Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
394 records found | Showing page 2 of 16 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0213c | OG5_133749 | Possible methyltransferase (methylase) |
| M. tuberculosis | Rv0220 | OG5_130169 | Probable esterase LipC |
| M. tuberculosis | Rv0222 | OG5_169926 | Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0223c | OG5_137356 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0228 | OG5_176236 | Probable integral membrane acyltransferase |
| M. tuberculosis | Rv0247c | No group | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0248c | OG5_126927 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0270 | OG5_126609 | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
| M. tuberculosis | Rv0291 | OG5_149677 | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like prot ... |
| M. tuberculosis | Rv0294 | OG5_147019 | Probable trans-aconitate methyltransferase Tam |
| M. tuberculosis | Rv0315 | OG5_130926 | Possible beta-1,3-glucanase precursor |
| M. tuberculosis | Rv0316 | No group | Possible muconolactone isomerase |
| M. tuberculosis | Rv0319 | OG5_128512 | Probable pyrrolidone-carboxylate peptidase Pcp (5-oxoprolyl-peptidase) (pyroglut ... |
| M. tuberculosis | Rv0334 | OG5_131815 | Alpha-D-glucose-1-phosphate thymidylyltransferase RmlA (dTDP-glucose synthase) ( ... |
| M. tuberculosis | Rv0350 | OG5_126744 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa prote ... |
| M. tuberculosis | Rv0363c | OG5_131639 | Probable fructose-bisphosphate aldolase Fba |
| M. tuberculosis | Rv0373c | OG5_127252 | Probable carbon monoxyde dehydrogenase (large chain) |
| M. tuberculosis | Rv0374c | OG5_134409 | Probable carbon monoxyde dehydrogenase (small chain) |
| M. tuberculosis | Rv0392c | OG5_126960 | Probable membrane NADH dehydrogenase NdhA |
| M. tuberculosis | Rv0404 | OG5_126609 | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... |
| M. tuberculosis | Rv0409 | OG5_130287 | Probable acetate kinase AckA (acetokinase) |
| M. tuberculosis | Rv0410c | OG5_210922 | Serine/threonine-protein kinase PknG (protein kinase G) (STPK G) |
| M. tuberculosis | Rv0418 | OG5_133965 | Probable lipoprotein aminopeptidase LpqL |
| M. tuberculosis | Rv0419 | No group | Possible lipoprotein peptidase LpqM |
| M. tuberculosis | Rv0425c | OG5_215400 | Possible metal cation transporting P-type ATPase CtpH |