Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 319 of 330 (records 7951-7975) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.31.0420     No group hypothetical protein, unknown function 46
L. major   LmjF.17.1310   OG5_144927   hypothetical protein, conserved 46
L. major   LmjF.16.1050   OG5_132978   hypothetical protein, conserved 46
L. major   LmjF.17.0370   OG5_181500   hypothetical protein, unknown function 46
L. major   LmjF.32.1410   OG5_183964   hypothetical protein, unknown function 46
L. major   LmjF.31.2740   OG5_127803   hypothetical protein, conserved 46
L. major   LmjF.29.0160   OG5_154351   hypothetical protein, conserved 46
L. major   LmjF.36.3240   OG5_184149   hypothetical protein, unknown function 46
L. major   LmjF.14.1250   OG5_183367   hypothetical protein, unknown function 46
L. major   LmjF.24.0980   OG5_173488   hypothetical protein, conserved 46
L. major   LmjF.34.2530   OG5_126585   hypothetical protein, unknown function 46
L. major   LmjF.09.0330   OG5_140911   hypothetical protein, conserved 46
L. major   LmjF.13.0470   OG5_166689   hypothetical protein, conserved 46
L. major   LmjF.35.0810   OG5_173079   hypothetical protein, unknown function 46
L. major   LmjF.35.1680   OG5_173531   hypothetical protein, conserved 46
L. major   LmjF.08.0760   OG5_130987   amastin-like protein 46
L. major   LmjF.34.1700   OG5_130729   amastin-like surface protein, putative 46
L. major   LmjF.02.0190   OG5_173436   phosphoglycan beta 1,3 galactosyltransferase 46
L. major   LmjF.27.1900   OG5_127609   hypothetical protein, conserved 46
L. major   LmjF.33.2080   OG5_166765   hypothetical protein, conserved 46
L. major   LmjF.35.3990   OG5_131022   hypothetical protein, conserved 46
L. major   LmjF.14.0030   OG5_161843   hypothetical protein, conserved 46
L. major   LmjF.26.2300   OG5_183726   hypothetical protein, conserved 46
L. major   LmjF.05.0840   OG5_183174   hypothetical protein, unknown function 46
L. major   LmjF.35.0010   OG5_129839   phosphoglycan beta 1,3 galactosyltransferase 7 46