Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 4 of 32 (records 76-100) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1256c | OG5_132455 | Probable cytochrome P450 130 Cyp130 |
| M. tuberculosis | Rv1394c | OG5_127162 | Probable cytochrome P450 132 Cyp132 |
| M. tuberculosis | Rv0327c | OG5_135997 | Possible cytochrome P450 135A1 Cyp135A1 |
| M. tuberculosis | Rv0568 | OG5_135997 | Possible cytochrome P450 135B1 Cyp135B1 |
| M. tuberculosis | Rv3059 | OG5_158762 | Probable cytochrome P450 136 Cyp136 |
| M. tuberculosis | Rv3685c | OG5_135997 | Probable cytochrome P450 137 Cyp137 |
| M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
| M. tuberculosis | Rv1785c | OG5_132455 | Probable cytochrome P450 143 Cyp143 |
| M. tuberculosis | Rv0764c | OG5_129288 | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lano ... |
| M. tuberculosis | Rv0815c | OG5_127129 | Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfa ... |
| M. tuberculosis | Rv2335 | OG5_128713 | Probable serine acetyltransferase CysE (sat) |
| M. tuberculosis | Rv2392 | OG5_129962 | Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, t ... |
| M. tuberculosis | Rv2334 | OG5_126662 | Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thio ... |
| M. tuberculosis | Rv1336 | OG5_126662 | Cysteine synthase B CysM (CSASE B) (O-phosphoserine sulfhydrylase B) (O-phosphos ... |
| M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... |
| M. tuberculosis | Rv2399c | OG5_129975 | Probable sulfate-transport integral membrane protein ABC transporter CysT |
| M. tuberculosis | Rv2398c | OG5_137861 | Probable sulfate-transport integral membrane protein ABC transporter CysW |
| M. tuberculosis | Rv2911 | OG5_129917 | Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) ... |
| M. tuberculosis | Rv2773c | OG5_131385 | Dihydrodipicolinate reductase DapB (DHPR) |
| M. tuberculosis | Rv1253 | OG5_126984 | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase ... |
| M. tuberculosis | Rv0429c | OG5_128237 | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) |
| M. tuberculosis | Rv1094 | OG5_237738 | Possible acyl-[acyl-carrier protein] desaturase DesA2 (acyl-[ACP] desaturase) (s ... |
| M. tuberculosis | Rv3132c | OG5_153508 | Two component sensor histidine kinase DevS |
| M. tuberculosis | Rv2763c | OG5_128410 | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) |
| M. tuberculosis | Rv2579 | OG5_158622 | Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) |