Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 327 of 330 (records 8151-8175) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.15.1190   OG5_166695   hypothetical protein, conserved 46
L. major   LmjF.31.1310   OG5_166756   hypothetical protein, conserved 46
L. major   LmjF.06.0720   OG5_178201   hypothetical protein, conserved 46
L. major   LmjF.32.1520   OG5_183966   hypothetical protein, conserved 46
L. major   LmjF.10.0660   OG5_183278   hypothetical protein, unknown function 46
L. major   LmjF.04.0790   OG5_183148   hypothetical protein, conserved 46
L. major   LmjF.32.1040   OG5_183958   hypothetical protein, conserved 46
L. major   LmjF.03.0820   OG5_183133   hypothetical protein, conserved 46
L. major   LmjF.33.2330   OG5_184047   hypothetical protein, unknown function 46
L. major   LmjF.32.0290   OG5_183950   hypothetical protein, conserved 46
L. major   LmjF.28.0990   OG5_127560   hypothetical protein, conserved 46
L. major   LmjF.30.1170   OG5_175507   hypothetical protein, unknown function 46
L. major   LmjF.31.1330   OG5_183888   hypothetical protein, unknown function 46
L. major   LmjF.25.0900   OG5_183672   hypothetical protein, unknown function 46
L. major   LmjF.31.2670   OG5_163884   hypothetical protein, unknown function 46
L. major   LmjF.32.3730   OG5_131151   hypothetical protein, conserved 46
L. major   LmjF.36.5210   OG5_149113   hypothetical protein, conserved 46
L. major   LmjF.26.1260   OG5_183711   hypothetical protein, unknown function 46
L. major   LmjF.26.1460   OG5_183716   hypothetical protein, unknown function 46
L. major   LmjF.19.1347   OG5_128109   hypothetical protein, conserved 46
L. major   LmjF.35.3400   OG5_127172   hypothetical protein, conserved 46
L. major   LmjF.19.1000   OG5_128109   glycerol uptake protein, putative 46
L. major   LmjF.23.1070   OG5_153296   hydrophilic acylated surface protein b 41
L. major   LmjF.36.1550   OG5_144346   hypothetical protein, conserved 41
L. major   LmjF.06.0300   OG5_178819   MYND finger domain-like protein 41

Showing page 327 (records 8151-8175) of 330