TDR Targets

Basic information

Technical information

TDR Targets ID: 1361047
Name: 1-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]- 2-(2-methoxyphenoxy)ethanone
MW: 424.898 | Formula: C19H21ClN2O5S
H donors: 0 H acceptors: 3 LogP: 2.64 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccccc1OCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)Cl
InChi: 1S/C19H21ClN2O5S/c1-26-17-4-2-3-5-18(17)27-14-19(23)21-10-12-22(13-11-21)28(24,25)16-8-6-15(20)7-9-16/h2-9H,10-14H2,1H3
InChiKey: ACROIKWQTOUGLQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

1-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]-2-(2-methoxyphenoxy)ethanone
T5392851
ZINC03609782

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	SMAD family member 2	Starlite/ChEMBL	No references
Homo sapiens	parathyroid hormone 1 receptor	Starlite/ChEMBL	No references
Homo sapiens	GNAS complex locus	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Brugia malayi	MH2 domain containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	transcription factor SMAD2	Get druggable targets OG5_131716	All targets in OG5_131716
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma japonicum	ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	MH2 domain-containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma japonicum	ko:K04588 secretin receptor, putative	Get druggable targets OG5_139196	All targets in OG5_139196

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Schistosoma mansoni	GTP-binding protein alpha subunit gna	GNAS complex locus	394 aa	450 aa	28.7 %
Brugia malayi	MH2 domain containing protein	SMAD family member 2	467 aa	405 aa	31.6 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.0269	0.3066
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0019	0.0116	0.0116
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0298	0.0298
Trypanosoma brucei	Emopamil binding protein, putative	0.0133	0.3458	0.3458
Brugia malayi	Latrophilin receptor protein 2	0.0019	0.0116	0.0116
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1178	0.2951
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.027	0.3078
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0019	0.0116	0.0983
Brugia malayi	hypothetical protein	0.0016	0.0035	0.0035
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0608	0.6922
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.006	0.1324	0.1324
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.0097
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Loa Loa (eye worm)	thioredoxin reductase	0.0047	0.0948	0.0948
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.027	0.3078
Trypanosoma cruzi	Emopamil binding protein, putative	0.0133	0.3458	0.3458
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0019	0.0116	0.0116
Toxoplasma gondii	thioredoxin reductase	0.0047	0.0948	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0347	0.3945
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.0269	0.3066
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1178	0.2951
Schistosoma mansoni	hypothetical protein	0.0019	0.0116	0.029
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0347	0.3945
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0108	0.273	0.8837
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0339	0.3855
Trypanosoma cruzi	3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative	0.0133	0.3458	0.3458
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0415	0.4722
Onchocerca volvulus		0.0133	0.3458	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0608	0.6922
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0045	0.0879	0.0879
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.027	0.3078
Schistosoma mansoni	hypothetical protein	0.0041	0.0765	0.1915
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0045	0.0879	0.0879
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0016	0.0039	0.0039
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0033	0.054	0.5514
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.1178	1
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Schistosoma mansoni	hypothetical protein	0.0019	0.0116	0.029
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase, LpdB	0.0016	0.0039	0.5
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0045	0.0879	0.2201
Leishmania major	2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein	0.0016	0.0039	0.0039
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0298	0.0298
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0036	0.0609	0.0609
Treponema pallidum	NADH oxidase	0.0016	0.0039	0.5
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0045	0.0879	0.0879
Brugia malayi	latrophilin 2 splice variant baaae	0.0041	0.0765	0.0765
Trypanosoma cruzi	3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative	0.0133	0.3458	0.3458
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0016	0.0039	0.0039
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0047	0.0948	0.8043
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.027	0.3078
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.006	0.1324	0.1324
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0298	0.2855
Brugia malayi	MH2 domain containing protein	0.0144	0.3789	0.3789
Brugia malayi	hypothetical protein	0.0025	0.0298	0.0298
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.0298	0.2855
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.012	0.3084	1
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Plasmodium falciparum	thioredoxin reductase	0.0047	0.0948	1
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0298	0.2855
Mycobacterium ulcerans	flavoprotein disulfide reductase	0.0016	0.0039	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0608	0.6922
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.1178	1
Trichomonas vaginalis	mercuric reductase, putative	0.0016	0.0039	0.044
Leishmania major	trypanothione reductase	0.0047	0.0948	0.0948
Plasmodium falciparum	glutathione reductase	0.0047	0.0948	1
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0045	0.0879	0.0879
Brugia malayi	glutathione reductase	0.0047	0.0948	0.0948
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0765	0.0765
Leishmania major	acetoin dehydrogenase e3 component-like protein	0.0016	0.0039	0.0039
Trichomonas vaginalis	glutathione reductase, putative	0.0016	0.0039	0.044
Trichomonas vaginalis	PIKK family atypical protein kinase	0.003	0.0443	0.5047
Leishmania major	hypothetical protein, conserved	0.0025	0.0298	0.0298
Trypanosoma cruzi	target of rapamycin kinase 3	0.0036	0.0609	0.0609
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0045	0.0879	0.7457
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.012	0.3084	1
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0016	0.0039	0.5
Loa Loa (eye worm)	glutathione reductase	0.0047	0.0948	0.0948
Trypanosoma brucei	trypanothione reductase	0.0047	0.0948	0.0948
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0108	0.273	0.8837
Loa Loa (eye worm)	phosphatidylinositol 3	0.0045	0.0879	0.0879
Trypanosoma brucei	C-8 sterol isomerase, putative	0.0356	1	1
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0016	0.0039	0.5
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0045	0.0879	0.0879
Brugia malayi	Thioredoxin reductase	0.0047	0.0948	0.0948
Mycobacterium tuberculosis	Probable reductase	0.0108	0.273	0.8837
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.0328
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0108	0.273	0.8837
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0879	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.1178	1
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.3789	0.3789
Schistosoma mansoni	hypothetical protein	0.0019	0.0116	0.029
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.0039
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0045	0.0879	0.0879
Echinococcus granulosus	GPCR family 2	0.0019	0.0116	0.0983
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0879	1
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0045	0.0879	0.7457
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.0045	0.0879	0.5
Trypanosoma cruzi	trypanothione reductase, putative	0.0016	0.0039	0.0039
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0019	0.0116	0.0983
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0036	0.0609	0.0609
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0045	0.0879	0.0879
Echinococcus multilocularis	GPCR, family 2	0.0019	0.0116	0.0983
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0116	0.0116
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0298	0.0298
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.1178	0.2951
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.0021	0.0182	0.0182
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0608	0.6922
Loa Loa (eye worm)	hypothetical protein	0.006	0.1324	0.1324
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.0269	0.3066
Plasmodium vivax	glutathione reductase, putative	0.0047	0.0948	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0038	0.0685	0.78
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0339	0.3855
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Echinococcus granulosus	thioredoxin glutathione reductase	0.0047	0.0948	0.8043
Loa Loa (eye worm)	hypothetical protein	0.0182	0.4894	0.4894
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.1178	0.1178
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.0045	0.0879	0.5
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0298	0.2855
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.1178	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0879	1
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0016	0.0039	0.0039
Plasmodium vivax	thioredoxin reductase, putative	0.0047	0.0948	1
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.1178	0.1178
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0108	0.273	0.8837
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Loa Loa (eye worm)	hypothetical protein	0.0356	1	1
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.0356	1	1
Giardia lamblia	GTOR	0.0045	0.0879	1
Leishmania major	C-8 sterol isomerase-like protein	0.0356	1	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.3789	0.3789
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0016	0.0039	0.5
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0019	0.0116	0.0983
Leishmania major	hypothetical protein, conserved	0.0133	0.3458	0.3458
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0298	0.0298
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0019	0.0116	0.0983
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0016	0.0039	0.0039
Leishmania major	3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative	0.0133	0.3458	0.3458
Mycobacterium tuberculosis	Probable dehydrogenase	0.0108	0.273	0.8837
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.0328
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0016	0.0039	0.0039
Trypanosoma cruzi	trypanothione reductase, putative	0.0047	0.0948	0.0948
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0347	0.3945
Schistosoma mansoni	hypothetical protein	0.0019	0.0116	0.029
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.0019	0.0106	0.0106
Mycobacterium tuberculosis	Probable oxidoreductase	0.012	0.3084	1
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0016	0.0039	0.0039
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.054	0.6145
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.0039
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0608	0.6922
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0047	0.0948	0.2985
Trypanosoma cruzi	Emopamil binding protein, putative	0.0133	0.3458	0.3458
Brugia malayi	Calcitonin receptor-like protein seb-1	0.006	0.1324	0.1324
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase	0.0016	0.0039	0.5
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.012	0.3084	1

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	0.631 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860]	ChEMBL.	No reference
Potency (functional)	7.0795 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	8.2753 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	10.4179 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	12.5893 uM	PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	44.6684 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Plasmodium falciparum	ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1476145

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1361047