Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 328 of 330 (records 8176-8200) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.23.1120   OG5_184200   hypothetical protein, unknown function 41
L. major   LmjF.36.6360   OG5_152076   hypothetical protein, conserved 41
L. major   LmjF.23.1060   OG5_153296   hydrophilic acylated surface protein b 41
L. major   LmjF.25.0350   OG5_154532   hypothetical protein, conserved 41
L. major   LmjF.34.4270   OG5_130249   hypothetical protein, conserved 41
L. major   LmjF.28.3010   OG5_132347   hypothetical protein, conserved 41
L. major   LmjF.21.1530   OG5_130178   hypothetical protein, conserved 41
L. major   LmjF.27.1770   OG5_168030   hypothetical protein, conserved 31
L. major   LmjF.20.0150   OG5_132070   hypothetical protein 31
L. major   LmjF.22.1700   OG5_136355   hypothetical protein 31
L. major   LmjF.15.0600   OG5_183382   hypothetical protein, conserved 26
L. major   LmjF.29.2190   OG5_183830   hypothetical protein, conserved 26
L. major   LmjF.24.0440   OG5_145978   hypothetical predicted transmembrane protein 26
L. major   LmjF.04.0600   OG5_204174   hypothetical protein 26
L. major   LmjF.15.0630   OG5_183384   hypothetical protein, unknown function 26
L. major   LmjF.03.0550   OG5_183129   hypothetical protein, conserved 26
L. major   LmjF.35.4540   OG5_140502   hypothetical protein, conserved 26
L. major   LmjF.17.1230   OG5_144292   hypothetical protein, conserved 26
L. major   LmjF.22.1100   OG5_183599   hypothetical protein, conserved 26
L. major   LmjF.28.0080   OG5_183755   hypothetical protein, unknown function 26
L. major   LmjF.13.0740   OG5_128478   hypothetical protein, unknown function 26
L. major   LmjF.12.0340   OG5_183315   hypothetical protein, unknown function 26
L. major   LmjF.27.0020   OG5_130424   hypothetical protein, conserved 26
L. major   LmjF.25.0790   OG5_183669   hypothetical protein, unknown function 26
L. major   LmjF.04.0510   OG5_183143   hypothetical protein 26

Showing page 328 (records 8176-8200) of 330