Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 2 (macrophage) | Starlite/ChEMBL | References |
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.3599 | 0.2673 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4357 | 0.4709 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4024 | 0.4348 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0518 | 0.0242 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.7956 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0851 | 0.0679 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0518 | 0.0559 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7332 | 0.9752 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3186 | 0.3975 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.3611 | 0.3902 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.9254 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.9414 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0066 | 0.7509 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3186 | 0.3975 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.7509 | 0.9414 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0851 | 0.0721 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0066 | 0.7509 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0066 | 0.7509 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0851 | 0.0721 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7332 | 0.9752 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.