TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 508.494 | Formula: C25H30F6O4
H donors: 0 H acceptors: 0 LogP: 7.12 Rotable bonds: 6
Rule of 5 violations (Lipinski): 2
SMILES: C[C@@H]1CC[C@@H]2[C@@]34[C@H]1CC[C@](OO3)(O[C@H]4OC[C@@H]2CCCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C
InChi: 1S/C25H30F6O4/c1-14-6-7-20-16(13-32-21-23(20)19(14)8-9-22(2,33-21)34-35-23)5-3-4-15-10-17(24(26,27)28)12-18(11-15)25(29,30)31/h10-12,14,16,19-21H,3-9,13H2,1-2H3/t14-,16+,19+,20+,21-,22+,23-/m1/s1
InChiKey: FUTOREOLEFXZAH-RZUHFWIZSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	cyclin dependent kinase 5	0.00970412	0.0414115	0.0717227
Loa Loa (eye worm)	hypothetical protein	0.0064172	0.0188926	0.0229669
Brugia malayi	serine/threonine kinase 12	0.0238661	0.138436	0.24091
Brugia malayi	hypothetical protein	0.00495918	0.0089036	0.015037
Echinococcus multilocularis	roundabout 2	0.0117326	0.0553086	0.0959557
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0238661	0.138436	0.704003
Giardia lamblia	Kinase, CMGC CDK	0.00970412	0.0414115	0.209593
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.00429599	0.00436011	0.00711433
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0238661	0.138436	0.704003
Schistosoma mansoni	nephrin	0.00971561	0.0414902	0.07186
Echinococcus multilocularis		0.0258901	0.152303	0.265089
Mycobacterium ulcerans	mycothiol conjugate amidase Mca	0.149622	1	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.00429599	0.00436011	0.00503443
Brugia malayi	hypothetical protein	0.00429599	0.00436011	0.00711433
Trichomonas vaginalis	CMGC family protein kinase	0.00970412	0.0414115	0.209593
Brugia malayi	Furin-like cysteine rich region family protein	0.0874067	0.573757	1
Loa Loa (eye worm)	AUR protein kinase	0.0238661	0.138436	0.170479
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0762478	0.497306	0.866689
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.00419369	0.0036592	0.00589211
Entamoeba histolytica	PH domain containing protein kinase, putative	0.00544002	0.0121979	0.0607289
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0117375	0.055342	0.096014
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.00698006	0.0227488	0.0391796
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0874067	0.573757	0.707646
Giardia lamblia	Kinase, AGC PKA	0.00516456	0.0103107	0.0511125
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Echinococcus granulosus	5'partial\|cyclin dependent kinase 1	0.00970412	0.0414115	0.0717227
Schistosoma mansoni	vesicular amine transporter	0.00698006	0.0227488	0.0391796
Echinococcus multilocularis	Glutaredoxin protein 5	0.00419369	0.0036592	0.00589211
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0117375	0.055342	0.096014
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0117375	0.055342	0.096014
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.00899702	0.0365671	0.0632753
Echinococcus granulosus	epidermal growth factor receptor	0.0591692	0.3803	0.66266
Schistosoma mansoni	protein kinase	0.0238661	0.138436	0.24091
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00475252	0.00748779	0.0125682
Onchocerca volvulus		0.00370643	0.000320959	0.0000926542
Trypanosoma cruzi	cdc2-related kinase 1	0.00970412	0.0414115	0.209593
Trypanosoma brucei	cdc2-related kinase 3	0.00970412	0.0414115	0.209593
Echinococcus multilocularis	aurora kinase A	0.0238661	0.138436	0.24091
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0102617	0.0452313	0.0783834
Echinococcus granulosus	Immunoglobulin	0.00698006	0.0227488	0.0391796
Brugia malayi	Protein kinase domain containing protein	0.00429599	0.00436011	0.00711433
Echinococcus granulosus	contactin	0.00475252	0.00748779	0.0125682
Brugia malayi	SRC-1	0.0117375	0.055342	0.096014
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0238661	0.138436	0.24091
Entamoeba histolytica	PH domain containing protein kinase, putative	0.00544002	0.0121979	0.0607289
Schistosoma mansoni	ephrin receptor	0.0139476	0.0704838	0.122418
Leishmania major	cell division protein kinase 2,cdc2-related kinase	0.00970412	0.0414115	0.209593
Schistosoma mansoni	serine/threonine protein kinase	0.00970412	0.0414115	0.0717227
Giardia lamblia	Glucosamine-6-phosphate isomerase, putative	0.0064607	0.0191906	0.0963619
Loa Loa (eye worm)	TK/FAK protein kinase	0.0610186	0.39297	0.484563
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0102617	0.0452313	0.0783834
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Plasmodium vivax	unspecified product	0.0279297	0.166276	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.00747902	0.0261672	0.0451405
Echinococcus granulosus	tyrosine protein kinase HCK	0.00874831	0.0348632	0.0603041
Schistosoma mansoni	tyrosine kinase	0.00429599	0.00436011	0.00711433
Brugia malayi	Protein kinase domain containing protein	0.00757922	0.0268537	0.0463375
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00475252	0.00748779	0.0125682
Brugia malayi	Trypsin family protein	0.00495918	0.0089036	0.015037
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0117375	0.055342	0.096014
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.00475252	0.00748779	0.0125682
Brugia malayi	Trypsin family protein	0.00495918	0.0089036	0.015037
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Loa Loa (eye worm)	plexin A	0.00406685	0.00279021	0.00309723
Brugia malayi	Casein kinase II, alpha chain	0.0279297	0.166276	0.289455
Trypanosoma cruzi	cdc2-related kinase 1	0.00970412	0.0414115	0.209593
Mycobacterium tuberculosis	Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase)	0.143162	0.955737	1
Plasmodium falciparum	protein kinase 5	0.00970412	0.0414115	0.247785
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.00419369	0.0036592	0.00589211
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0162045	0.085946	0.105708
Trichomonas vaginalis	CMGC family protein kinase	0.00970412	0.0414115	0.209593
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00813561	0.0306655	0.0529844
Echinococcus granulosus	calcium:calmodulin dependent protein kinase	0.00516456	0.0103107	0.0174907
Mycobacterium ulcerans	N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB	0.0064607	0.0191906	0.0103794
Echinococcus granulosus	proto oncogene serine:threonine protein kinase	0.0162045	0.085946	0.14938
Toxoplasma gondii	aurora kinase	0.0238661	0.138436	0.83192
Echinococcus granulosus	Serine:threonine protein kinase PLK4	0.0310993	0.187991	0.327321
Entamoeba histolytica	protein kinase domain containing protein	0.0279297	0.166276	0.845865
Echinococcus granulosus	glycoprotein Antigen 5	0.00495918	0.0089036	0.015037
Echinococcus granulosus	enteropeptidase	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	trypsin family protein	0.00495918	0.0089036	0.0106409
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0238661	0.138436	0.24091
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Entamoeba histolytica	protein kinase, putative	0.00874831	0.0348632	0.176225
Brugia malayi	Immunoglobulin I-set domain containing protein	0.075314	0.490909	0.855534
Echinococcus granulosus	tyrosine protein kinase Blk	0.0102617	0.0452313	0.0783834
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0762478	0.497306	0.866689
Loa Loa (eye worm)	hypothetical protein	0.00873325	0.03476	0.0425466
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.00436264	0.00481672	0.00791055
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Trypanosoma brucei	aurora B kinase	0.0238661	0.138436	0.704003
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Schistosoma mansoni	titin	0.00370643	0.000320959	0.000071059
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Brugia malayi	protein-tyrosine kinase	0.0102617	0.0452313	0.0783834
Onchocerca volvulus		0.0635344	0.410206	0.932042
Schistosoma mansoni	tyrosine kinase	0.0750922	0.489389	0.852884
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Echinococcus multilocularis	cyclin dependent kinase 1	0.00970412	0.0414115	0.0717227
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Giardia lamblia	Kinase, CMGC CDK	0.00970412	0.0414115	0.209593
Trypanosoma cruzi	casein kinase II, putative	0.0279297	0.166276	0.845865
Echinococcus multilocularis	cyclin dependent kinase	0.00970412	0.0414115	0.0717227
Echinococcus granulosus	plexin a4	0.00406685	0.00279021	0.00437681
Trypanosoma brucei	protein kinase, putative	0.00375351	0.000643539	0.00185143
Schistosoma mansoni	tyrosine kinase	0.0591692	0.3803	0.66266
Echinococcus multilocularis	Immunoglobulin	0.00698006	0.0227488	0.0391796
Onchocerca volvulus		0.011165	0.0514198	0.116275
Echinococcus multilocularis	cyclin dependent kinase 1	0.00970412	0.0414115	0.0717227
Echinococcus multilocularis	N acetylglucosaminyl phosphatidylinositol	0.0064607	0.0191906	0.032975
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0238661	0.138436	0.832288
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.075314	0.490909	0.605416
Brugia malayi	serine/threonine-protein kinase plk-2	0.0323448	0.196524	0.3422
Giardia lamblia	Kinase, PLK	0.0323448	0.196524	1
Schistosoma mansoni	tyrosine kinase	0.0563866	0.361236	0.629417
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.00375351	0.000643539	0.00185143
Loa Loa (eye worm)	CAMK protein kinase	0.00370643	0.000320959	0.0000502846
Loa Loa (eye worm)	hypothetical protein	0.011165	0.0514198	0.0631041
Echinococcus multilocularis	glycoprotein Antigen 5	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Entamoeba histolytica	protein kinase 2, putative	0.00516456	0.0103107	0.0511125
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Echinococcus multilocularis	Immunoglobulin	0.00698006	0.0227488	0.0391796
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Schistosoma mansoni	tyrosine kinase	0.0874067	0.573757	1
Schistosoma mansoni	tyrosine kinase	0.0563866	0.361236	0.629417
Echinococcus granulosus	cyclin dependent kinase 1	0.00970412	0.0414115	0.0717227
Mycobacterium leprae	Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)	0.149622	1	1
Entamoeba histolytica	protein kinase, putative	0.00730377	0.0249665	0.125794
Echinococcus granulosus	c src tyrosine kinase	0.00577178	0.0144708	0.0247449
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Echinococcus multilocularis	activin receptor type	0.00375351	0.000643539	0.000633558
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.00429599	0.00436011	0.00711433
Leishmania major	protein kinase, putative	0.0238661	0.138436	0.704003
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.00475252	0.00748779	0.0125682
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Schistosoma mansoni	protein kinase	0.00375351	0.000643539	0.000633558
Schistosoma mansoni	serine/threonine protein kinase	0.0162045	0.085946	0.14938
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Loa Loa (eye worm)	AUR protein kinase	0.0238661	0.138436	0.170479
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Echinococcus granulosus	serine threonine protein kinase nrc	0.00516456	0.0103107	0.0174907
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.00475252	0.00748779	0.00889385
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.00495918	0.0089036	0.015037
Entamoeba histolytica	glucosamine-6-phosphate isomerase, putative	0.0064607	0.0191906	0.0963619
Plasmodium falciparum	casein kinase 2, alpha subunit	0.0279297	0.166276	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0127083	0.0619935	0.107613
Toxoplasma gondii	AGC kinase	0.00730377	0.0249665	0.146849
Schistosoma mansoni	nephrin	0.00475252	0.00748779	0.0125682
Echinococcus multilocularis	cyclin dependent kinase 5	0.00970412	0.0414115	0.0717227
Echinococcus granulosus	N acetylglucosaminyl phosphatidylinositol	0.0064607	0.0191906	0.032975
Echinococcus granulosus	Mastin	0.00495918	0.0089036	0.015037
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.00577178	0.0144708	0.0247449
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.00698006	0.0227488	0.0391796
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0323448	0.196524	0.446197
Trypanosoma cruzi	cdc2-related kinase 3	0.00970412	0.0414115	0.209593
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.00747902	0.0261672	0.0451405
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.00572339	0.0141393	0.0171016
Schistosoma mansoni	tyrosine kinase	0.00577178	0.0144708	0.0247449
Entamoeba histolytica	cell division protein kinase 2, putative	0.00970412	0.0414115	0.209593
Schistosoma mansoni	tyrosine kinase	0.0591692	0.3803	0.66266
Entamoeba histolytica	cell division protein kinase 2, putative	0.00970412	0.0414115	0.209593
Trichomonas vaginalis	CAMK family protein kinase	0.0109083	0.0496615	0.251632
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.00429599	0.00436011	0.02079
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0102617	0.0452313	0.0783834
Brugia malayi	serine/threonine-protein kinase 6	0.0238661	0.138436	0.24091
Trypanosoma cruzi	polo-like protein kinase, putative	0.0323448	0.196524	1
Brugia malayi	serine/threonine protein kinase 6	0.0238661	0.138436	0.24091
Schistosoma mansoni	serine/threonine protein kinase	0.00425843	0.00410275	0.00666555
Echinococcus granulosus	aurora kinase A	0.0238661	0.138436	0.24091
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Schistosoma mansoni	serine/threonine protein kinase	0.00370643	0.000320959	0.000071059
Echinococcus granulosus	tyrosine protein kinase Srms	0.00429599	0.00436011	0.00711433
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.00475252	0.00748779	0.0125682
Schistosoma mansoni	ephrin receptor	0.00393819	0.00190878	0.00283983
Trypanosoma brucei	rac serine-threonine kinase, putative	0.00757922	0.0268537	0.135411
Toxoplasma gondii	cell-cycle-associated protein kinase CDK, putative	0.00970412	0.0414115	0.246135
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0323448	0.196524	0.3422
Loa Loa (eye worm)	TK protein kinase	0.00436264	0.00481672	0.00559787
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Schistosoma mansoni	tyrosine kinase	0.0117375	0.055342	0.096014
Plasmodium falciparum	RAC-beta serine/threonine protein kinase	0.00516456	0.0103107	0.0604263
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00475252	0.00748779	0.0125682
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.00970412	0.0414115	0.0507543
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.00495918	0.0089036	0.015037
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0323448	0.196524	1
Echinococcus multilocularis	enteropeptidase	0.00495918	0.0089036	0.015037
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Trichomonas vaginalis	AGC family protein kinase	0.0238661	0.138436	0.704003
Schistosoma mansoni	tyrosine kinase	0.00637961	0.0186351	0.0320063
Schistosoma mansoni	hypothetical protein	0.00495918	0.0089036	0.015037
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Schistosoma mansoni	tyrosine kinase	0.0750922	0.489389	0.852884
Brugia malayi	Trypsin family protein	0.00495918	0.0089036	0.015037
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Schistosoma mansoni	cell adhesion molecule	0.0101526	0.0444839	0.0770802
Trichomonas vaginalis	AGC family protein kinase	0.0238661	0.138436	0.704003
Echinococcus granulosus	roundabout 2	0.00475252	0.00748779	0.0125682
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.00495918	0.0089036	0.015037
Echinococcus granulosus	defective proboscis extension response	0.00698006	0.0227488	0.0391796
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Entamoeba histolytica	protein kinase domain containing protein	0.0238661	0.138436	0.704003
Echinococcus multilocularis	c src tyrosine kinase	0.00577178	0.0144708	0.0247449
Schistosoma mansoni	cell adhesion molecule	0.00475252	0.00748779	0.0125682
Echinococcus multilocularis	tyrosine protein kinase shark	0.00429599	0.00436011	0.00711433
Trypanosoma cruzi	N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative	0.0064607	0.0191906	0.0963619
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0323448	0.196524	0.3422
Schistosoma mansoni	tyrosine kinase	0.00577178	0.0144708	0.0247449
Brugia malayi	Tyrosine-protein kinase abl-1	0.00577178	0.0144708	0.0247449
Plasmodium vivax	N-acetylglucosaminylphosphatidylinositol deacetylase, putative	0.0064607	0.0191906	0.115414
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0102617	0.0452313	0.0783834
Echinococcus granulosus	tyrosine kinase	0.00429599	0.00436011	0.00711433
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Schistosoma mansoni	cell adhesion molecule	0.00475252	0.00748779	0.0125682
Brugia malayi	Uncharacterized LmbE-like protein, COG2120 containing protein	0.0064607	0.0191906	0.032975
Echinococcus multilocularis	roundabout 2	0.00475252	0.00748779	0.0125682
Echinococcus multilocularis	tyrosine kinase	0.00429599	0.00436011	0.00711433
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Schistosoma mansoni	serine/threonine protein kinase	0.00970412	0.0414115	0.0717227
Loa Loa (eye worm)	phosphatidylinositol glycan anchor biosynthesis protein	0.0064607	0.0191906	0.0233347
Schistosoma mansoni	protein kinase	0.00375351	0.000643539	0.000633558
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Leishmania major	N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase	0.0064607	0.0191906	0.0963619
Loa Loa (eye worm)	hypothetical protein	0.00899702	0.0365671	0.0447765
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0117375	0.055342	0.096014
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.00475252	0.00748779	0.0125682
Schistosoma mansoni	serine/threonine-protein kinase	0.00544002	0.0121979	0.0207814
Echinococcus granulosus	nervana 2	0.00419369	0.0036592	0.00589211
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.00375351	0.000643539	0.000633558
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Schistosoma mansoni	serine/threonine-protein kinase	0.00544002	0.0121979	0.0207814
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Brugia malayi	SH2 domain containing protein	0.00429599	0.00436011	0.00711433
Echinococcus multilocularis	nervana 2	0.00419369	0.0036592	0.00589211
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Trichomonas vaginalis	CMGC family protein kinase	0.00970412	0.0414115	0.209593
Echinococcus multilocularis	transmembrane protease serine 3	0.00495918	0.0089036	0.015037
Trypanosoma cruzi	N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative	0.0064607	0.0191906	0.0963619
Trypanosoma brucei	cdc2-related kinase 1	0.00970412	0.0414115	0.209593
Echinococcus multilocularis	casein kinase ii subunit alpha	0.0279297	0.166276	0.289455
Echinococcus multilocularis	proto oncogene serine:threonine protein kinase	0.0162045	0.085946	0.14938
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.00429599	0.00436011	0.00711433
Loa Loa (eye worm)	AUR protein kinase	0.0238661	0.138436	0.170479
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Schistosoma mansoni	neuroglian	0.00475252	0.00748779	0.0125682
Trypanosoma brucei	N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase	0.0064607	0.0191906	0.0963619
Echinococcus granulosus	nervana 2	0.00419369	0.0036592	0.00589211
Schistosoma mansoni	kinase	0.0525357	0.334854	0.583412
Echinococcus granulosus	tyrosine protein kinase shark	0.00429599	0.00436011	0.00711433
Echinococcus granulosus	transmembrane protease serine 3	0.00495918	0.0089036	0.015037
Trypanosoma brucei	Casein kinase II	0.0279297	0.166276	0.845865
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Echinococcus granulosus	twitchin	0.00953093	0.040225	0.0696537
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.00375351	0.000643539	0.000633558
Loa Loa (eye worm)	hypothetical protein	0.00698006	0.0227488	0.0277253
Loa Loa (eye worm)	hypothetical protein	0.00813561	0.0306655	0.0374942
Brugia malayi	Protein kinase domain containing protein	0.0610186	0.39297	0.684754
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.00970412	0.0414115	0.0507543
Schistosoma mansoni	tyrosine kinase	0.0602798	0.387909	0.675927
Brugia malayi	cell division control protein 2 homolog	0.00970412	0.0414115	0.0717227
Plasmodium falciparum	protein kinase, putative	0.00375351	0.000643539	0.0021888
Trypanosoma cruzi	Protein kinase B	0.00544002	0.0121979	0.0607289
Brugia malayi	Protein kinase domain containing protein	0.00970412	0.0414115	0.0717227
Echinococcus granulosus	serine/threonine protein kinase	0.00544002	0.0121979	0.0207814
Loa Loa (eye worm)	TK/INSR protein kinase	0.0750922	0.489389	0.60354
Brugia malayi	Protein kinase domain containing protein	0.00429599	0.00436011	0.00711433
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Echinococcus granulosus	tyrosine kinase	0.0102617	0.0452313	0.0783834
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.00516456	0.0103107	0.0511125
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.00544002	0.0121979	0.0607289
Echinococcus multilocularis	neuroglian	0.00856006	0.0335735	0.0580551
Echinococcus multilocularis	tyrosine protein kinase HCK	0.00874831	0.0348632	0.0603041
Echinococcus granulosus	ephrin type A receptor 4 A	0.0166073	0.0887058	0.154192
Loa Loa (eye worm)	hypothetical protein	0.00475252	0.00748779	0.00889385
Entamoeba histolytica	protein kinase , putative	0.0238661	0.138436	0.704003
Brugia malayi	Trypsin family protein	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	hypothetical protein	0.010577	0.0473918	0.0581338
Brugia malayi	Protein kinase domain containing protein	0.00429599	0.00436011	0.00711433
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00370643	0.000320959	0.000071059
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0117375	0.055342	0.096014
Echinococcus granulosus	neuroglian	0.00856006	0.0335735	0.0580551
Brugia malayi	plexin A	0.00406685	0.00279021	0.00437681
Trypanosoma cruzi	polo-like protein kinase, putative	0.0323448	0.196524	1
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.00375351	0.000643539	0.00185143
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Entamoeba histolytica	protein kinase, putative	0.0238661	0.138436	0.704003
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0162045	0.085946	0.105708
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.00495918	0.0089036	0.015037
Giardia lamblia	Aurora kinase	0.0238661	0.138436	0.704003
Loa Loa (eye worm)	hypothetical protein	0.00698006	0.0227488	0.0277253
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0323448	0.196524	0.242157
Onchocerca volvulus	Tyrosine kinase homolog	0.067897	0.440095	1
Entamoeba histolytica	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative	0.0064607	0.0191906	0.0963619
Toxoplasma gondii	N-acetylglucosaminylphosphatidylinositol deacetylase	0.0064607	0.0191906	0.111977
Brugia malayi	Protein kinase domain containing protein	0.00429599	0.00436011	0.00711433
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0166073	0.0887058	0.154192
Entamoeba histolytica	casein kinase, putative	0.0279297	0.166276	0.845865
Loa Loa (eye worm)	CAMK/CAMKL/NUAK protein kinase	0.121989	0.81068	1
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Schistosoma mansoni	serine/threonine protein kinase	0.0323448	0.196524	0.3422
Schistosoma mansoni	tyrosine kinase	0.0563866	0.361236	0.629417
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Echinococcus granulosus	roundabout 2	0.0117326	0.0553086	0.0959557
Plasmodium vivax	protein kinase Crk2	0.00970412	0.0414115	0.249053
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0323448	0.196524	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.00436264	0.00481672	0.00791055
Loa Loa (eye worm)	hypothetical protein	0.00813561	0.0306655	0.0374942
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.00370643	0.000320959	0.0000502846
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Trypanosoma cruzi	cdc2-related kinase 3	0.00970412	0.0414115	0.209593
Leishmania major	protein kinase, putative	0.00375351	0.000643539	0.00185143
Brugia malayi	Immunoglobulin I-set domain containing protein	0.00436264	0.00481672	0.00791055
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Onchocerca volvulus		0.00495918	0.0089036	0.0196069
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Loa Loa (eye worm)	TK/EPH protein kinase	0.0170086	0.0914548	0.112506
Loa Loa (eye worm)	hypothetical protein	0.010577	0.0473918	0.0581338
Echinococcus multilocularis	protein tyrosine kinase	0.0602798	0.387909	0.675927
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.00970412	0.0414115	0.0507543
Schistosoma mansoni	N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase	0.0064607	0.0191906	0.032975
Trichomonas vaginalis	CAMK family protein kinase	0.0109083	0.0496615	0.251632
Echinococcus multilocularis	neuroglian	0.00475252	0.00748779	0.0125682
Brugia malayi	Fibronectin type III domain containing protein	0.00813561	0.0306655	0.0529844
Loa Loa (eye worm)	TK protein kinase	0.0102617	0.0452313	0.0554678
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Echinococcus multilocularis	Serine:threonine protein kinase PLK4	0.0310993	0.187991	0.327321
Loa Loa (eye worm)	hypothetical protein	0.00813561	0.0306655	0.0374942
Loa Loa (eye worm)	hypothetical protein	0.0292112	0.175056	0.215666
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0238661	0.138436	0.704003
Echinococcus granulosus	titin	0.00370643	0.000320959	0.000071059
Plasmodium vivax	casein kinase 2, alpha subunit, putative	0.0279297	0.166276	1
Brugia malayi	Protein kinase domain containing protein	0.0319939	0.19412	0.338008
Brugia malayi	SH2 domain containing protein	0.00429599	0.00436011	0.00711433
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.00577178	0.0144708	0.0247449
Echinococcus granulosus	titin	0.00370643	0.000320959	0.000071059
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Echinococcus granulosus	roundabout 2	0.00475252	0.00748779	0.0125682
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0117375	0.055342	0.096014
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0591692	0.3803	0.66266
Leishmania major	cell division related protein kinase 2,cdc2-related kinase	0.00970412	0.0414115	0.209593
Entamoeba histolytica	protein kinase, putative	0.00757922	0.0268537	0.135411
Plasmodium falciparum	N-acetylglucosaminylphosphatidylinositol deacetylase, putative	0.0064607	0.0191906	0.113921
Trichomonas vaginalis	AGC family protein kinase	0.0238661	0.138436	0.704003
Trichomonas vaginalis	CMGC family protein kinase	0.0279297	0.166276	0.845865
Echinococcus granulosus	protein tyrosine kinase	0.0602798	0.387909	0.675927
Onchocerca volvulus		0.00429599	0.00436011	0.00927641
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0117375	0.055342	0.096014
Echinococcus multilocularis	nervana 2	0.00419369	0.0036592	0.00589211
Loa Loa (eye worm)	TK/FER protein kinase	0.00429599	0.00436011	0.00503443
Schistosoma mansoni	protein kinase	0.00375351	0.000643539	0.000633558
Loa Loa (eye worm)	AGC/AKT protein kinase	0.00757922	0.0268537	0.0327906
Entamoeba histolytica	protein kinase domain containing protein	0.00375351	0.000643539	0.00185143
Leishmania major	casein kinase II, putative	0.0279297	0.166276	0.845865
Brugia malayi	Protein kinase domain containing protein	0.00429599	0.00436011	0.00711433
Schistosoma mansoni	protein kinase	0.0279297	0.166276	0.289455
Brugia malayi	p70 ribosomal S6 kinase beta	0.00730377	0.0249665	0.0430468
Echinococcus granulosus	casein kinase ii subunit alpha	0.0279297	0.166276	0.289455
Echinococcus granulosus	neuroglian	0.00475252	0.00748779	0.0125682
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.00730377	0.0249665	0.0304619
Echinococcus granulosus	epidermal growth factor receptor	0.0874067	0.573757	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.00436264	0.00481672	0.00559787
Brugia malayi	Protein kinase domain containing protein	0.0750922	0.489389	0.852884
Echinococcus granulosus	activin receptor type	0.00375351	0.000643539	0.000633558
Schistosoma mansoni	cercarial elastase (S01 family)	0.00495918	0.0089036	0.015037
Echinococcus multilocularis	epidermal growth factor receptor	0.0874067	0.573757	1
Schistosoma mansoni	tyrosine kinase	0.0117375	0.055342	0.096014
Echinococcus multilocularis	titin	0.00370643	0.000320959	0.000071059
Brugia malayi	hypothetical protein	0.00813561	0.0306655	0.0529844
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.00475252	0.00748779	0.0125682
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0117375	0.055342	0.096014
Onchocerca volvulus	Serine\/threonine protein kinase homolog	0.0162045	0.085946	0.194777
Schistosoma mansoni	hypothetical protein	0.00495918	0.0089036	0.015037
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0238661	0.138436	0.832571
Trichomonas vaginalis	glucosamine-6-phosphate isomerase, putative	0.0064607	0.0191906	0.0963619
Trichomonas vaginalis	CAMK family protein kinase	0.0323448	0.196524	1
Trypanosoma brucei	polo-like protein kinase	0.0323448	0.196524	1
Echinococcus granulosus	Glutaredoxin protein 5	0.00419369	0.0036592	0.00589211
Loa Loa (eye worm)	SRC-1	0.0117375	0.055342	0.067944
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.00495918	0.0089036	0.015037
Brugia malayi	Serine/threonine-protein kinase Pim-3	0.0162045	0.085946	0.14938
Brugia malayi	Protein kinase domain containing protein	0.0162045	0.085946	0.14938
Loa Loa (eye worm)	hypothetical protein	0.00429599	0.00436011	0.00503443
Echinococcus multilocularis	Mastin	0.00495918	0.0089036	0.015037
Loa Loa (eye worm)	CMGC/CK2 protein kinase	0.0279297	0.166276	0.204832
Echinococcus multilocularis	serine threonine protein kinase nrc serine threonine protein kinase gad	0.00516456	0.0103107	0.0174907
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0117375	0.055342	0.096014
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0117375	0.055342	0.096014
Loa Loa (eye worm)	hypothetical protein	0.00698006	0.0227488	0.0277253
Loa Loa (eye worm)	hypothetical protein	0.00495918	0.0089036	0.0106409
Echinococcus multilocularis	epidermal growth factor receptor	0.0591692	0.3803	0.66266
Schistosoma mansoni	serine/threonine protein kinase	0.0238661	0.138436	0.24091
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.00475252	0.00748779	0.0125682
Echinococcus granulosus	tyrosine protein kinase ABL1	0.00429599	0.00436011	0.00711433
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.00375351	0.000643539	0.00185143
Echinococcus multilocularis	roundabout 2	0.00475252	0.00748779	0.0125682
Echinococcus multilocularis	rac serine:threonine kinase	0.00544002	0.0121979	0.0207814
Brugia malayi	protein unc-22	0.00370643	0.000320959	0.000071059
Trichomonas vaginalis	AGC family protein kinase	0.00757922	0.0268537	0.135411
Trichomonas vaginalis	AGC family protein kinase	0.0238661	0.138436	0.704003
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.00577178	0.0144708	0.0247449
Entamoeba histolytica	protein kinase, putative	0.0238661	0.138436	0.704003
Brugia malayi	Trypsin-like protease protein 5	0.00495918	0.0089036	0.015037
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.00698006	0.0227488	0.0391796
Toxoplasma gondii	CMGC kinase, CK2 family	0.0279297	0.166276	1
Entamoeba histolytica	protein kinase, putative	0.00757922	0.0268537	0.135411
Plasmodium vivax	rac-beta serine/threonine protein kinase, putative	0.00516456	0.0103107	0.0620097
Echinococcus granulosus	cyclin dependent kinase	0.00970412	0.0414115	0.0717227
Schistosoma mansoni	tyrosine kinase	0.00429599	0.00436011	0.00711433
Loa Loa (eye worm)	TK protein kinase	0.00874831	0.0348632	0.042674
Echinococcus multilocularis	tyrosine protein kinase Abl	0.00577178	0.0144708	0.0247449
Brugia malayi	ephrin receptor 1 precursor	0.00804429	0.0300399	0.0518934
Echinococcus multilocularis	insulin receptor	0.0750922	0.489389	0.852884
Echinococcus granulosus	insulin receptor	0.0750922	0.489389	0.852884
Trypanosoma cruzi	aurora B kinase, putative	0.0238661	0.138436	0.704003
Echinococcus multilocularis	plexin a4	0.00406685	0.00279021	0.00437681
Giardia lamblia	Kinase, CMGC CK2	0.0279297	0.166276	0.845865

Activities

Activity type	Activity value	Assay description	Source	Reference
ED50 (functional)	= 0.9 mg kg-1	Effective dose after subcutaneous administration in a mouse malaria model against Plasmodium berghei N strain for 50% inhibition	ChEMBL.	12213073
ED50 (functional)	= 1.5 mg kg-1	Effective dose after oral administration against Plasmodium yoelii sspNS for 50%inhibition in presence of DMSO	ChEMBL.	12213073
ED50 (functional)	= 2.6 mg kg-1	Effective dose after peroral administration in a mouse malaria model against Plasmodium berghei N strain for 50% inhibition	ChEMBL.	12213073
ED50 (functional)	= 4.2 mg kg-1	Effective dose after oral administration against Plasmodium yoelii sspNS for 50%inhibition in presence of SSV	ChEMBL.	12213073
ED90 (functional)	= 1.7 mg kg-1	Effective dose after subcutaneous administration in a mouse malaria model against Plasmodium berghei N strain for 90% inhibition	ChEMBL.	12213073
ED90 (functional)	= 3.6 mg kg-1	Effective dose after oral administration against Plasmodium yoelii sspNS for 90%inhibition in presence of DMSO	ChEMBL.	12213073
ED90 (functional)	= 5 mg kg-1	Effective dose after peroral administration in a mouse malaria model against Plasmodium berghei N strain for 90% inhibition	ChEMBL.	12213073
ED90 (functional)	= 12 mg kg-1	Effective dose after oral administration against Plasmodium yoelii sspNS for 90%inhibition in presence of SSV	ChEMBL.	12213073
IC50 (functional)	= 0.78 ng ml-1	Inhibitory activity against Plasmodium falciparum D6 strain	ChEMBL.	12213073
IC50 (functional)	= 4.06 ng ml-1	Inhibitory activity against Plasmodium falciparum K1 strain	ChEMBL.	12213073
IC50 (functional)	= 7.11 ng ml-1	Inhibitory activity against Plasmodium falciparum W2 strain	ChEMBL.	12213073
NT (functional)		Inhibitory activity against Plasmodium falciparum NF54 strain; Not tested	ChEMBL.	12213073

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Plasmodium falciparum	ChEMBL23	12213073

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL578785

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1080066