Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
394 records found | Showing page 3 of 16 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0427c | OG5_126768 | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP e ... |
| M. tuberculosis | Rv0429c | OG5_128237 | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) |
| M. tuberculosis | Rv0432 | OG5_127584 | Periplasmic superoxide dismutase [Cu-Zn] SodC |
| M. tuberculosis | Rv0456c | No group | enoyl-CoA hydratase EchA2 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crot ... |
| M. tuberculosis | Rv0458 | OG5_126638 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv0486 | OG5_135052 | Glycosyltransferase MshA |
| M. tuberculosis | Rv0500 | OG5_126801 | Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) |
| M. tuberculosis | Rv0505c | OG5_138823 | Possible phosphoserine phosphatase SerB1 (PSP) (O-phosphoserine phosphohydrolase ... |
| M. tuberculosis | Rv0517 | OG5_162561 | Possible membrane acyltransferase |
| M. tuberculosis | Rv0520 | OG5_171559 | POSSIBLE METHYLTRANSFERASE/METHYLASE (FRAGMENT) |
| M. tuberculosis | Rv0521 | No group | POSSIBLE METHYLTRANSFERASE/METHYLASE (FRAGMENT) |
| M. tuberculosis | Rv0533c | OG5_129509 | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase I ... |
| M. tuberculosis | Rv0536 | OG5_130678 | Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epime ... |
| M. tuberculosis | Rv0551c | No group | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
| M. tuberculosis | Rv0558 | OG5_127211 | Probable ubiquinone/menaquinone biosynthesis methyltransferase MenH (2-heptapren ... |
| M. tuberculosis | Rv0560c | OG5_139036 | Possible benzoquinone methyltransferase (methylase) |
| M. tuberculosis | Rv0563 | OG5_131984 | Probable protease transmembrane protein heat shock protein HtpX |
| M. tuberculosis | Rv0619 | OG5_129227 | Probable galactose-1-phosphate uridylyltransferase GalTb [second part] |
| M. tuberculosis | Rv0620 | OG5_129789 | Probable galactokinase GalK (galactose kinase) |
| M. tuberculosis | Rv0630c | OG5_140510 | Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exo ... |
| M. tuberculosis | Rv0631c | OG5_141789 | Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(e ... |
| M. tuberculosis | Rv0632c | OG5_131454 | Probable enoyl-CoA hydratase EchA3 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0642c | OG5_212435 | Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (h ... |
| M. tuberculosis | Rv0643c | No group | Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (h ... |