Target list

Search results for query: Weighted ranking of Pfa targets for PLOS-NTD

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #84 (Mtb not in humans (now searched on pfa)): 25
  • Score for genes in query #82 (Mtb PDB (now searched on pfa)): 50
  • Score for genes in query #90 (Mtb all proteins (now searched on pfa)): 1
  • Score for genes in query #80 (Mtb mwt <100kDa (now searched on pfa)): 20
  • Score for genes in query #85 (Mtb any genetic validation (now searched on pfa)): 50
  • Score for genes in query #89 (Mtb assayable (now searched on pfa)): 35
  • Score for genes in query #93 (Pfa in Pvi): 25
  • Score for genes in query #87 (Mtb dindex >=0.6 (now searched on pfa)): 35
  • Score for genes in query #79 (Mtb Pubmed (now searched on pfa)): 35
  • Score for genes in query #81 (Mtb no TM domain (now searched on pfa)): 20
  • Score for genes in query #88 (Mtb Compd desirability >0.3 (now searched on pfa)): 35
  • Score for genes in query #86 (Mtb any essentiality evidence (now searched on pfa)): 50
  • Score for genes in query #83 (Mtb modbase (now searched on pfa)): 30
  • Score for genes in query #78 (Mtb enz (EC + func. Categ.) (now searched on pfa)): 100

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 192 of 193 (records 4776-4800) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0316700   OG5_127473   protein YOP1, putative 46
P. falciparum   PF3D7_1101600   OG5_151956   exported protein family 3 46
P. falciparum   PF3D7_0324300   OG5_149180   exported protein family 4 46
P. falciparum   PF3D7_0324600   OG5_132200   stevor 46
P. falciparum   PF3D7_0402600   OG5_132200   stevor 46
P. falciparum   PF3D7_0414300   OG5_130486   Rab5-interacting protein, putative 46
P. falciparum   PF3D7_0425500   OG5_132200   stevor 46
P. falciparum   PF3D7_0425700   OG5_126825   rifin 46
P. falciparum   PF3D7_0504900   OG5_128960   conserved protein, unknown function 46
P. falciparum   PF3D7_0526900   OG5_127696   transmembrane emp24 domain-containing protein, putative 46
P. falciparum   PF3D7_0528400   OG5_126830   palmitoyltransferase DHHC7 46
P. falciparum   PF3D7_0601900   OG5_205528   conserved Plasmodium protein, unknown function 46
P. falciparum   PF3D7_0611000   OG5_128091   SNARE associated Golgi protein, putative 46
P. falciparum   PF3D7_0613200   OG5_205346   conserved Plasmodium protein, unknown function 46
P. falciparum   PF3D7_0617700   OG5_126825   rifin 46
P. falciparum   PF3D7_0631600   OG5_149180   exported protein family 4 46
P. falciparum   PF3D7_0632700   OG5_126825   rifin 46
P. falciparum   PF3D7_0901700   OG5_149180   Plasmodium exported protein (hyp5), unknown function 46
P. falciparum   PF3D7_0903100   OG5_127650   protein RER1, putative 46
P. falciparum   PF3D7_0922300   OG5_162005   conserved Plasmodium protein, unknown function 46
P. falciparum   PF3D7_1204900     No group probable protein, unknown function 46
P. falciparum   PF3D7_1218400   OG5_129097   triose or hexose phosphate/phosphate translocator, putative 46
P. falciparum   PF3D7_1219800   OG5_205417   conserved Plasmodium protein, unknown function 46
P. falciparum   PF3D7_1240100     No group early transcribed membrane protein 12 46
P. falciparum   PF3D7_1248500   OG5_126826   bax inhibitor 1, putative 46

Showing page 192 (records 4776-4800) of 193