Detailed information for compound 1183155

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 692.666 | Formula: C42H28O10
  • H donors: 5 H acceptors: 7 LogP: 4.9 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: Oc1ccc(cc1)[C@@H]1OC2=CC(=O)C(=O)C3=C2[C@H]1c1cc(O)cc2c1[C@H]([C@@H](O2)c1ccc(cc1)O)c1c2[C@H]3[C@H](Oc2cc(c1)O)c1ccc(cc1)O
  • InChi: 1S/C42H28O10/c43-21-7-1-18(2-8-21)40-34-27-14-25(47)16-30-33(27)38(42(51-30)20-5-11-23(45)12-6-20)37-36-31(17-28(48)39(37)49)52-41(19-3-9-22(44)10-4-19)35(36)26-13-24(46)15-29(50-40)32(26)34/h1-17,34-35,38,40-47H/t34-,35-,38-,40+,41+,42-/m1/s1
  • InChiKey: PEVCENMPFGEBKL-MGZRWOOSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0196 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.209 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0126 0.0048
Brugia malayi beta-lactamase 0.0042 0.0693 0.217
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0126 0.5
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0693 0.1902
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.1018 0.2958
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0384 0.0897
Plasmodium vivax glutathione reductase, putative 0.0055 0.1018 0.0923
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0693 0.217
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0108 0.0338
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0126 0.0631
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Schistosoma mansoni hypothetical protein 0.0099 0.209 0.4691
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.003 0.0399 0.0457
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.003 0.0399 0.0457
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0126 0.002
Mycobacterium tuberculosis Conserved protein 0.0042 0.0693 0.0935
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.1352 0.2945
Loa Loa (eye worm) hypothetical protein 0.003 0.0384 0.0902
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.1352 0.2945
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0126 0.2769 0.4292
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0505 0.4375
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0022 0.0196 0.0273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0917 0.1918
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0408 0.3597
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0126 0.5
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.1352 0.2945
Plasmodium falciparum thioredoxin reductase 0.0019 0.0126 0.002
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0126 0.0631
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0384 0.0658
Brugia malayi jmjC domain containing protein 0.0018 0.0105 0.033
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0126 0.0222
Schistosoma mansoni hypothetical protein 0.004 0.0637 0.1256
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0384 0.0658
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0006
Echinococcus granulosus GPCR family 2 0.0018 0.0108 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.1352 0.2945
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0384 0.9253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0693 0.0935
Brugia malayi lysyl-tRNA synthetase 0.0022 0.0196 0.0615
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0126 0.0222
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0505 0.461
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0505 0.0621
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0693 0.1388
Mycobacterium ulcerans beta-lactamase 0.0042 0.0693 1
Trichomonas vaginalis esterase, putative 0.0042 0.0693 0.2885
Plasmodium falciparum calcium-dependent protein kinase 2 0.003 0.0399 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0693 0.658
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0408 0.1439
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0693 0.2885
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.014 0.3117 0.4855
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0917 0.1918
Echinococcus granulosus lysyl tRNA synthetase 0.0022 0.0196 0.0215
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0408 0.3318
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0022 0.0196 0.0997
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0384 0.1202
Schistosoma mansoni protein kinase 0.003 0.0399 0.0693
Mycobacterium ulcerans lipase LipD 0.0042 0.0693 1
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0126 0.0032
Mycobacterium tuberculosis Conserved protein 0.0042 0.0693 0.0935
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0384 0.1202
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0196 0.1248
Entamoeba histolytica protein kinase, putative 0.003 0.0399 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Plasmodium falciparum glutathione reductase 0.0019 0.0126 0.002
Trypanosoma brucei glucose transporter 2A 0.0031 0.0408 0.3318
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.1018 0.2158
Schistosoma mansoni jumonji domain containing protein 0.0069 0.1352 0.2945
Echinococcus multilocularis General substrate transporter 0.0085 0.1747 0.3881
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.016 0.3592 0.5418
Plasmodium falciparum protein kinase 7 0.0279 0.6541 0.6504
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.1352 0.2945
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0384 0.0658
Plasmodium falciparum calcium-dependent protein kinase 3 0.003 0.0399 0.0297
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0126 0.002
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.003 0.0399 0.0297
Schistosoma mansoni glucose transport protein 0.0099 0.209 0.4691
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Leishmania major trypanothione reductase 0.0055 0.1018 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0126 0.2769 0.4292
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.016 0.3592 0.3524
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0126 0.002
Echinococcus multilocularis lysyl tRNA synthetase 0.0022 0.0196 0.0215
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0006
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0505 0.461
Schistosoma mansoni glucose transport protein 0.0099 0.209 0.4691
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0384 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0693 0.0935
Onchocerca volvulus Huntingtin homolog 0.0143 0.3192 1
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.1018 0.0923
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0126 0.0222
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0408 0.1439
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0126 0.0222
Toxoplasma gondii ABC1 family protein 0.0042 0.0693 0.0912
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.1018 0.1462
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0637 0.1995
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.003 0.0399 0.0297
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0196 0.0215
Plasmodium falciparum glutathione reductase 0.0055 0.1018 0.0923
Trypanosoma brucei glucose transporter 1E 0.0031 0.0408 0.3318
Brugia malayi hypothetical protein 0.0143 0.3192 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0693 0.1388
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0408 0.1439
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0126 0.002
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0196 0.0215
Echinococcus multilocularis calcium dependent protein kinase 0.0028 0.0353 0.0584
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0917 0.2629
Brugia malayi Thioredoxin reductase 0.0055 0.1018 0.3191
Loa Loa (eye worm) hypothetical protein 0.0143 0.3192 1
Loa Loa (eye worm) glutathione reductase 0.0055 0.1018 0.2958
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0019 0.0129 0.0019
Mycobacterium ulcerans hypothetical protein 0.0042 0.0693 1
Echinococcus granulosus geminin 0.019 0.4337 1
Echinococcus granulosus General substrate transporter 0.0085 0.1747 0.3881
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0105 0.0418
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.003 0.0399 0.095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0126 0.0048
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0126 0.0048
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0006
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0384 0.1313
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0693 1
Mycobacterium tuberculosis Conserved protein 0.0042 0.0693 0.0935
Brugia malayi jmjC domain containing protein 0.0069 0.1352 0.4234
Trypanosoma cruzi hexose transporter 0.0031 0.0408 0.3597
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Brugia malayi jmjC domain containing protein 0.0018 0.0105 0.033
Mycobacterium tuberculosis Probable reductase 0.0126 0.2769 0.4292
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.014 0.3117 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0693 0.2885
Trypanosoma brucei trypanothione reductase 0.0055 0.1018 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0126 0.2769 0.8842
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0408 0.1439
Brugia malayi jmjC domain containing protein 0.0018 0.0105 0.033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Plasmodium vivax hexose transporter 0.0099 0.209 0.2006
Plasmodium falciparum thioredoxin reductase 0.0055 0.1018 0.0923
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0693 0.0935
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0917 0.1918
Brugia malayi beta-lactamase family protein 0.0042 0.0693 0.217
Loa Loa (eye worm) beta-lactamase 0.0042 0.0693 0.1902
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0693 0.0935
Loa Loa (eye worm) hypothetical protein 0.0143 0.3192 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0126 0.0222
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0126 0.0032
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.003 0.0399 0.0693
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0126 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0693 1
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0693 0.0935
Chlamydia trachomatis lysine--tRNA ligase 0.0022 0.0196 1
Onchocerca volvulus Huntingtin homolog 0.0143 0.3192 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0631
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0105 0.0418
Loa Loa (eye worm) hypothetical protein 0.003 0.0399 0.095
Toxoplasma gondii protein kinase, putative 0.0279 0.6541 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.003 0.0399 0.0297
Brugia malayi Sugar transporter family protein 0.0099 0.209 0.6548
Plasmodium falciparum lysine--tRNA ligase 0.0022 0.0196 0.0092
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0384 0.0658
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0126 0.2769 0.4292
Loa Loa (eye worm) hypothetical protein 0.0058 0.1093 0.3198
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0917 0.1918
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0408 0.3318
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.1093 0.3423
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0222
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0917 0.1918
Mycobacterium tuberculosis Probable oxidoreductase 0.014 0.3117 0.4855
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0126 0.0222
Loa Loa (eye worm) hypothetical protein 0.0022 0.0196 0.0295
Giardia lamblia Lysyl-tRNA synthetase 0.0022 0.0196 0.2742
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0399 0.0693
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0408 0.3597
Leishmania major glucose transporter, lmgt2 0.0031 0.0408 0.3318
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0022 0.0196 0.1373
Schistosoma mansoni hypothetical protein 0.019 0.4337 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0408 0.3318
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0126 0.0631
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0917 0.1918
Entamoeba histolytica protein kinase, putative 0.003 0.0399 1
Leishmania major glucose transporter, lmgt1 0.0031 0.0408 0.3318
Brugia malayi Cam kinase protein 1 0.003 0.0399 0.1249
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0693 0.1388
Toxoplasma gondii facilitative glucose transporter GT1 0.0099 0.209 0.3084
Loa Loa (eye worm) hypothetical protein 0.0024 0.0246 0.0457
Echinococcus multilocularis GPCR, family 2 0.0018 0.0108 0.0006
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0505 0.4375
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0099 0.209 0.4691
Echinococcus granulosus calcium dependent protein kinase 0.0028 0.0353 0.0584
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0693 0.2885
Mycobacterium leprae Probable lipase LipE 0.0042 0.0693 0.1926
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0693 0.1926
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0693 0.0935
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0399 0.139
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0693 0.2885
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0693 0.0935
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.1018 0.2158
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0693 0.643
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0196 0.1248
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.003 0.0399 0.1249
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.003 0.0399 0.095
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.1352 0.2945
Brugia malayi jmjC domain containing protein 0.0069 0.1352 0.4234
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0108 0.0338
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.003 0.0399 0.0297
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.1093 0.3198
Schistosoma mansoni protein kinase 0.003 0.0399 0.0693
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Plasmodium vivax calcium-dependent protein kinase, putative 0.003 0.0399 0.0297
Leishmania major hypothetical protein, conserved 0.0042 0.0693 0.643
Plasmodium vivax lysine--tRNA ligase, putative 0.0022 0.0196 0.0092
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0505 0.0404
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0108 0.0008
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.003 0.0399 0.0457
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0693 0.1388
Echinococcus multilocularis geminin 0.019 0.4337 1
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.1018 1
Loa Loa (eye worm) sugar transporter 0.0099 0.209 0.643
Plasmodium falciparum mitogen-activated protein kinase 2 0.016 0.3592 0.3524
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0126 0.2769 0.4292
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0408 0.1439
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0408 0.1439
Plasmodium falciparum calcium-dependent protein kinase 5 0.003 0.0399 0.0297
Brugia malayi beta-lactamase family protein 0.0042 0.0693 0.217
Leishmania major glucose transporter, lmgt3 0.0031 0.0408 0.3318
Loa Loa (eye worm) hypothetical protein 0.004 0.0637 0.1722
Toxoplasma gondii lysine-tRNA ligase 0.0022 0.0196 0.0141
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0126 0.2769 0.4292
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.003 0.0399 0.3213
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Toxoplasma gondii thioredoxin reductase 0.0055 0.1018 0.1419
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0006
Loa Loa (eye worm) hypothetical protein 0.003 0.0384 0.0902
Plasmodium falciparum calcium-dependent protein kinase 4 0.003 0.0399 0.0297
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0408 0.3318
Treponema pallidum NADH oxidase 0.0019 0.0126 0.5
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0917 0.1918
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0269 0.6299 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0408 0.3318
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.014 0.3117 0.4855
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0917 0.2872
Leishmania major lysyl-tRNA synthetase, putative 0.0022 0.0196 0.0997
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0006
Brugia malayi jmjC domain containing protein 0.0018 0.0105 0.033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0399 0.0693
Brugia malayi glutathione reductase 0.0055 0.1018 0.3191
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0126 0.0222
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0505 0.4375
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.1352 0.4037
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0693 0.2885
Plasmodium falciparum hexose transporter 0.0099 0.209 0.2006
Leishmania major protein kinase, putative 0.003 0.0399 0.3213
Schistosoma mansoni hypothetical protein 0.019 0.4337 1
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0408 0.1439
Schistosoma mansoni protein kinase 0.003 0.0399 0.0693
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0408 0.3597
Schistosoma mansoni glucose transport protein 0.0099 0.209 0.4691
Loa Loa (eye worm) hypothetical protein 0.0018 0.0108 0.0008
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0126 0.0394
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0693 0.0593
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0693 0.658
Loa Loa (eye worm) hypothetical protein 0.0042 0.0693 0.1902
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0505 0.0404
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.209 0.4691
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.1093 0.3423

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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