Target list

Search results for query: PLoS NTD Query 3 (L. major, w/ essentiality)

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  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #103 (Mtb any essentiality evidence (now searched on lma)): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 326 of 330 (records 8126-8150) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.34.1390   OG5_152421   hypothetical protein, conserved 46
L. major   LmjF.14.1090   OG5_128566   hypothetical protein, conserved 46
L. major   LmjF.06.0760   OG5_183192   hypothetical protein, conserved 46
L. major   LmjF.30.0550   OG5_128525   hypothetical protein, conserved 46
L. major   LmjF.16.0710   OG5_183403   hypothetical protein, conserved 46
L. major   LmjF.32.3240   OG5_183995   hypothetical protein, conserved 46
L. major   LmjF.16.1015   OG5_132978   hypothetical protein, conserved 46
L. major   LmjF.13.1410   OG5_164172   hypothetical protein, unknown function 46
L. major   LmjF.08.0850   OG5_130987   amastin-like protein 46
L. major   LmjF.04.0870   OG5_183150   hypothetical protein 46
L. major   LmjF.19.1050   OG5_183471   hypothetical protein, unknown function 46
L. major   LmjF.25.0100   OG5_166730   hypothetical protein, conserved 46
L. major   LmjF.34.0660   OG5_183494   hypothetical protein, unknown function 46
L. major   LmjF.08.0630   OG5_166008   hypothetical protein, unknown function 46
L. major   LmjF.20.0630   OG5_183546   hypothetical protein, conserved 46
L. major   LmjF.22.0640   OG5_183595   hypothetical protein, conserved 46
L. major   LmjF.31.2620   OG5_131648   hypothetical protein, conserved 46
L. major   LmjF.30.0850   OG5_157974   surface protein amastin, putative 46
L. major   LmjF.26.1680   OG5_128204   fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 46
L. major   LmjF.24.1190   OG5_129362   hypothetical protein, conserved 46
L. major   LmjF.01.0010   OG5_183100   hypothetical protein, unknown function 46
L. major   LmjF.12.1210   OG5_183325   hypothetical protein, unknown function 46
L. major   LmjF.23.1430   OG5_159800   DHHC zinc finger domain-like protein 46
L. major   LmjF.13.1310   OG5_183337   hypothetical protein, unknown function 46
L. major   LmjF.14.0370   OG5_182040   hypothetical protein, conserved 46

Showing page 326 (records 8126-8150) of 330