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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 3 of 91 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... | 332 |
M. tuberculosis | Rv3371 | OG5_133846 | Possible triacylglycerol synthase (diacylglycerol acyltransferase) | 332 |
M. tuberculosis | Rv3484 | OG5_213861 | Possible conserved protein CpsA | 331 |
M. tuberculosis | Rv3380c | OG5_128670 | Probable transposase | 331 |
M. tuberculosis | Rv1405c | OG5_176030 | Putative methyltransferase | 327 |
M. tuberculosis | Rv3776 | OG5_166864 | Conserved hypothetical protein | 326 |
M. tuberculosis | Rv3801c | OG5_127582 | Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... | 325 |
M. tuberculosis | Rv2358 | OG5_155588 | Probable transcriptional regulatory protein SmtB (probably ArsR-family) | 324 |
M. tuberculosis | Rv0834c | OG5_129879 | PE-PGRS family protein PE_PGRS14 | 322 |
M. tuberculosis | Rv1806 | OG5_132981 | PE family protein PE20 | 322 |
M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase | 322 |
M. tuberculosis | Rv2631 | OG5_127467 | Conserved hypothetical protein | 322 |
M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... | 321 |
M. tuberculosis | Rv0559c | OG5_237782 | Possible conserved secreted protein | 321 |
M. tuberculosis | Rv1894c | OG5_141344 | Conserved hypothetical protein | 321 |
M. tuberculosis | Rv0752c | OG5_136059 | Probable acyl-CoA dehydrogenase FadE9 | 320 |
M. tuberculosis | Rv0827c | OG5_129305 | Metal sensor transcriptional regulator KmtR (ArsR-SmtB family) | 319 |
M. tuberculosis | Rv3572 | No group | Unknown protein | 318 |
M. tuberculosis | Rv2500c | OG5_128729 | Possible acyl-CoA dehydrogenase FadE19 (MMGC) | 315 |
M. tuberculosis | Rv3437 | No group | Possible conserved transmembrane protein | 314 |
M. tuberculosis | Rv2466c | OG5_237696 | Conserved protein | 312 |
M. tuberculosis | Rv3615c | OG5_237582 | ESX-1 secretion-associated protein EspC | 308 |
M. tuberculosis | Rv3406 | OG5_129515 | Probable dioxygenase | 307 |
M. tuberculosis | Rv2359 | OG5_130371 | Probable zinc uptake regulation protein Zur | 304 |
M. tuberculosis | Rv0455c | OG5_237795 | Conserved protein | 301 |