Target list

Search results for query: PLoS NTD query (L. major)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #522 (all L. major proteins): 1
  • Score for genes in query #532 (L. major druggability >=0.6): 35
  • Score for genes in query #528 (L. major ModBase models): 30
  • Score for genes in query #527 (L. major PDB structures): 50
  • Score for genes in query #523 (L. major enzymes): 100
  • Score for genes in query #524 (L. major PubMed publications): 35
  • Score for genes in query #531 (L. major genetic validation): 50
  • Score for genes in query #530 (L. major conserved in TriTryps): 25
  • Score for genes in query #534 (L. major assayability precedent): 35
  • Score for genes in query #525 (L. major MW < 100 kD): 20
  • Score for genes in query #526 (L. major no transmembrane domains): 20
  • Score for genes in query #529 (L. major not in humans): 25

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 4 of 330 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.29.2670   OG5_150111   serine/threonine-protein kinase Nek3, putative,protein kinase, putative 291
L. major   LmjF.28.3000   OG5_148164   protein kinase, putative 291
L. major   LmjF.36.2390   OG5_129172   sterol 24-c-methyltransferase, putative 291
L. major   LmjF.30.2770   OG5_148158   superoxide dismutase, putative 291
L. major   LmjF.29.2490   OG5_154473   protein kinase, putative 291
L. major   LmjF.31.3160   OG5_139463   protein kinase, putative 291
L. major   LmjF.34.0130   OG5_150839   malate dehydrogenase, putative 291
L. major   LmjF.31.0840   OG5_127315   lipase precursor-like protein 291
L. major   LmjF.01.0220   OG5_133785   cyclophilin 12, putative 291
L. major   LmjF.02.0360   OG5_143898   casein kinase II, alpha chain, putative 291
L. major   LmjF.01.0500   OG5_126601   fatty acyl CoA synthetase 2, putative 291
L. major   LmjF.08.0100   OG5_141243   dual-specificity protein phosphatase, putative 291
L. major   LmjF.36.1360   OG5_138748   adenylate kinase, putative 291
L. major   LmjF.35.3010   OG5_127627   glyoxalase I,trypanothione-dependent glyoxalase I 291
L. major   LmjF.31.2960   OG5_142254   serine/threonine-protein kinase, putative,protein kinase, putative 291
L. major   LmjF.08.1130   OG5_150487   phosphoribosylpyrophosphate synthetase 291
L. major   LmjF.09.0470   OG5_138572   serine/threonine protein phosphatase, putative 291
L. major   LmjF.32.2630   OG5_153133   superoxide dismutase, putative 291
L. major   LmjF.25.2340   OG5_129514   serine/threonine-protein kinase, putative,protein kinase, putative 291
L. major   LmjF.18.1060   OG5_148485   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2 ... 291
L. major   LmjF.29.2570   OG5_144700   serine/threonine-protein kinase, putative,protein kinase, putative 291
L. major   LmjF.20.1185   OG5_135138   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2 ... 291
L. major   LmjF.05.0100   OG5_138502   phosphoprotein phosphatase, putative 291
L. major   LmjF.29.1330   OG5_153007   serine/threonine-protein kinase, putative,protein kinase, putative 291
L. major   LmjF.36.2380   OG5_129172   sterol 24-c-methyltransferase, putative 291

Showing page 4 (records 76-100) of 330