Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 322 of 330 (records 8026-8050) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.23.1267   OG5_183623   hypothetical protein, unknown function 46
L. major   LmjF.32.2155   OG5_183979   hypothetical protein, conserved 46
L. major   LmjF.35.4290   OG5_182594   hypothetical protein, unknown function 46
L. major   LmjF.09.1200   OG5_183261   hypothetical protein, conserved 46
L. major   LmjF.30.1140   OG5_183849   hypothetical protein, conserved 46
L. major   LmjF.22.1620   OG5_129916   hypothetical protein, conserved 46
L. major   LmjF.23.0170   OG5_173479   hypothetical protein, conserved 46
L. major   LmjF.36.5550   OG5_184178   hypothetical protein, conserved 46
L. major   LmjF.34.3530   OG5_166712   hypothetical protein, conserved 46
L. major   LmjF.35.4450   OG5_173532   hypothetical protein, conserved 46
L. major   LmjF.35.4990   OG5_139061   phosphatidylcholine:ceramide cholinephosphotransferase 2 46
L. major   LmjF.19.1320   OG5_128109   glycerol uptake protein, putative 46
L. major   LmjF.33.1130   OG5_173526   hypothetical protein, conserved 46
L. major   LmjF.34.2230   OG5_183509   hypothetical protein, conserved 46
L. major   LmjF.35.2380   OG5_184093   hypothetical protein, unknown function 46
L. major   LmjF.22.0900   OG5_130779   hypothetical protein, conserved 46
L. major   LmjF.30.1870   OG5_173463   hypothetical protein, conserved 46
L. major   LmjF.29.2090   OG5_129072   hypothetical protein, conserved 46
L. major   LmjF.06.0810   OG5_183194   hypothetical protein, unknown function 46
L. major   LmjF.08.0690   OG5_130987   amastin-like protein 46
L. major   LmjF.23.0310   OG5_181194   hypothetical protein, conserved 46
L. major   LmjF.21.0090   OG5_166722   hypothetical protein, conserved 46
L. major   LmjF.23.1670   OG5_173083   hypothetical protein, unknown function 46
L. major   LmjF.18.1270   OG5_127710   hypothetical protein, conserved 46
L. major   LmjF.35.3070   OG5_166773   hypothetical protein, conserved 46

Showing page 322 (records 8026-8050) of 330