Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.4951 | 0.6727 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3679 | 0.3972 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.4951 | 0.6206 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.4417 | 0.4769 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3258 | 0.4427 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.4951 | 0.6727 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0947 | 0.1188 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0618 | 0.0667 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.736 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0106 | 0.0114 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0435 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.9262 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.4951 | 0.6206 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3258 | 0.4427 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.7978 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.4951 | 0.6727 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.4951 | 0.6727 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4087 | 0.4413 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.736 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.4951 | 0.6206 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0435 | 0.0592 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0947 | 0.1287 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0435 | 0.0592 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.4951 | 0.5346 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0618 | 0.0774 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.3667 | 0.2673 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.4951 | 0.4159 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0947 | 0.1287 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.