Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 320 of 330 (records 7976-8000) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.32.0540   OG5_130548   hypothetical protein, conserved 46
L. major   LmjF.36.4960   OG5_184172   hypothetical protein, unknown function 46
L. major   LmjF.02.0220   OG5_204170   phosphoglycan beta 1,2 arabinosyltransferase 46
L. major   LmjF.13.1260   OG5_183335   hypothetical protein, unknown function 46
L. major   LmjF.33.2020   OG5_184042   hypothetical protein, unknown function 46
L. major   LmjF.31.1520   OG5_171791   hypothetical protein, conserved 46
L. major   LmjF.18.1285   OG5_127710   hypothetical protein, conserved 46
L. major   LmjF.31.2400   OG5_183928   hypothetical protein, unknown function 46
L. major   LmjF.08.0590   OG5_204184   hypothetical protein, unknown function 46
L. major   LmjF.08.0730   OG5_130987   amastin-like protein 46
L. major   LmjF.22.1180   OG5_182142   hypothetical protein, unknown function 46
L. major   LmjF.33.0210   OG5_184011   hypothetical protein, unknown function 46
L. major   LmjF.35.4140   OG5_184113   hypothetical protein, unknown function 46
L. major   LmjF.36.2080   OG5_184141   streptococcal hemagglutinin-like protein 46
L. major   LmjF.29.0500   OG5_183800   hypothetical protein, unknown function 46
L. major   LmjF.36.6500   OG5_166790   hypothetical protein, conserved 46
L. major   LmjF.20.1380   OG5_161858   hypothetical protein, conserved 46
L. major   LmjF.02.0520   OG5_171467   hypothetical protein, conserved 46
L. major   LmjF.22.1350   OG5_129316   hypothetical protein, conserved 46
L. major   LmjF.33.0590   OG5_130687   hypothetical protein, conserved 46
L. major   LmjF.08.0250   OG5_151460   hypothetical protein, conserved 46
L. major   LmjF.03.0260   OG5_183125   hypothetical protein, conserved 46
L. major   LmjF.36.2880   OG5_130978   hypothetical protein, conserved 46
L. major   LmjF.31.2220   OG5_163969   hypothetical protein, unknown function 46
L. major   LmjF.33.3020   OG5_184058   hypothetical protein, unknown function 46