Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 317 of 330 (records 7901-7925) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.04.0830   OG5_183149   hypothetical protein, conserved 46
L. major   LmjF.29.1590   OG5_183821   hypothetical protein, unknown function 46
L. major   LmjF.22.0580   OG5_127650   rer1 family-like protein 46
L. major   LmjF.14.0270   OG5_128780   hypothetical protein, conserved 46
L. major   LmjF.29.1490   OG5_128527   hypothetical protein, conserved 46
L. major   LmjF.16.0340   OG5_155655   3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 46
L. major   LmjF.02.0400     No group hypothetical protein, unknown function 46
L. major   LmjF.14.0790   OG5_183356   hypothetical protein, conserved 46
L. major   LmjF.36.1390   OG5_170280   hypothetical protein, conserved 46
L. major   LmjF.17.0450   OG5_183423   hypothetical protein, conserved 46
L. major   LmjF.34.4300   OG5_166714   hypothetical protein, conserved 46
L. major   LmjF.28.1500   OG5_128471   hypothetical protein, conserved 46
L. major   LmjF.03.0310   OG5_183127   hypothetical protein 46
L. major   LmjF.11.0540   OG5_166683   hypothetical protein, conserved 46
L. major   LmjF.27.1820   OG5_179419   hypothetical protein, unknown function 46
L. major   LmjF.04.0700   OG5_183153   hypothetical protein, conserved 46
L. major   LmjF.36.6690   OG5_126850   hypothetical protein, conserved,f2o10.10 protein-like protein 46
L. major   LmjF.03.0380   OG5_129349   hypothetical protein, conserved 46
L. major   LmjF.24.1290   OG5_130543   hypothetical protein, conserved 46
L. major   LmjF.22.0690   OG5_157933   3a2rel-related protein 46
L. major   LmjF.11.0730   OG5_183298   hypothetical protein, conserved 46
L. major   LmjF.27.0920   OG5_133214   hypothetical protein, unknown function 46
L. major   LmjF.16.1005   OG5_132978   hypothetical protein, unknown function 46
L. major   LmjF.32.0800   OG5_183955   hypothetical protein, unknown function 46
L. major   LmjF.23.1280   OG5_183624   hypothetical protein, conserved 46

Showing page 317 (records 7901-7925) of 330