Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

| Modify weights! (moves query to your history allowing re-weight functionality)
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
Show: all curated predicted compounds associated with these genes.

Compounds have been manually associated with targets based on literature curation (curated), and transitively associated with direct orthologs (predicted). Please note that a link between a compound and a target does not imply an outstanding activity (e.g. inhibition). In many cases the association serves the only purpose of showing that e.g. "compound X" has been tested against "target Y", even if there was no detectable activity in the assay. Information about each assay and its outcome is available for each compound.

8243 records found | Showing page 330 of 330 (records 8226-8243) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.02.0420   OG5_166671   hypothetical protein, conserved 26
L. major   LmjF.34.2070   OG5_138564   hypothetical protein, conserved 26
L. major   LmjF.07.0550   OG5_183208   cysteine peptidase B (CPB) 26
L. major   LmjF.05.0910   OG5_183176   hypothetical protein, conserved 26
L. major   LmjF.35.2960   OG5_163862   hypothetical protein, conserved 21
L. major   LmjF.04.0180   OG5_126560   surface antigen-like protein 21
L. major   LmjF.14.0070   OG5_181454   hypothetical protein, unknown function 21
L. major   LmjF.35.5370   OG5_128654   diacylglycerol kinase-like protein 21
L. major   LmjF.36.4870   OG5_127038   hypothetical protein, conserved 21
L. major   LmjF.25.1880   OG5_128756   hypothetical protein, unknown function 21
L. major   LmjF.04.0190   OG5_128550   surface antigen-like protein 21
L. major   LmjF.19.0310   OG5_128045   membrane protein, putative 21
L. major   LmjF.36.5500   OG5_127242   hypothetical protein, conserved 21
L. major   LmjF.22.0410   OG5_131544   hypothetical protein, conserved 1
L. major   LmjF.02.0330   OG5_204138   glycosyl transferase, putative 1
L. major   LmjF.18.0110   OG5_164197   hypothetical protein, conserved 1
L. major   LmjF.34.1270   OG5_180790   hypothetical protein, conserved 1
L. major   LmjF.36.3340   OG5_164200   hypothetical transmembrane protein 1

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TDR Targets Development Release v6, Revision: 1403 (05.Dec.2018)
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