Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
253 records found | Showing page 3 of 11 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| P. falciparum | PF3D7_0605600 | OG5_133897 | nucleoside diphosphate kinase, putative |
| P. falciparum | PF3D7_0605900 | OG5_126732 | long chain polyunsaturated fatty acid elongation enzyme, putative |
| P. falciparum | PF3D7_0608800 | OG5_126982 | ornithine aminotransferase |
| P. falciparum | PF3D7_0610800 | OG5_126720 | transketolase |
| P. falciparum | PF3D7_0615100 | OG5_130466 | enoyl-acyl carrier reductase |
| P. falciparum | PF3D7_0616000 | OG5_127394 | pyridoxal kinase |
| P. falciparum | PF3D7_0618500 | OG5_126911 | malate dehydrogenase |
| P. falciparum | PF3D7_0619500 | OG5_126609 | acyl-CoA synthetase |
| P. falciparum | PF3D7_0623200 | OG5_133183 | ferredoxin--NADP reductase |
| P. falciparum | PF3D7_0623500 | OG5_158563 | superoxide dismutase [Fe] |
| P. falciparum | PF3D7_0624000 | OG5_126743 | hexokinase |
| P. falciparum | PF3D7_0626800 | OG5_126685 | pyruvate kinase |
| P. falciparum | PF3D7_0627800 | OG5_126680 | acetyl-CoA synthetase, putative |
| P. falciparum | PF3D7_0630700 | OG5_167299 | bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, putative |
| P. falciparum | PF3D7_0702200 | OG5_147528 | lysophospholipase, putative |
| P. falciparum | PF3D7_0708100 | OG5_127691 | DNA-directed RNA polymerases I, II, and III subunit RPABC5, putative |
| P. falciparum | PF3D7_0709000 | OG5_133154 | chloroquine resistance transporter |
| P. falciparum | PF3D7_0709700 | OG5_141341 | prodrug activation and resistance esterase |
| P. falciparum | PF3D7_0719200 | OG5_127026 | NIMA related kinase 4 |
| P. falciparum | PF3D7_0731600 | OG5_136613 | acyl-CoA synthetase |
| P. falciparum | PF3D7_0801800 | OG5_127555 | mannose-6-phosphate isomerase, putative |
| P. falciparum | PF3D7_0804400 | OG5_156787 | methionine aminopeptidase 1c, putative |
| P. falciparum | PF3D7_0804800 | OG5_129014 | peptidyl-prolyl cis-trans isomerase |
| P. falciparum | PF3D7_0808200 | OG5_133546 | plasmepsin X |
| P. falciparum | PF3D7_0810800 | OG5_128803 | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase |