TDR Targets

Basic information

Technical information

TDR Targets ID: 1325063
Name: N-[1-(4-propyl-5-sulfanylidene-1H-1,2,4-triaz ol-3-yl)ethyl]benzenesulfonamide
MW: 326.438 | Formula: C13H18N4O2S2
H donors: 1 H acceptors: 4 LogP: 1.63 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCCn1c(nnc1S)C(NS(=O)(=O)c1ccccc1)C
InChi: 1S/C13H18N4O2S2/c1-3-9-17-12(14-15-13(17)20)10(2)16-21(18,19)11-7-5-4-6-8-11/h4-8,10,16H,3,9H2,1-2H3,(H,15,20)
InChiKey: COLHOTOPWFWVAV-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[1-(4-propyl-5-thioxo-1H-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Mus musculus	RAR-related orphan receptor gamma	Starlite/ChEMBL	No references
Giardia intestinalis	Putative fructose-1,6-bisphosphate aldolase	Starlite/ChEMBL	No references
Homo sapiens	lysine (K)-specific demethylase 4A	Starlite/ChEMBL	No references
Homo sapiens	euchromatic histone-lysine N-methyltransferase 2	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	Probable JmjC domain-containing histone demethylation protein 3B, putative	Get druggable targets OG5_127917	All targets in OG5_127917
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	Get druggable targets OG5_131470	All targets in OG5_131470
Giardia lamblia	Fructose-bisphosphate aldolase	Get druggable targets OG5_129214	All targets in OG5_129214
Treponema pallidum	fructose-bisphosphate aldolase	Get druggable targets OG5_129214	All targets in OG5_129214
Echinococcus granulosus	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127917	All targets in OG5_127917
Brugia malayi	Pre-SET motif family protein	Get druggable targets OG5_131470	All targets in OG5_131470
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma mansoni	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Echinococcus multilocularis	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Trichomonas vaginalis	set domain proteins, putative	Get druggable targets OG5_131470	All targets in OG5_131470
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Schistosoma japonicum	JmjC domain-containing histone demethylation protein 3C, putative	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Echinococcus granulosus	Transcription factor JmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Loa Loa (eye worm)	jmjC domain-containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Onchocerca volvulus		Get druggable targets OG5_131470	All targets in OG5_131470
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	Get druggable targets OG5_129214	All targets in OG5_129214

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	Putative fructose-1,6-bisphosphate aldolase	323 aa	361 aa	25.8 %
Candida albicans	fructose-bisphosphate aldolase	Putative fructose-1,6-bisphosphate aldolase	323 aa	358 aa	22.6 %
Candida albicans	fructose-bisphosphate aldolase	Putative fructose-1,6-bisphosphate aldolase	323 aa	358 aa	22.6 %
Mycobacterium ulcerans	fructose-bisphosphate aldolase	Putative fructose-1,6-bisphosphate aldolase	323 aa	361 aa	26.9 %
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	Putative fructose-1,6-bisphosphate aldolase	323 aa	361 aa	25.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0286	0.7898	1
Loa Loa (eye worm)	hypothetical protein	0.0194	0.5	0.734
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0036	0.0042	0.0053
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0194	0.5	0.4639
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Onchocerca volvulus		0.0194	0.5	0.6324
Echinococcus multilocularis	aldo keto reductase	0.0194	0.5	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Plasmodium falciparum	aldo-keto reductase, putative	0.0056	0.0673	1
Mycobacterium leprae	PROBABLE OXIDOREDUCTASE	0.0194	0.5	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0194	0.5	0.4639
Leishmania major	aldehyde reductase, putative,oxidoreductase, putative	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase	0.0194	0.5	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Leishmania major	aldo-keto reductase-like protein	0.0194	0.5	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Echinococcus multilocularis	jumonji domain containing protein	0.0049	0.0448	0.0869
Brugia malayi	Pre-SET motif family protein	0.0036	0.0042	0.0039
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Giardia lamblia	Aldose reductase	0.0194	0.5	0.4992
Giardia lamblia	Fructose-bisphosphate aldolase	0.0353	1	1
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0172	0.4327	0.8444
Loa Loa (eye worm)	oxidoreductase	0.0194	0.5	0.734
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Echinococcus granulosus	jumonji domain containing protein	0.0049	0.0448	0.0897
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Echinococcus granulosus	aldo keto reductase family 1, member B4	0.0056	0.0673	0.1346
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Brugia malayi	Pre-SET motif family protein	0.0251	0.6807	1
Echinococcus granulosus	aldo keto reductase	0.0194	0.5	1
Echinococcus granulosus	peregrin	0.0035	0.0015	0.003
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Plasmodium vivax	aldehyde reductase, putative	0.0056	0.0673	1
Brugia malayi	glutamate-cysteine ligase modifier subunit	0.0056	0.0673	0.0969
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Leishmania major	prostaglandin f synthase, putative	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Toxoplasma gondii	aldose reductase, putative	0.0194	0.5	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Brugia malayi	Cytochrome P450 family protein	0.0045	0.0338	0.0476
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Onchocerca volvulus		0.0194	0.5	0.6324
Toxoplasma gondii	aldo/keto reductase family oxidoreductase	0.0056	0.0673	0.132
Trypanosoma brucei	aldo-keto reductase, putative	0.0194	0.5	1
Trichomonas vaginalis	aldo/keto reductase, putative	0.0194	0.5	0.4639
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0194	0.5	0.734
Echinococcus multilocularis	aldehyde reductase	0.0138	0.3236	0.6461
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0194	0.5	0.734
Trypanosoma cruzi	aldo-keto reductase	0.0194	0.5	1
Schistosoma mansoni	pol-related	0.0194	0.5	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Trichomonas vaginalis	set domain proteins, putative	0.0286	0.7898	0.7746
Schistosoma mansoni	potassium channel beta	0.0056	0.0673	0.132
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0115	0.2532	0.505
Loa Loa (eye worm)	oxidoreductase	0.0194	0.5	0.734
Schistosoma mansoni	aldo-keto reductase	0.0194	0.5	1
Loa Loa (eye worm)	cytochrome P450 family protein	0.0045	0.0338	0.0476
Echinococcus granulosus	aldehyde reductase	0.0138	0.3236	0.6471
Brugia malayi	NADH-dependent xylose reductase	0.0056	0.0673	0.0969
Onchocerca volvulus		0.0056	0.0673	0.0835
Brugia malayi	jmjC domain containing protein	0.0043	0.0248	0.0343
Mycobacterium leprae	Conserved hypothetical protein	0.0138	0.3236	0.5922
Onchocerca volvulus		0.0194	0.5	0.6324
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0036	0.0042	0.0053
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0251	0.6807	1
Loa Loa (eye worm)	oxidoreductase	0.0194	0.5	0.734
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Loa Loa (eye worm)	hypothetical protein	0.006	0.0806	0.1164
Entamoeba histolytica	aldose reductase, putative	0.0194	0.5	0.4639
Plasmodium falciparum	aldehyde reductase, putative	0.0056	0.0673	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Mycobacterium ulcerans	oxidoreductase	0.0194	0.5	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Plasmodium vivax	SET domain protein, putative	0.0036	0.0042	0.0402
Leishmania major	prostaglandin f2-alpha synthase/D-arabinose dehydrogenase	0.0194	0.5	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0042	0.0053
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Echinococcus granulosus	hypothetical protein	0.0194	0.5	1
Trypanosoma cruzi	aldo/keto reductase, putative	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Echinococcus multilocularis	voltage gated potassium channel subunit	0.0056	0.0673	0.132
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0194	0.5	0.734
Echinococcus granulosus	histone lysine methyltransferase setb	0.0036	0.0042	0.0083
Trypanosoma brucei	prostaglandin f synthase	0.0194	0.5	1
Schistosoma mansoni	jumonji domain containing protein	0.0092	0.1788	0.3556
Trichomonas vaginalis	aldo/keto reductase, putative	0.0194	0.5	0.4639
Echinococcus granulosus	PHD finger protein rhinoceros	0.0035	0.0015	0.003
Echinococcus multilocularis	aldo keto reductase	0.0194	0.5	1
Entamoeba histolytica	aldose reductase, putative	0.0194	0.5	0.4639
Loa Loa (eye worm)	glutamate-cysteine ligase modifier subunit	0.0056	0.0673	0.0969
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0036	0.0042	0.0053
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0194	0.5	0.734
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0036	0.0042	0.0053
Giardia lamblia	Aldose reductase	0.0194	0.5	0.4992
Mycobacterium tuberculosis	Probable oxidoreductase	0.0194	0.5	1
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0172	0.4327	0.8444
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0353	1	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0194	0.5	0.4639
Echinococcus granulosus	aldo keto reductase	0.0194	0.5	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0042	0.0053
Plasmodium vivax	oxidoreductase, aldo/keto reductase domain containing protein	0.0056	0.0673	1
Loa Loa (eye worm)	oxidoreductase	0.0194	0.5	0.734
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0042	0.0053
Toxoplasma gondii	oxidoreductase, aldo/keto reductase family protein	0.0056	0.0673	0.132
Entamoeba histolytica	aldose reductase, putative	0.0194	0.5	0.4639
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0043	0.0248	0.0467
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Brugia malayi	jmjC domain containing protein	0.0115	0.2532	0.3706
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Onchocerca volvulus		0.0194	0.5	0.6324
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Onchocerca volvulus		0.0194	0.5	0.6324
Treponema pallidum	fructose-bisphosphate aldolase	0.0353	1	0.5
Toxoplasma gondii	aldo-keto reductase	0.0056	0.0673	0.132
Loa Loa (eye worm)	jmjC domain-containing protein	0.0043	0.0248	0.0343
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0043	0.0248	0.0467
Echinococcus multilocularis	lysine specific demethylase 5A	0.0043	0.0248	0.0467
Schistosoma mansoni	aldo-keto reductase	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase	0.0194	0.5	1
Onchocerca volvulus		0.0036	0.0042	0.0034
Trichomonas vaginalis	aldo/keto reductase, putative	0.0194	0.5	0.4639
Echinococcus granulosus	aldo keto reductase	0.0194	0.5	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0194	0.5	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0353	1	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0194	0.5	1
Echinococcus granulosus	voltage gated potassium channel subunit	0.0056	0.0673	0.1346
Loa Loa (eye worm)	jmjC domain-containing protein	0.0073	0.1193	0.1735
Onchocerca volvulus		0.0194	0.5	0.6324
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0042	0.0039
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0115	0.2532	0.5065
Loa Loa (eye worm)	oxidoreductase	0.0194	0.5	0.734
Echinococcus granulosus	lysine specific demethylase 5A	0.0043	0.0248	0.0496
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.0172	0.4327	0.8444
Trichomonas vaginalis	aldo-keto reductase, putative	0.0194	0.5	0.4639

Activities

Activity type	Activity value	Assay description	Source	Reference
EC50 (functional)	> 53 uM	PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory)	ChEMBL.	No reference
IC50 (functional)	> 47.1 uM	PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	3.1623 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402]	ChEMBL.	No reference
Potency (functional)	= 10 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ]	ChEMBL.	No reference
Potency (functional)	= 10 um	PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	19.9526 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404]	ChEMBL.	No reference
Potency (functional)	44.6684 uM	PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	56.2341 uM	PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771]	ChEMBL.	No reference
Potency (functional)	89.1251 uM	PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1470438

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1325063