Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0597c | OG5_157133 | Conserved hypothetical protein | 234 |
M. tuberculosis | Rv3111 | OG5_129779 | Probable molybdenum cofactor biosynthesis protein C MoaC1 | 214 |
M. tuberculosis | Rv2257c | OG5_229489 | Conserved protein | 205 |
M. tuberculosis | Rv1627c | OG5_146299 | Probable nonspecific lipid-transfer protein | 201 |
M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... | 194 |
M. tuberculosis | Rv0969 | OG5_126855 | Probable metal cation transporter P-type ATPase CtpV | 193 |
M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) | 188 |
M. tuberculosis | Rv3775 | OG5_139404 | Probable lipase LipE | 187 |
M. tuberculosis | Rv3819 | No group | Unknown protein | 187 |
M. tuberculosis | Rv1259 | OG5_149670 | Probable uracil DNA glycosylase, UdgB | 175 |
M. tuberculosis | Rv2632c | OG5_239144 | Conserved protein | 175 |
M. tuberculosis | Rv3377c | OG5_163665 | Halimadienyl diphosphate synthase | 173 |
M. tuberculosis | Rv2591 | OG5_129879 | PE-PGRS family protein PE_PGRS44 | 170 |
M. tuberculosis | Rv0295c | No group | Conserved protein | 170 |
M. tuberculosis | Rv0792c | OG5_134860 | Probable transcriptional regulatory protein (probably GntR-family) | 170 |
M. tuberculosis | Rv2353c | OG5_132376 | PPE family protein PPE39 | 168 |
M. tuberculosis | Rv2468c | OG5_237676 | Conserved protein | 168 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 167 |
M. tuberculosis | Rv2237 | OG5_163412 | Conserved protein | 167 |
M. tuberculosis | Rv2875 | OG5_133411 | Major secreted immunogenic protein Mpt70 | 166 |
M. tuberculosis | Rv0623 | OG5_204775 | Possible antitoxin VapB30 | 165 |
M. tuberculosis | Rv1613 | OG5_130207 | Probable tryptophan synthase, alpha subunit TrpA | 165 |
M. tuberculosis | Rv1464 | OG5_128800 | Probable cysteine desulfurase Csd | 164 |
M. tuberculosis | Rv0752c | OG5_136059 | Probable acyl-CoA dehydrogenase FadE9 | 164 |
M. tuberculosis | Rv2079 | OG5_161998 | Conserved hypothetical protein | 162 |