| M. tuberculosis | Rv1758 | OG5_136129 | Probable cutinase Cut1 |
| M. tuberculosis | Rv1620c | OG5_138794 | Probable 'component linked with the assembly of cytochrome' transport transmembr ... |
| M. tuberculosis | Rv2276 | No group | Cytochrome P450 121 Cyp121 |
| M. tuberculosis | Rv0766c | OG5_132455 | Probable cytochrome P450 123 Cyp123 |
| M. tuberculosis | Rv2266 | OG5_132455 | Probable cytochrome P450 124 Cyp124 |
| M. tuberculosis | Rv2268c | OG5_132455 | Probable cytochrome P450 128 Cyp128 |