Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 316 of 330 (records 7876-7900) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.27.2380   OG5_183753   hypothetical protein, unknown function 46
L. major   LmjF.36.5220   OG5_184175   hypothetical protein, conserved 46
L. major   LmjF.12.1000   OG5_173557   promastigote surface antigen protein 2 PSA2 46
L. major   LmjF.25.0660   OG5_166734   hypothetical protein, conserved 46
L. major   LmjF.18.0710   OG5_183445   hypothetical protein, unknown function 46
L. major   LmjF.35.1800   OG5_130512   hypothetical protein, conserved 46
L. major   LmjF.12.0200   OG5_183310   hypothetical protein, unknown function 46
L. major   LmjF.25.2240   OG5_183682   hypothetical protein, conserved 46
L. major   LmjF.04.0220   OG5_183139   hypothetical protein 46
L. major   LmjF.31.3150   OG5_129754   hypothetical protein, conserved 46
L. major   LmjF.19.1100   OG5_183473   hypothetical protein, conserved 46
L. major   LmjF.36.0360   OG5_128483   hypothetical protein, conserved 46
L. major   LmjF.07.0860   OG5_182591   hypothetical protein, unknown function 46
L. major   LmjF.15.0350   OG5_173460   hypothetical protein, conserved 46
L. major   LmjF.35.2750   OG5_184097   hypothetical protein, conserved 46
L. major   LmjF.21.1400   OG5_136877   zinc finger domain-like protein 46
L. major   LmjF.20.1420   OG5_183560   hypothetical protein, conserved 46
L. major   LmjF.19.0370   OG5_183463   hypothetical protein, conserved 46
L. major   LmjF.27.2140   OG5_170372   hypothetical protein, unknown function 46
L. major   LmjF.03.0420   OG5_183128   hypothetical protein, conserved 46
L. major   LmjF.06.0780   OG5_126579   hypothetical protein, unknown function 46
L. major   LmjF.33.1560   OG5_184033   hypothetical protein, unknown function 46
L. major   LmjF.16.0780   OG5_150049   hypothetical protein, conserved 46
L. major   LmjF.24.1270   OG5_166726   amastin-like surface protein-like protein 46
L. major   LmjF.17.1470   OG5_148215   hypothetical protein, conserved 46

Showing page 316 (records 7876-7900) of 330