Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 324 of 330 (records 8076-8100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.34.0220   OG5_183483   hypothetical protein, unknown function 46
L. major   LmjF.34.1920   OG5_130729   amastin-like surface protein, putative 46
L. major   LmjF.24.1280   OG5_157940   amastin-like surface protein-like protein 46
L. major   LmjF.28.1400   OG5_183776   amastin-like protein 46
L. major   LmjF.08.0830   OG5_130987   amastin-like protein 46
L. major   LmjF.06.0620   OG5_128461   hypothetical protein, conserved 46
L. major   LmjF.35.2520   OG5_132180   hypothetical protein, conserved 46
L. major   LmjF.15.0815   OG5_130672   hypothetical protein, conserved 46
L. major   LmjF.31.2570   OG5_183934   hypothetical protein, unknown function 46
L. major   LmjF.13.0840   OG5_182716   hypothetical protein, unknown function 46
L. major   LmjF.33.3080   OG5_184061   hypothetical protein, unknown function 46
L. major   LmjF.33.0880   OG5_184020   hypothetical protein, conserved 46
L. major   LmjF.31.2110   OG5_172461   hypothetical protein, unknown function 46
L. major   LmjF.03.0460   OG5_156080   hypothetical protein 46
L. major   LmjF.31.1390   OG5_183902   hypothetical protein, unknown function 46
L. major   LmjF.08.0750   OG5_130987   amastin-like protein 46
L. major   LmjF.05.0940   OG5_183177   hypothetical protein, conserved 46
L. major   LmjF.05.0680   OG5_127740   sre-2/carboxylate carrier-like protein 46
L. major   LmjF.08.0700   OG5_130987   amastin-like protein 46
L. major   LmjF.18.0570   OG5_132778   hypothetical protein, conserved 46
L. major   LmjF.18.1180   OG5_183451   hypothetical protein, conserved 46
L. major   LmjF.08.0810   OG5_130987   amastin-like protein 46
L. major   LmjF.23.0580   OG5_157918   hypothetical protein, conserved 46
L. major   LmjF.14.0490   OG5_157921   hypothetical protein, unknown function 46
L. major   LmjF.26.0185   OG5_161883   hypothetical protein, conserved 46

Showing page 324 (records 8076-8100) of 330