Target list

Search results for query: PLoS NTD query (L. major)

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  • Score for genes in query #534 (L. major assayability precedent): 35
  • Score for genes in query #526 (L. major no transmembrane domains): 20
  • Score for genes in query #523 (L. major enzymes): 100
  • Score for genes in query #524 (L. major PubMed publications): 35
  • Score for genes in query #531 (L. major genetic validation): 50
  • Score for genes in query #525 (L. major MW < 100 kD): 20
  • Score for genes in query #530 (L. major conserved in TriTryps): 25
  • Score for genes in query #528 (L. major ModBase models): 30
  • Score for genes in query #522 (all L. major proteins): 1
  • Score for genes in query #529 (L. major not in humans): 25
  • Score for genes in query #527 (L. major PDB structures): 50
  • Score for genes in query #532 (L. major druggability >=0.6): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8243 records found | Showing page 3 of 330 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.19.0550   OG5_126721   methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 301
L. major   LmjF.32.1580   OG5_127555   phosphomannose isomerase 301
L. major   LmjF.30.0880   OG5_128398   adenosine kinase, putative 301
L. major   LmjF.21.0250   OG5_126743   hexokinase, putative 301
L. major   LmjF.26.2530   OG5_127131   serine/threonine protein phosphatase, putative 301
L. major   LmjF.25.1320   OG5_127141   serine/threonine protein phosphatase, putative 301
L. major   LmjF.34.0110   OG5_126762   adenylate kinase, putative 301
L. major   LmjF.13.1190   OG5_127011   adenylosuccinate synthetase, putative 301
L. major   LmjF.08.1040   OG5_126607   cathepsin L-like protease 296
L. major   LmjF.19.1420   OG5_126607   cysteine peptidase A (CPA) 296
L. major   LmjF.36.3130   OG5_140933   cyclophilin 10, putative 291
L. major   LmjF.36.5380   OG5_126960   NADH dehydrogenase, putative 291
L. major   LmjF.13.0420   OG5_142658   long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty a ... 291
L. major   LmjF.34.0810   OG5_129030   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.32.1020   OG5_154653   protein kinase, putative 291
L. major   LmjF.16.1200   OG5_148443   cyclophilin 13, putative 291
L. major   LmjF.08.0510   OG5_147625   ribose-phosphate pyrophosphokinase, putative 291
L. major   LmjF.30.0380   OG5_136796   phosphatase 2C, putative 291
L. major   LmjF.25.0750   OG5_150267   protein phosphatase, putative 291
L. major   LmjF.16.0550   OG5_126793   orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative, ... 291
L. major   LmjF.15.0170   OG5_142545   protein phosphatase 2C, putative 291
L. major   LmjF.28.1970   OG5_129695   ribose 5-phosphate isomerase, putative 291
L. major   LmjF.04.0450   OG5_135138   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2 ... 291
L. major   LmjF.22.1450   OG5_141132   cyclophilin 6, putative 291
L. major   LmjF.03.0910   OG5_128875   inorganic pyrophosphatase, putative 291

Showing page 3 (records 51-75) of 330