Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 3 of 91 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0948c | OG5_237559 | Chorismate mutase | 141 |
M. tuberculosis | Rv1689 | OG5_127413 | Probable tyrosyl-tRNA synthase TyrS (TYRRS) | 141 |
M. tuberculosis | Rv3068c | OG5_127226 | Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM) | 140 |
M. tuberculosis | Rv3116 | OG5_126966 | Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylas ... | 138 |
M. tuberculosis | Rv0585c | OG5_187211 | Probable conserved integral membrane protein | 137 |
M. tuberculosis | Rv1287 | OG5_132733 | Conserved hypothetical protein | 137 |
M. tuberculosis | Rv2699c | OG5_237649 | Conserved hypothetical protein | 137 |
M. tuberculosis | Rv1737c | OG5_158923 | Possible nitrate/nitrite transporter NarK2 | 136 |
M. tuberculosis | Rv2104c | OG5_239154 | Possible antitoxin VapB37 | 136 |
M. tuberculosis | Rv2362c | OG5_143159 | Possible DNA repair protein RecO | 135 |
M. tuberculosis | Rv1526c | OG5_128871 | Probable glycosyltransferase | 135 |
M. tuberculosis | Rv2526 | No group | Possible antitoxin VapB17 | 135 |
M. tuberculosis | Rv1580c | No group | Probable PhiRv1 phage protein | 134 |
M. tuberculosis | Rv2874 | OG5_208929 | Possible integral membrane C-type cytochrome biogenesis protein DipZ | 132 |
M. tuberculosis | Rv1122 | OG5_127175 | Probable 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 | 132 |
M. tuberculosis | Rv0705 | OG5_126687 | 30S ribosomal protein S19 RpsS | 129 |
M. tuberculosis | Rv1056 | OG5_144561 | Conserved protein | 129 |
M. tuberculosis | Rv2908c | OG5_140153 | Conserved hypothetical protein | 129 |
M. tuberculosis | Rv3677c | OG5_129461 | Possible hydrolase | 129 |
M. tuberculosis | Rv3469c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) | 128 |
M. tuberculosis | Rv1780 | OG5_237692 | Conserved protein | 128 |
M. tuberculosis | Rv0415 | OG5_144261 | Possible thiamine biosynthesis oxidoreductase ThiO | 128 |
M. tuberculosis | Rv1403c | OG5_176030 | Putative methyltransferase | 127 |
M. tuberculosis | Rv1556 | OG5_191207 | Possible regulatory protein | 127 |
M. tuberculosis | Rv0140 | OG5_144561 | Conserved protein | 125 |