Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 318 of 330 (records 7926-7950) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.19.1180   OG5_179288   hypothetical protein, conserved 46
L. major   LmjF.24.0430   OG5_183636   hypothetical protein, unknown function 46
L. major   LmjF.16.0400   OG5_183398   hypothetical protein, conserved 46
L. major   LmjF.35.0850   OG5_166769   hypothetical protein, conserved 46
L. major   LmjF.36.2740   OG5_173539   hypothetical protein, unknown function 46
L. major   LmjF.17.1140   OG5_134308   hypothetical protein, conserved 46
L. major   LmjF.06.0995   OG5_183197   hypothetical protein, unknown function 46
L. major   LmjF.26.1700   OG5_128204   fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 46
L. major   LmjF.26.1390   OG5_183714   hypothetical protein, conserved 46
L. major   LmjF.31.3030   OG5_173516   hypothetical protein, unknown function 46
L. major   LmjF.26.1850   OG5_142523   hypothetical protein, conserved 46
L. major   LmjF.23.1180   OG5_130420   hypothetical protein, conserved 46
L. major   LmjF.32.3910   OG5_134164   hypothetical protein, unknown function 46
L. major   LmjF.36.2960   OG5_166781   hypothetical protein, conserved 46
L. major   LmjF.22.0700   OG5_173478   5a2rel-related protein 46
L. major   LmjF.22.0840   OG5_173478   5a2rel-related protein 46
L. major   LmjF.29.1060   OG5_183811   hypothetical protein, conserved 46
L. major   LmjF.19.1060   OG5_183472   hypothetical protein, conserved 46
L. major   LmjF.14.0550   OG5_204196   hypothetical protein, unknown function 46
L. major   LmjF.08.0640   OG5_183239   hypothetical protein, unknown function 46
L. major   LmjF.10.0880   OG5_183280   hypothetical protein, conserved 46
L. major   LmjF.03.0280   OG5_183126   hypothetical protein 46
L. major   LmjF.06.0630   OG5_204177   hypothetical protein, unknown function 46
L. major   LmjF.31.1300   OG5_182751   hypothetical protein, conserved 46
L. major   LmjF.17.0510   OG5_173462   hypothetical protein, unknown function 46

Showing page 318 (records 7926-7950) of 330