Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 314 of 330 (records 7826-7850) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.26.1130   OG5_183708   hypothetical protein, unknown function 46
L. major   LmjF.24.1250   OG5_157940   amastin-like surface protein-like protein 46
L. major   LmjF.35.0680   OG5_184074   hypothetical protein, conserved 46
L. major   LmjF.08.0610     No group hypothetical protein, conserved 46
L. major   LmjF.36.2120   OG5_184143   hypothetical protein, conserved 46
L. major   LmjF.08.0840   OG5_130987   amastin-like protein 46
L. major   LmjF.21.0861   OG5_173477   hypothetical protein 46
L. major   LmjF.18.1410   OG5_183454   hypothetical protein, conserved 46
L. major   LmjF.34.0980   OG5_180152   amastin-like protein 46
L. major   LmjF.05.0770   OG5_183173   hypothetical protein, unknown function 46
L. major   LmjF.26.1840   OG5_183722   hypothetical protein, conserved 46
L. major   LmjF.10.0715   OG5_127000   amino acid transporter, putative 46
L. major   LmjF.35.2510   OG5_130002   hypothetical protein, conserved 46
L. major   LmjF.31.1860   OG5_183913   hypothetical protein, unknown function 46
L. major   LmjF.27.2080   OG5_183746   hypothetical protein, unknown function 46
L. major   LmjF.27.0660   OG5_169639   hypothetical protein, conserved 46
L. major   LmjF.30.1810   OG5_128968   hypothetical protein, conserved 46
L. major   LmjF.30.1160   OG5_183850   hypothetical protein, conserved 46
L. major   LmjF.04.1090   OG5_151436   hypothetical protein, conserved 46
L. major   LmjF.06.0900   OG5_173448   hypothetical protein, conserved 46
L. major   LmjF.23.0840   OG5_183615   hypothetical protein, unknown function 46
L. major   LmjF.26.1670   OG5_128204   fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 46
L. major   LmjF.08.0820   OG5_132980   amastin-like protein 46
L. major   LmjF.01.0335   OG5_128371   hypothetical protein, conserved 46
L. major   LmjF.36.6610   OG5_162727   hypothetical protein, conserved 46

Showing page 314 (records 7826-7850) of 330