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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0885 | OG5_237762 | Conserved hypothetical protein | 597 |
M. tuberculosis | Rv3290c | OG5_129508 | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysi ... | 583 |
M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) | 571 |
M. tuberculosis | Rv3340 | OG5_130839 | Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetyl ... | 536 |
M. tuberculosis | Rv2629 | No group | Conserved protein | 524 |
M. tuberculosis | Rv2004c | OG5_142650 | Conserved protein | 520 |
M. tuberculosis | Rv2626c | OG5_130004 | Hypoxic response protein 1 Hrp1 | 495 |
M. tuberculosis | Rv0275c | OG5_179227 | Possible transcriptional regulatory protein (possibly TetR-family) | 478 |
M. tuberculosis | Rv2628 | No group | Hypothetical protein | 476 |
M. tuberculosis | Rv2830c | No group | Possible antitoxin VapB22 | 473 |
M. tuberculosis | Rv2035 | No group | Conserved hypothetical protein | 469 |
M. tuberculosis | Rv2623 | OG5_126997 | Universal stress protein family protein TB31.7 | 456 |
M. tuberculosis | Rv2630 | No group | Hypothetical protein | 454 |
M. tuberculosis | Rv2497c | OG5_128261 | Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA | 453 |
M. tuberculosis | Rv2115c | OG5_237684 | Mycobacterial proteasome ATPase Mpa | 451 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 448 |
M. tuberculosis | Rv2711 | OG5_132027 | Iron-dependent repressor and activator IdeR | 440 |
M. tuberculosis | Rv2624c | OG5_126997 | Universal stress protein family protein | 440 |
M. tuberculosis | Rv2627c | OG5_239110 | Conserved protein | 440 |
M. tuberculosis | Rv3131 | OG5_179425 | Conserved protein | 435 |
M. tuberculosis | Rv1813c | OG5_239134 | Conserved hypothetical protein | 426 |
M. tuberculosis | Rv3126c | No group | Hypothetical protein | 421 |
M. tuberculosis | Rv3130c | OG5_133846 | Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1 | 412 |
M. tuberculosis | Rv2496c | OG5_128323 | Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB | 404 |
M. tuberculosis | Rv3841 | OG5_127547 | Bacterioferritin BfrB | 399 |