Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 321 of 330 (records 8001-8025) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.09.0990   OG5_156093   hypothetical protein, conserved 46
L. major   LmjF.12.1005   OG5_186404   surface antigen protein 2, putative 46
L. major   LmjF.36.6620   OG5_184191   hypothetical protein, conserved 46
L. major   LmjF.33.2860   OG5_166767   hypothetical protein, conserved 46
L. major   LmjF.31.2010   OG5_183917   hypothetical protein, unknown function 46
L. major   LmjF.36.0680   OG5_184123   hypothetical protein, conserved 46
L. major   LmjF.24.1160   OG5_183649   hypothetical protein, unknown function 46
L. major   LmjF.13.1080   OG5_204195   hypothetical protein, unknown function 46
L. major   LmjF.35.1850   OG5_127900   COP-coated vesicle membrane protein gp25L precursor, putative,ER--golgi transpor ... 46
L. major   LmjF.05.0670   OG5_183170   hypothetical protein, conserved 46
L. major   LmjF.28.1390   OG5_154600   hypothetical protein, conserved 46
L. major   LmjF.12.1230   OG5_128091   hypothetical protein, conserved 46
L. major   LmjF.27.2040   OG5_129500   hypothetical protein, conserved 46
L. major   LmjF.12.1150   OG5_183323   hypothetical protein, unknown function 46
L. major   LmjF.09.0940   OG5_127300   hypothetical protein, conserved 46
L. major   LmjF.36.0960   OG5_166778   hypothetical protein, unknown function 46
L. major   LmjF.06.0330   OG5_166470   hypothetical protein, conserved 46
L. major   LmjF.23.1640   OG5_176430   hypothetical protein 46
L. major   LmjF.23.0600   OG5_183293   hypothetical protein, conserved 46
L. major   LmjF.24.1130   OG5_183648   actin-interacting protein-like protein 46
L. major   LmjF.23.1440   OG5_236273   hypothetical protein, unknown function 46
L. major   LmjF.33.0230   OG5_146998   hypothetical protein, conserved 46
L. major   LmjF.27.0780   OG5_137348   hypothetical protein, conserved 46
L. major   LmjF.11.0400   OG5_128542   tubulin-tyrsoine ligase-like protein 46
L. major   LmjF.30.0140   OG5_128025   hypothetical protein, conserved 46

Showing page 321 (records 8001-8025) of 330