Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
1043 records found | Showing page 2 of 42 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv0103c | OG5_126855 | Probable cation-transporter P-type ATPase B CtpB |
M. tuberculosis | Rv0104 | OG5_126950 | Conserved hypothetical protein |
M. tuberculosis | Rv0105c | OG5_130709 | 50S ribosomal protein L28-1 RpmB1 |
M. tuberculosis | Rv0107c | OG5_215400 | Probable cation-transporter ATPase I CtpI |
M. tuberculosis | Rv0110 | OG5_127224 | Probable conserved integral membrane protein |
M. tuberculosis | Rv0112 | OG5_149659 | Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) |
M. tuberculosis | Rv0113 | OG5_133989 | Probable sedoheptulose-7-phosphate isomerase GmhA (phosphoheptose isomerase) |
M. tuberculosis | Rv0118c | OG5_126899 | Probable oxalyl-CoA decarboxylase OxcA |
M. tuberculosis | Rv0119 | OG5_126609 | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
M. tuberculosis | Rv0125 | OG5_171368 | Probable serine protease PepA (serine proteinase) (MTB32A) |
M. tuberculosis | Rv0127 | OG5_239105 | Maltokinase Mak |
M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
M. tuberculosis | Rv0148 | OG5_129142 | Probable short-chain type dehydrogenase/reductase |
M. tuberculosis | Rv0155 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic pa ... |
M. tuberculosis | Rv0157 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] ... |
M. tuberculosis | Rv0162c | OG5_127257 | Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 |
M. tuberculosis | Rv0166 | OG5_126609 | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
M. tuberculosis | Rv0167 | OG5_130961 | Conserved integral membrane protein YrbE1A |
M. tuberculosis | Rv0183 | OG5_127037 | Possible lysophospholipase |
M. tuberculosis | Rv0187 | OG5_128394 | Probable O-methyltransferase |
M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
M. tuberculosis | Rv0192 | OG5_204773 | Conserved hypothetical protein |
M. tuberculosis | Rv0194 | OG5_126596 | Probable transmembrane multidrug efflux pump |
M. tuberculosis | Rv0198c | OG5_127344 | Probable zinc metalloprotease Zmp1 |