Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
1043 records found | Showing page 40 of 42 (records 976-1000) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3609c | OG5_127507 | GTP cyclohydrolase I FolE (GTP-ch-I) |
| M. tuberculosis | Rv3610c | OG5_126616 | Membrane-bound protease FtsH (cell division protein) |
| M. tuberculosis | Rv3624c | OG5_127374 | Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanth ... |
| M. tuberculosis | Rv3625c | OG5_131037 | Possible cell cycle protein MesJ |
| M. tuberculosis | Rv3627c | OG5_138822 | Conserved protein |
| M. tuberculosis | Rv3628 | OG5_128875 | Inorganic pyrophosphatase Ppa (pyrophosphate phospho-hydrolase) (PPASE) (inorgan ... |
| M. tuberculosis | Rv3635 | OG5_237565 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv3644c | OG5_134682 | Possible DNA polymerase |
| M. tuberculosis | Rv3646c | OG5_126736 | DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) ( ... |
| M. tuberculosis | Rv3648c | OG5_126866 | Probable cold shock protein A CspA |
| M. tuberculosis | Rv3658c | OG5_140201 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv3666c | OG5_131268 | Probable periplasmic dipeptide-binding lipoprotein DppA |
| M. tuberculosis | Rv3667 | OG5_126680 | Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) ( ... |
| M. tuberculosis | Rv3672c | OG5_127325 | Conserved hypothetical protein |
| M. tuberculosis | Rv3674c | OG5_126913 | Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lya ... |
| M. tuberculosis | Rv3676 | OG5_130305 | Transcriptional regulatory protein Crp (Crp/Fnr-family) |
| M. tuberculosis | Rv3679 | OG5_208940 | Probable anion transporter ATPase |
| M. tuberculosis | Rv3683 | OG5_131163 | Conserved protein |
| M. tuberculosis | Rv3692 | OG5_130615 | Probable methanol dehydrogenase transcriptional regulatory protein MoxR2 |
| M. tuberculosis | Rv3696c | OG5_126746 | Probable glycerol kinase GlpK (ATP:glycerol 3-phosphotransferase) (glycerokinase ... |
| M. tuberculosis | Rv3700c | OG5_127282 | Conserved hypothetical protein |
| M. tuberculosis | Rv3701c | OG5_130034 | Conserved hypothetical protein |
| M. tuberculosis | Rv3703c | OG5_130034 | Conserved hypothetical protein |
| M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... |
| M. tuberculosis | Rv3721c | OG5_127045 | DNA polymerase III (subunit gamma/tau) DnaZ/X |