Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chromobox protein | 0.0068 | 0.888 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3392 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.736 | 0.8288 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3392 | 0.5 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0435 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4087 | 0.4413 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3667 | 0.2673 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.888 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0618 | 0.0667 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0947 | 0.1067 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0947 | 0.1067 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.284 | 0.3198 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.7978 | 0.8984 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0435 | 0.049 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.3684 | 0.2694 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.5517 | 0.4813 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9262 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.3392 | 0.382 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.4188 | 0.3419 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.736 | 0.8288 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.3684 | 0.2714 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.5517 | 0.4813 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.888 | 0.8704 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3392 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.888 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.3392 | 0.382 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.3684 | 0.2714 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.888 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3392 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.5517 | 0.5956 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.2253 | 0.2432 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.888 | 1 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0618 | 0.0696 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.4188 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.284 | 0.1717 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3679 | 0.3972 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3258 | 0.3669 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.3392 | 0.382 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.888 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3684 | 0.3978 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.888 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.888 | 0.9588 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0947 | 0.1067 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0106 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4417 | 0.4769 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.4188 | 0.3419 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.284 | 0.3066 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0435 | 0.049 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.3684 | 0.7399 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.888 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.3392 | 0.382 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.5517 | 0.5956 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3258 | 0.3669 |
Brugia malayi | hypothetical protein | 0.0036 | 0.3392 | 0.2356 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.