Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 323 of 330 (records 8051-8075) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.05.1120   OG5_204176   hypothetical protein, unknown function 46
L. major   LmjF.20.0570   OG5_183545   hypothetical protein, unknown function 46
L. major   LmjF.16.1090   OG5_183410   hypothetical protein, unknown function 46
L. major   LmjF.24.0690   OG5_183642   hypothetical predicted transmembrane protein 46
L. major   LmjF.04.0900   OG5_204134   hypothetical protein 46
L. major   LmjF.19.1360   OG5_183476   hypothetical protein, unknown function 46
L. major   LmjF.18.1265   OG5_127710   hypothetical protein, conserved 46
L. major   LmjF.08.0600   OG5_183238   hypothetical protein, unknown function 46
L. major   LmjF.07.0750   OG5_183212   hypothetical protein, conserved 46
L. major   LmjF.29.1250   OG5_183817   hypothetical protein, unknown function 46
L. major   LmjF.36.5520   OG5_127242   hypothetical protein, conserved 46
L. major   LmjF.27.2150   OG5_183749   hypothetical protein, unknown function 46
L. major   LmjF.05.1020   OG5_130035   hypothetical protein, conserved 46
L. major   LmjF.33.2580   OG5_173528   hypothetical protein, conserved 46
L. major   LmjF.32.2880   OG5_183992   hypothetical protein, unknown function 46
L. major   LmjF.12.0450   OG5_183317   hypothetical protein, unknown function 46
L. major   LmjF.27.0770   OG5_154594   hypothetical protein, conserved 46
L. major   LmjF.31.1940   OG5_173513   transcription like protein nupm1, putative 46
L. major   LmjF.15.0550   OG5_183379   hypothetical protein, unknown function 46
L. major   LmjF.28.0450   OG5_147203   ribonuclease II-like protein, putative 46
L. major   LmjF.04.0210   OG5_171326   surface antigen-like protein 46
L. major   LmjF.36.3860   OG5_184155   similar to leishmania major. l411.4-like protein 46
L. major   LmjF.26.0710   OG5_141538   sphingosine kinase A, B, putative 46
L. major   LmjF.32.1160   OG5_126732   long chain polyunsaturated fatty acid elongation enzyme-like protein 46
L. major   LmjF.04.0230   OG5_183162   hypothetical protein, conserved 46

Showing page 323 (records 8051-8075) of 330