Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 315 of 330 (records 7851-7875) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.29.0650   OG5_180982   phosphate transporter, putative 46
L. major   LmjF.35.0920   OG5_184077   hypothetical protein, conserved 46
L. major   LmjF.03.0850   OG5_183134   hypothetical protein, conserved 46
L. major   LmjF.21.1390   OG5_136877   zinc finger domain-like protein 46
L. major   LmjF.12.0995   OG5_154537   hypothetical protein 46
L. major   LmjF.31.2240   OG5_204244   hypothetical protein, unknown function 46
L. major   LmjF.11.1200   OG5_126850   hypothetical protein, conserved 46
L. major   LmjF.31.1420   OG5_183903   hypothetical protein, conserved 46
L. major   LmjF.12.0160   OG5_129144   dolichyl-P-Man:GDP-Man5GlcNAc2-PP-dolichyl alpha-1,2-mannosyltransferase, putati ... 46
L. major   LmjF.31.1950   OG5_183916   hypothetical protein, conserved 46
L. major   LmjF.19.1490   OG5_129243   hypothetical protein, conserved 46
L. major   LmjF.28.0130   OG5_166745   hypothetical protein, conserved 46
L. major   LmjF.31.2140   OG5_183922   hypothetical protein, unknown function 46
L. major   LmjF.30.0390   OG5_183843   hypothetical protein, unknown function 46
L. major   LmjF.26.1690   OG5_128204   fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 46
L. major   LmjF.26.0540   OG5_183699   hypothetical protein, conserved 46
L. major   LmjF.31.0870   OG5_142921   amino acid permease 3 46
L. major   LmjF.34.1640   OG5_130729   amastin-like surface protein, putative 46
L. major   LmjF.24.0380   OG5_180406   ppg3-related protein-like protein 46
L. major   LmjF.21.1220   OG5_147390   hypothetical protein, conserved 46
L. major   LmjF.35.2180   OG5_184090   hypothetical protein, conserved 46
L. major   LmjF.21.1000   OG5_183575   hypothetical protein, unknown function 46
L. major   LmjF.34.1600   OG5_130729   amastin-like surface protein, putative 46
L. major   LmjF.09.1240   OG5_144294   hypothetical protein, conserved 46
L. major   LmjF.25.1680   OG5_183689   hypothetical protein, unknown function 46

Showing page 315 (records 7851-7875) of 330