TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 434.612 | Formula: C25H42N2O4
H donors: 5 H acceptors: 4 LogP: 3.89 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: ONC(=O)NCCCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CCC/C/2=C\C=C\1/C[C@@H](O)C[C@@H](C1)O)C
InChi: 1S/C25H42N2O4/c1-17(6-3-4-13-26-24(30)27-31)22-10-11-23-19(7-5-12-25(22,23)2)9-8-18-14-20(28)16-21(29)15-18/h8-9,17,20-23,28-29,31H,3-7,10-16H2,1-2H3,(H2,26,27,30)/b19-9+/t17-,20-,21-,22-,23+,25-/m1/s1
InChiKey: MBTDKBOCJRSRAL-VPZVJBPJSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	protein kinase, putative	0.0034	0.0597	0.1495
Trichomonas vaginalis	sugar transporter, putative	0.0034	0.0606	0.1519
Trichomonas vaginalis	sugar transporter, putative	0.0034	0.0606	0.1519
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Schistosoma mansoni	lysyl-tRNA synthetase	0.0025	0.0399	0.1769
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0025	0.0399	0.3504
Echinococcus granulosus	synaptic vesicle 2 protein	0.0016	0.0201	0.0894
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.0021	0.0318	0.117
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0201	0.0505
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0016	0.0201	0.0894
Trypanosoma brucei	glucose transporter 1E	0.0034	0.0606	0.5329
Schistosoma mansoni	protein kinase	0.0034	0.0597	0.2648
Trypanosoma cruzi	hypothetical protein, conserved	0.0059	0.1138	1
Trichomonas vaginalis	sugar transporter, putative	0.0034	0.0606	0.1519
Brugia malayi	Sugar transporter family protein	0.0016	0.0201	0.0505
Schistosoma mansoni	serine/threonine protein kinase	0.0034	0.0597	0.2648
Trichomonas vaginalis	conserved hypothetical protein	0.0034	0.0606	0.1519
Giardia lamblia	Low molecular weight protein-tyrosine-phosphatase	0.0192	0.3992	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0399	0.0999
Brugia malayi	hypothetical protein	0.0016	0.0201	0.0505
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0192	0.3992	1
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.018	0.3724	0.3724
Brugia malayi	Cam kinase protein 1	0.0034	0.0597	0.1495
Brugia malayi	Sugar transporter family protein	0.0111	0.2253	0.5645
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Brugia malayi	major facilitator superfamily protein	0.0016	0.0201	0.0505
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0034	0.0597	0.2648
Schistosoma mansoni	glucose transport protein	0.0111	0.2253	1
Entamoeba histolytica	hypothetical protein	0.0025	0.0399	0.0999
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0033	0.0582	0.2583
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0033	0.0582	0.1458
Trichomonas vaginalis	conserved hypothetical protein	0.0034	0.0606	0.1519
Toxoplasma gondii	lysine-tRNA ligase	0.0025	0.0399	0.0603
Schistosoma mansoni	glucose transport protein	0.0111	0.2253	1
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0025	0.0399	0.3504
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0033	0.0582	1
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0016	0.0201	1
Echinococcus granulosus	calcium dependent protein kinase	0.0032	0.0552	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0582	0.1458
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0034	0.0597	0.0597
Echinococcus granulosus	solute carrier family 22	0.0016	0.0201	0.0894
Loa Loa (eye worm)	sugar transporter	0.0111	0.2253	0.5645
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0201	0.0505
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0039	0.0701	0.616
Mycobacterium ulcerans	prolyl-tRNA synthetase	0.0012	0.0119	0.0297
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Toxoplasma gondii	sugar transporter ST1	0.0016	0.0201	0.0305
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Echinococcus granulosus	solute carrier family 22	0.0016	0.0201	0.0894
Plasmodium falciparum	mitogen-activated protein kinase 2	0.018	0.3724	0.3724
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0192	0.3992	1
Leishmania major	protein kinase, putative	0.0034	0.0597	0.5246
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Trypanosoma cruzi	glucose transporter, putative	0.0016	0.0201	0.177
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0016	0.0201	0.177
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0597	0.1495
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Trichomonas vaginalis	glucose transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0025	0.0399	0.0999
Echinococcus multilocularis	lysyl tRNA synthetase	0.0025	0.0399	0.1769
Leishmania major	hypothetical protein, conserved	0.0016	0.0201	0.177
Chlamydia trachomatis	lysine--tRNA ligase	0.0025	0.0399	1
Trypanosoma cruzi	hexose transporter, putative	0.0016	0.0201	0.177
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Plasmodium falciparum	hexose transporter	0.0111	0.2253	0.2253
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Toxoplasma gondii	sugar transporter ST3	0.0016	0.0201	0.0305
Mycobacterium ulcerans	sugar transporter	0.0016	0.0201	0.0505
Plasmodium vivax	hexose transporter	0.0111	0.2253	0.2253
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0016	0.0201	0.0505
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0016	0.0201	0.0201
Trichomonas vaginalis	CAMK family protein kinase	0.0034	0.0597	0.1495
Schistosoma mansoni	sugar transporter	0.0016	0.0201	0.0894
Echinococcus granulosus	solute carrier family 22	0.0016	0.0201	0.0894
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0192	0.3992	1
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Mycobacterium tuberculosis	Probable conserved integral membrane transport protein	0.0016	0.0201	0.074
Mycobacterium leprae	Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0021	0.0318	0.5469
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0016	0.0201	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transport protein, putative	0.0016	0.0201	0.0505
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Trichomonas vaginalis	glucose transporter, putative	0.0034	0.0606	0.1519
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0033	0.0582	0.2583
Trypanosoma cruzi	hexose transporter, putative	0.0034	0.0606	0.5329
Brugia malayi	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2253	0.5645
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0034	0.0597	0.0597
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0034	0.0597	0.0597
Trypanosoma brucei	glucose transporter 2A	0.0034	0.0606	0.5329
Mycobacterium tuberculosis	Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase)	0.0133	0.272	1
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0034	0.0597	0.1495
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0022	0.0333	0.0834
Schistosoma mansoni	sugar transporter	0.0016	0.0201	0.0894
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0016	0.0201	0.0894
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0034	0.0597	0.0903
Giardia lamblia	Prolyl-tRNA synthetase	0.0033	0.0582	0.1458
Trypanosoma cruzi	hexose transporter, putative	0.0034	0.0606	0.5329
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0033	0.0582	0.1458
Schistosoma mansoni	glucose transporter	0.0016	0.0201	0.0894
Plasmodium falciparum	proline--tRNA ligase	0.0039	0.0701	0.0701
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0034	0.0597	0.0597
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0021	0.0318	0.117
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0111	0.2253	1
Schistosoma mansoni	hypothetical protein	0.0111	0.2253	1
Leishmania major	hypothetical protein, conserved	0.0059	0.1138	1
Plasmodium falciparum	lysine--tRNA ligase	0.0025	0.0399	0.0399
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0192	0.3992	1
Mycobacterium tuberculosis	Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	0.0016	0.0201	0.074
Echinococcus granulosus	solute carrier family 22	0.0016	0.0201	0.0894
Echinococcus granulosus	lysyl tRNA synthetase	0.0025	0.0399	0.1769
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0201	0.0894
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0039	0.0701	0.106
Loa Loa (eye worm)	phosphotyrosine protein phosphatase	0.0192	0.3992	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Giardia lamblia	Hexose transporter	0.0016	0.0201	0.0505
Schistosoma mansoni	protein kinase	0.0034	0.0597	0.2648
Brugia malayi	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0034	0.0597	0.0597
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0034	0.0597	0.0597
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0472	1	1
Onchocerca volvulus		0.0192	0.3992	1
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Trypanosoma cruzi	hypothetical protein, conserved	0.0059	0.1138	1
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0201	0.0894
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0201	0.0505
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0025	0.0399	0.6849
Trypanosoma brucei	low molecular weight protein tyrosine phosphatase, putative	0.0059	0.1138	1
Toxoplasma gondii	facilitative glucose transporter GT1	0.0111	0.2253	0.3408
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0582	0.1458
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0034	0.0606	0.5329
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0059	0.1138	0.285
Echinococcus multilocularis	General substrate transporter	0.0096	0.1918	0.851
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0033	0.0582	0.2583
Trypanosoma cruzi	hexose transporter	0.0034	0.0606	0.5329
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0033	0.0582	0.1458
Mycobacterium ulcerans	integral membrane transport protein	0.0016	0.0201	0.0505
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0201	0.0505
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0039	0.0701	0.616
Treponema pallidum	prolyl-tRNA synthetase	0.0012	0.0119	1
Chlamydia trachomatis	proline--tRNA ligase	0.0012	0.0119	0.2978
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0025	0.0399	0.0999
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0014	0.016	0.04
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Brugia malayi	major facilitator superfamily protein	0.0016	0.0201	0.0505
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0039	0.0701	0.616
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0034	0.0597	0.0597
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0034	0.0597	0.0903
Plasmodium vivax	proline--tRNA ligase, putative	0.0039	0.0701	0.0701
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0039	0.0701	0.616
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0034	0.0597	0.5246
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trypanosoma brucei	sugar transporter, putative	0.0016	0.0201	0.177
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Leishmania major	myo-inositol/proton symporter (MIT)	0.0016	0.0201	0.177
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0034	0.0606	0.5329
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0039	0.0701	0.616
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.018	0.3724	0.5632
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0192	0.3992	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Leishmania major	glucose transporter, lmgt3	0.0034	0.0606	0.5329
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0192	0.3992	1
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Toxoplasma gondii	protein kinase, putative	0.0314	0.6612	1
Giardia lamblia	Lysyl-tRNA synthetase	0.0025	0.0399	0.0999
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Brugia malayi	Low molecular weight phosphotyrosine protein phosphatase containing protein	0.0192	0.3992	1
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0448	0.1121
Schistosoma mansoni	lysyl-tRNA synthetase	0.0025	0.0399	0.1769
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0034	0.0597	0.1495
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Giardia lamblia	Sugar-proton symporter	0.0016	0.0201	0.0505
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Loa Loa (eye worm)	sugar transporter	0.0016	0.0201	0.0505
Leishmania major	glucose transporter, lmgt2	0.0034	0.0606	0.5329
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trypanosoma brucei	glucose transporter, putative	0.0034	0.0606	0.5329
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0025	0.0399	0.0999
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0034	0.0597	0.0903
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0033	0.0582	0.1458
Trypanosoma cruzi	hexose transporter, putative	0.0019	0.027	0.2377
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	myo-inositol transporter, putative	0.0016	0.0201	0.0505
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	glucose transporter, putative	0.0034	0.0606	0.1519
Brugia malayi	Sugar transporter family protein	0.0016	0.0201	0.0505
Plasmodium vivax	sugar transporter, putative	0.0016	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0016	0.0201	0.0505
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Leishmania major	lysyl-tRNA synthetase, putative	0.0025	0.0399	0.3504
Plasmodium vivax	lysine--tRNA ligase, putative	0.0025	0.0399	0.0399
Toxoplasma gondii	transporter, major facilitator family protein	0.0016	0.0201	0.0305
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Trypanosoma cruzi	hexose transporter, putative	0.0034	0.0606	0.5329
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0033	0.0582	0.2583
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0201	0.0894
Schistosoma mansoni	sugar transporter	0.0016	0.0201	0.0894
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0034	0.0606	0.5329
Schistosoma mansoni	protein kinase	0.0034	0.0597	0.2648
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0034	0.0606	0.5329
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0034	0.0597	0.0597
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0034	0.0597	0.1495
Trypanosoma cruzi	sugar transporter, putative	0.0016	0.0201	0.177
Echinococcus multilocularis	calcium dependent protein kinase	0.0032	0.0552	0.2448
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0016	0.0201	0.0894
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0034	0.0597	0.2648
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Plasmodium falciparum	protein kinase 7	0.0314	0.6612	0.6612
Mycobacterium ulcerans	phosphotyrosine protein phosphatase PtpA	0.0192	0.3992	1
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0111	0.2253	1
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0016	0.0201	0.0505
Trichomonas vaginalis	sugar transporter, putative	0.0016	0.0201	0.0505
Brugia malayi	lysyl-tRNA synthetase	0.0025	0.0399	0.0999
Echinococcus granulosus	General substrate transporter	0.0096	0.1918	0.851
Entamoeba histolytica	protein kinase, putative	0.0034	0.0597	0.1495
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0016	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0201	0.0505
Schistosoma mansoni	glucose transport protein	0.0111	0.2253	1
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0192	0.3992	1
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0201	0.0505
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0192	0.3992	1
Schistosoma mansoni	sugar transporter	0.0016	0.0201	0.0894
Leishmania major	glucose transporter, lmgt1	0.0034	0.0606	0.5329
Toxoplasma gondii	sugar transporter ST2	0.0016	0.0201	0.0305
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0059	0.1138	0.285
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0034	0.0597	0.0597

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1164779

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1137133