Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.2066 | 1 | 1 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.2066 | 1 | 1 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.2066 | 1 | 0.5 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.2066 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0569 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.1243 | 0.5928 | 0.5928 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.1243 | 0.5928 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1243 | 0.5928 | 0.5928 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.2066 | 1 | 1 |
Onchocerca volvulus | 0.1243 | 0.5928 | 1 | |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.2066 | 1 | 1 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1243 | 0.5928 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2066 | 1 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.0569 | 0.0959 |
Plasmodium vivax | polyprenol reductase, putative | 0.1243 | 0.5928 | 0.5 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.1243 | 0.5928 | 0.5928 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.2066 | 1 | 1 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.1243 | 0.5928 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.0569 | 0.0569 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.2066 | 1 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.0569 | 0.0569 |
Plasmodium falciparum | polyprenol reductase, putative | 0.1243 | 0.5928 | 0.5 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.1243 | 0.5928 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0569 | 0.0959 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.2066 | 1 | 1 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.1243 | 0.5928 | 1 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.1243 | 0.5928 | 1 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.1243 | 0.5928 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.2066 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0458 | 0.0773 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1243 | 0.5928 | 0.5 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.1243 | 0.5928 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0458 | 0.0773 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.