Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
100 records found | Showing page 3 of 4 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv2378c | No group | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase) |
| M. tuberculosis | Rv3341 | OG5_131823 | Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (hom ... |
| M. tuberculosis | Rv3112 | OG5_132863 | Probable molybdenum cofactor biosynthesis protein D MoaD1 (molybdopterin convert ... |
| M. tuberculosis | Rv3323c | OG5_128296 | Probable MoaD-MoaE fusion protein MoaX |
| M. tuberculosis | Rv0091 | OG5_130719 | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ... |
| M. tuberculosis | Rv0482 | OG5_131886 | Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramat ... |
| M. tuberculosis | Rv2157c | OG5_132578 | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-al ... |
| M. tuberculosis | Rv2156c | OG5_131597 | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX |
| M. tuberculosis | Rv1594 | OG5_132446 | Probable quinolinate synthetase NadA |
| M. tuberculosis | Rv1162 | OG5_140152 | Probable respiratory nitrate reductase (beta chain) NarH |
| M. tuberculosis | Rv1854c | OG5_126960 | Probable NADH dehydrogenase Ndh |
| M. tuberculosis | Rv0392c | OG5_126960 | Probable membrane NADH dehydrogenase NdhA |
| M. tuberculosis | Rv2391 | OG5_132911 | Ferredoxin-dependent sulfite reductase SirA |
| M. tuberculosis | Rv3052c | OG5_143153 | Probable NrdI protein |
| M. tuberculosis | Rv3490 | OG5_129327 | Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosph ... |
| M. tuberculosis | Rv2225 | OG5_129046 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB |
| M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... |
| M. tuberculosis | Rv3601c | OG5_134769 | Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase ... |
| M. tuberculosis | Rv2612c | OG5_135089 | PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglycerol--inositol- ... |
| M. tuberculosis | Rv2351c | OG5_131170 | Membrane-associated phospholipase C 1 PlcA (MTP40 antigen) |
| M. tuberculosis | Rv2350c | OG5_131170 | Membrane-associated phospholipase C 2 PlcB |
| M. tuberculosis | Rv2349c | OG5_131170 | Probable phospholipase C 3 PlcC |
| M. tuberculosis | Rv2043c | OG5_127752 | Pyrazinamidase/nicotinamidase PncA (PZase) |
| M. tuberculosis | Rv1127c | OG5_127082 | Probable pyruvate, phosphate dikinase PpdK |
| M. tuberculosis | Rv2702 | OG5_164841 | Polyphosphate glucokinase PpgK (polyphosphate-glucose phosphotransferase) |